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General Material Information

Preferred name acorus calamus rhizome oil
Trivial Name Oils, Acorus calamus
Short Description essential oil obtained from the rhizomes of the calamus, acorus calamus l., araceae
CAS Number 8015-79-0
FDA UNII 5F9K5X640P
COE Number 13
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8015-79-0 ; CALAMUS OIL--PROHIBITED
Synonyms
  • acorus americanus rhizome oil
  • acorus angustatus rhizome oil
  • acorus angustifolius rhizome oil
  • acorus asiaticus rhizome oil
  • acorus calamus var. americanus rhizome oil
  • acorus calamus var. angustatus rhizome oil
  • acorus calamus var. angustifolius rhizome oil
  • acorus calamus var. spurius rhizome oil
  • acorus calamus var. verus rhizome oil
  • acorus calamus var. vulgaris rhizome oil
  • acorus cochinchinensis rhizome oil
  • acorus griffithii rhizome oil
  • acorus spurius rhizome oil
  • acorus triqueter rhizome oil
  • acorus verus rhizome oil
  • calamus EO
  • calamus oil
  • calamus oil korea, (azarone
  • calamus oil korea, (azarone
  • calamus rhizome oil
  • calamus rhizome oil (acorus calamus)
  • calamus root essential oil
  • sweet cane rhizome oil (acorus calamus)
  • cane sweet rhizome oil (acorus calamus)
  • sweet cinnamon rhizome oil (acorus calamus)
  • cinnamon sweet rhizome oil (acorus calamus)
  • essential oil obtained from the rhizomes of the calamus, acorus calamus l., araceae
  • sweet flag rhizome oil (acorus calamus)
  • flag sweet rhizome oil (acorus calamus)
  • sweet myrtle rhizome oil (acorus calamus)
  • myrtle sweet rhizome oil (acorus calamus)
  • orontium cochinchinense rhizome oil
  • acorus calamus l. rhizome oil
  • Oils, Acorus calamus
  • Oil of sweet flag
  • Sweet flag Oil
  • Oil of Calamus
  • Oils, calamus

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Literature & References

acorus calamus l. rhizome oil
Canada Domestic Sub. List:8015-79-0
Pubchem (sid):135326359
Publications by PubMed
A comparison on the phytoremediation ability of triazophos by different macrophytes.
Spatio-temporal patterns in rhizosphere oxygen profiles in the emergent plant species Acorus calamus.
Roles of root porosity, radial oxygen loss, Fe plaque formation on nutrient removal and tolerance of wetland plants to domestic wastewater.
Effects of perchlorate on growth of four wetland plants and its accumulation in plant tissues.
Consumer and farmer safety evaluation of application of botanical pesticides in black pepper crop protection.
Terpenoid composition and antifungal activity of three commercially important essential oils against Aspergillus flavus and Aspergillus niger.
Diurnal fluctuations in oxygen release from roots of Acorus calamus Linn in a modeled constructed wetland.
Antimycobacterial screening of traditional medicinal plants using the microplate resazurin assay.
Asarone inhibits adipogenesis and stimulates lipolysis in 3T3-L1 adipocytes.
Antimutagenic activity of methanolic extracts of four ayurvedic medicinal plants.
Atrazine degradation by aerobic microorganisms isolated from the rhizosphere of sweet flag (Acorus calamus L.).
Evaluation of anti-methicillin-resistant Staphylococcus aureus (MRSA) activity and synergy of some bioactive plant extracts.
Developmental anatomy of the root cortex of the basal monocotyledon, Acorus calamus (Acorales, Acoraceae).
Study of antidiarrhoeal activity of four medicinal plants in castor-oil induced diarrhoea.
Getting to the root (Acorus calamus) of the problem.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Acid Value 4 max KOH/g
Solubility
alcohol Yes
water No
Stability
lipstick Unspecified
non-discoloring in most media Unspecified
powder Unspecified

Organoleptic Properties

Odor Type: Herbal
fresh, sweet, herbal, citrus, spicy, woody
Odor strength medium
Substantivity 108 hour(s) at 100.00 %
Luebke, William tgsc, (1986) At 100.00 %. fresh sweet herbal citrus spicy woody

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 777 mg/kg
BEHAVIORAL: TREMOR
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

intraperitoneal-rat LD50 221 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.

intravenous-mouse LD50 1138 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Dissertationes Pharmaceuticae. Vol. 16, Pg. 447, 1964.

intraperitoneal-mouse LD50 177 mg/kg
Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 163, 1959.

intraperitoneal-guinea pig LD50 297 mg/kg
BEHAVIORAL: TETANY BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Antibiotics and Chemotherapy Vol. 7, Pg. 378, 1957.

Dermal Toxicity:
skin-guinea pig LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
cis- and trans-Asarone as such should not be used as fragrance ingredients; essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in consumer products.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
methyl eugenol Max. Found:
eugenol Max. Found: 0.2 % and Reason: Sensitization
farnesol Max. Found: 0.5 % and Reason: Sensitization
trans-asarone Max. Found: 0.7 % and Reason: Carcinogenicity
cis-asarone Max. Found: 70.00 % and Reason: Carcinogenicity
Recommendation for acorus calamus rhizome oil usage levels up to:
4.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -3.80000
beverages(nonalcoholic): -2.00000
beverages(alcoholic): 5.0000015.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.50000
fruit ices: -1.50000
gelatins / puddings: -0.02000
granulated sugar: --
gravies: --
hard candy: -3.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8015-79-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
acorus calamus l. rhizome oil
Chemidplus:0008015790