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General Material Information

Preferred name eucalyptus globulus oil
Trivial Name Eucalyptus oil
Short Description oil obtained from the fresh leaves of the eucaluptus, eucalyptus globulus and other species of eucalyptus, myrtaceae. syn. yuukari yu (japanese)
CAS Number 8000-48-4
FEMA Number 2466
FDA UNII 2R04ONI662
MDL MFCD00146880
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8000-48-4 ; EUCALYPTUS, OIL (EUCALYPTUS GLOBULUS LABILLE)
Synonyms
  • dinkum oil
  • eucalyptus 80/85%
  • eucalyptus ess. oil (for fragrance) (Robertet)
  • eucalyptus forte
  • eucalyptus forte spain (Robertet)
  • eucalyptus globulus 70% oil
  • eucalyptus globulus 70/74 essential oil
  • eucalyptus globulus 80% oil
  • eucalyptus globulus 80/84 essential oil
  • eucalyptus globulus EO
  • eucalyptus globulus EO 80%
  • eucalyptus globulus essential oil
  • eucalyptus globulus labille oil
  • eucalyptus globulus leaf oil
  • eucalyptus globulus oil organic
  • eucalyptus globulus oil spain
  • eucalyptus globulus oil spain / portugal organic
  • eucalyptus oil (80/85)
  • eucalyptus oil (eucalyptus globulus labille)
  • eucalyptus oil 70/75
  • eucalyptus oil 80/85
  • eucalyptus oil 80/85 (ex globulus)
  • eucalyptus oil 80/85% FCC
  • eucalyptus oil china
  • eucalyptus oil natural (60%,70%,globulus 80%,99.5%)
  • eucalyptus oil redistilled pharmaceutical grade
  • eucalyptus oil, tech. grade
  • hydroessential eucalyptus (Vevy)
  • oil eucalyptus globulus 80/85% FCC
  • oil obtained from the fresh leaves of the eucaluptus, eucalyptus globulus and other species of eucalyptus, myrtaceae. syn. yuukari yu (japanese)
  • Eucalyptus oil
  • Oils, eucalyptus
  • Oils, essential, eucalyptus
  • Essential oils, eucalyptus
  • Eucalyptus leaf oil
  • Eucalyptus essential oil
  • Essential eucalyptus oil
  • Eucalyptus terpene oil
  • Oil of Eucalyptus
  • Eucalyptus Liq. E
  • Oleum eucalyptus
  • Eucalyptus Liquid E
  • Oleum eucalypti

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Literature & References

eucalyptus globulus leaf oil
Canada Domestic Sub. List:8000-48-4
Pubchem (sid):135264270
Publications by PubMed
Hormonal dynamics during recovery from drought in two Eucalyptus globulus genotypes: From root to leaf.
Molluscicidal and antischistosomal activities of methanol extracts and isolated compounds from Eucalyptus globulus and Melaleuca styphelioides.
Co-ordination of growth, gas exchange and hydraulics define the carbon safety margin in tree species with contrasting drought strategies.
Localization of polysaccharides in isolated and intact cuticles of eucalypt, poplar and pear leaves by enzyme-gold labelling.
Root damage by insects reverses the effects of elevated atmospheric CO2 on Eucalypt seedlings.
Carbon dynamics of eucalypt seedlings exposed to progressive drought in elevated [CO2] and elevated temperature.
Application of phytogenic zerovalent iron nanoparticles in the adsorption of hexavalent chromium.
Effects of essential oils from Eucalyptus globulus leaves on soil organisms involved in leaf degradation.
Whole-plant versus leaf-level regulation of photosynthetic responses after partial defoliation in Eucalyptus globulus saplings.
A latitudinal cline in disease resistance of a host tree.
Qualitative and semi-quantitative analysis of phenolics in Eucalyptus globulus leaves by high-performance liquid chromatography coupled with diode array detection and electrospray ionisation mass spectrometry.
Interactive effects of water supply and defoliation on photosynthesis, plant water status and growth of Eucalyptus globulus Labill.
Ecophysiological responses of a young blue gum (Eucalyptus globulus) plantation to weed control.
Site-specific responses to short-term environmental variation are reflected in leaf and phloem-sap carbon isotopic abundance of field grown Eucalyptus globulus.
A controlled test of the dual-isotope approach for the interpretation of stable carbon and oxygen isotope ratio variation in tree rings.
Consequences of resource limitation for recovery from repeated defoliation in Eucalyptus globulus Labilladière.
Chemical composition and antimicrobial effects of essential oils of Eucalyptus globulus, Myrtus communis and Satureja hortensis against Escherichia coli O157:H7 and Staphylococcus aureus in minced beef.
Screening of allelopathic trees for their antifungal potential against Alternaria alternata strains isolated from dying-back Eucalyptus spp.
Are gas exchange responses to resource limitation and defoliation linked to source:sink relationships?
Compound-specific differences in (13)C of soluble carbohydrates in leaves and phloem of 6-month-old Eucalyptus globulus (Labill).
Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens.
miRNA control of vegetative phase change in trees.
Seasonal patterns of foliage respiration in dominant and suppressed Eucalyptus globulus canopies.
Observed and modelled leaf area index in Eucalyptus globulus plantations: tests of optimality and equilibrium hypotheses.
Eucalyptus leaf extract suppresses the postprandial elevation of portal, cardiac and peripheral fructose concentrations after sucrose ingestion in rats.
Differences in Rubisco content and its synthesis in leaves at different positions in Eucalyptus globulus seedlings.
Phloem sap and leaf delta13C, carbohydrates, and amino acid concentrations in Eucalyptus globulus change systematically according to flooding and water deficit treatment.
A geographic mosaic of genetic variation within a foundation tree species and its community-level consequences.
Plasticity in maximum stomatal conductance constrained by negative correlation between stomatal size and density: an analysis using Eucalyptus globulus.
Comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics.
Marker constituents of the natural antioxidant Eucalyptus leaf extract for the evaluation of food additives.
Role of corticular photosynthesis following defoliation in Eucalyptus globulus.
A comparison of growth, photosynthetic capacity and water stress in Eucalyptus globulus coppice regrowth and seedlings during early development.
Shifts in biomass and resource allocation patterns following defoliation in Eucalyptus globulus growing with varying water and nutrient supplies.
Oxygen and nitrogen reactive species are effectively scavenged by Eucalyptus globulus leaf water extract.
Acclimation to short-term low temperatures in two Eucalyptus globulus clones with contrasting drought resistance.
Development of Nested Polymerase Chain Reaction Detection of Mycosphaerella spp. and Its Application to the Study of Leaf Disease in Eucalyptus Plantations.
Characterization of juvenile and adult leaves of Eucalyptus globulus showing distinct heteroblastic development: photosynthesis and volatile isoprenoids.
Few Mendelian genes underlie the quantitative response of a forest tree, Eucalyptus globulus, to a natural fungal epidemic.
Retranslocation of foliar nutrients in evergreen tree species planted in a Mediterranean environment.
Novel mannose-sequestration technique reveals variation in subcellular orthophosphate pools do not explain the effects of phosphorus nutrition on photosynthesis in Eucalyptus globulus seedlings.
Stability of genetic-based defensive chemistry across life stages in a Eucalyptus species.
Within-canopy nitrogen and photosynthetic gradients are unaffected by soil fertility in field-grown Eucalyptus globulus.
Increased photosynthesis following partial defoliation of field-grown Eucalyptus globulus seedlings is not caused by increased leaf nitrogen.
Modelling advection and diffusion of water isotopologues in leaves.
Defoliation and nitrogen effects on photosynthesis and growth of Eucalyptus globulus.
Internal conductance does not scale with photosynthetic capacity: implications for carbon isotope discrimination and the economics of water and nitrogen use in photosynthesis.
Physiology and anatomy of lenticel-like structures on leaves of Eucalyptus nitens and Eucalyptus globulus seedlings.
Photosynthesis of Eucalyptus globulus with Mycosphaerella leaf disease.
Antibacterial effects of Eucalyptus globulus leaf extract on pathogenic bacteria isolated from specimens of patients with respiratory tract disorders.
Precision and accuracy of pest and pathogen damage assessment in young eucalypt plantations.
Degradation of leaf litter phenolics by aquatic and terrestrial isopods.
PCR-identification of Mycosphaerella species associated with leaf diseases of Eucalyptus.
Eucalyptus leaf extract inhibits intestinal fructose absorption, and suppresses adiposity due to dietary sucrose in rats.
A specific primer PCR and RFLP assay for the rapid detection and differentiation in planta of some Mycosphaerella species associated with foliar diseases of Eucalyptus globulus.
Growth efficiency increases as relative growth rate increases in shoots and roots of Eucalyptus globulus deprived of nitrogen or treated with salt.
Capillary electrophoresis of the major anions and cations in leaf extracts of woody species.
Environmental and physiological controls over oxygen and carbon isotope composition of Tasmanian blue gum, Eucalyptus globulus.
Responses to water stress in two Eucalyptus globulus clones differing in drought tolerance.
Antimicrobial activities of eucalyptus leaf extracts and flavonoids from Eucalyptus maculata.
Ovicidal and adulticidal activity of Eucalyptus globulus leaf oil terpenoids against Pediculus humanus capitis (Anoplura: Pediculidae).
Effects of Eucalyptus plantations on detritus, decomposers, and detritivores in streams.
Leaf orientation, light interception and stomatal conductance of Eucalyptus globulus ssp. globulus leaves.
Water deficits are more important in delaying growth than in changing patterns of carbon allocation in Eucalyptus globulus.
Movement and regeneration of epicuticular waxes through plant cuticles.
Effects of thinning on wood production, leaf area index, transpiration and canopy interception of a plantation subject to drought.
Growth, leaf morphology, water use and tissue water relations of Eucalyptus globulus clones in response to water deficit.
Influence of light availability on leaf structure and growth of two Eucalyptus globulus ssp. globulus provenances.
Foliar nutrient retranslocation in Eucalyptus globulus.
Emission of isoprene from salt-stressed Eucalyptus globulus leaves.
Strong, independent, quantitative genetic control of the timing of vegetative phase change and first flowering in eucalyptus globulus ssp. globulus (Tasmanian blue gum)
Leaf Barriers to Fungal Colonization and Shredders (Tipula lateralis) Consumption of Decomposing Eucalyptus globulus.
Ontogenetic differences in mesophyll structure and chlorophyll distribution in Eucalyptus globulus ssp. globulus.
Eucalyptus has a functional equivalent of the Arabidopsis floral meristem identity gene LEAFY.
Evaluating a simple radiation/dry matter conversion model using data from Eucalyptus globulus plantations in Western Australia.
Leaf water relations of Eucalyptus globulus ssp. globulus and E. nitens: seasonal, drought and species effects.
In vitro evaluation of medicinal plant extracts against Pestalotiopsis mangiferae.
Photosynthetic temperature responses of Eucalyptus globulus and Eucalyptus nitens.
Conductimetric analysis of the ion binding properties of three leaf extracts of chestnut (Castanea sativa), Eucalyptus (Eucalyptus globulus) and oak (Quercus robur).
Role of nitrogen remobilization from old leaves for new leaf growth of Eucalyptus globulus seedlings.
Comparative analysis of allelopathic effects produced by four forestry species during decomposition process in their soils in Galicia (NW Spain).
Genotypic differences in water use efficiency and (13)C discrimination in Eucalyptus globulus.
Photosynthetic capacity of leaves of Eucalyptus globulus (Labill.) growing in the field with different nutrient and water supplies.
Control of growth of juvenile leaves of Eucalyptus globulus: effects of leaf age.
Leaf growth of Eucalyptus globulus seedlings under water deficit.
Water and nutrient supply regimes and the water relations of juvenile leaves of Eucalyptus globulus.
Growth and water relations of seedlings of two subspecies of Eucalyptus globulus.
The thermal conductivity of leaves.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.4100
MedlinePlusSupp:View
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:EUCALYPTUS OIL

Suppliers

Absolute Cosmetic Essentials Albert Vieille SAS
Ambles Nature et Chimie Anhui Haibei
Aroma Aromatics & Flavours Aromatic and Allied Chemicals
Astral Extracts Atlantic Chemicals
Augustus Oils Azelis UK
Berjé Biolandes Parfumerie
Blue Pacific Flavors BOC Sciences
Bontoux Bristol Botanicals
Camden-Grey Essential Oils Charabot
Charkit Chemical Chemia
Citrus and Allied Essences Creatingperfume.com
De Monchy Aromatics Diffusions Aromatiques
Dongguan Meiherb Biotech Down Under Enterprises
ECSA Chemicals Elixens America
Ernesto Ventós Esencias Martínez Lozano
Excellentia International F. P. Aromatics Singapore
fnfsurplus.com Frey + Lau
Fuzhou Farwell Garcia Palomo Essences
Gem Aromatics George Uhe Company
Global Essence Golden Spice
Hermitage Oils Indenta Group
India Essential Oils Indo World Trading
Indukern F&F Jiangyin Healthway
John Kellys (London) K.L. Koh Enterprise
Kanta Enterprises Keva
Lionel Hitchen Lluch Essence
M&U International Mentha & Allied Products
Moellhausen Natural & Essential Oils
O'Laughlin Industries Odowell Co.,ltd
OQEMA Payand Betrand
Pearlchem Corporation Penta International
PerfumersWorld Phoenix Aromas & Essential Oils
Plants Power Primechem
Prinova Prodasynth
Quimdis R C Treatt & Co Ltd
Reincke & Fichtner Robertet
Sensient Flavor and Fragrances Sigma-Aldrich
Silver Fern Chemical Silverline Chemicals
SRS Aromatics Sunaux International
Taytonn ASCC The John D. Walsh Company
The Lebermuth Company The Lermond Company
The Perfumers Apprentice The Perfumery
Ultra International Ungerer & Company
United International Vevy Europe
Vigon International Xiamen Doingcom Chemical
Zanos Augustus Oils Ltd
Azelis UK Ltd. Berje Inc.
Bontoux SAS Charkit Chemical Corporation
Elixens America, Inc. Global Essence Inc.
Hermitage Oils / Neroli S.R.L. Indukern, S.A. F&F Ingredients Division
Jiangyin Healthway International Trade Co., Ltd Lluch Essence S.L.
Esencias Martinez Lozano S.A. M&U International LLC
Moellhausen S.P.A. O'Laughlin Industries Inc.
Penta International Corporation PerfumersWorld Ltd.
Anhui Primechem Co., Ltd. Robertet, Inc.
SRS Aromatics Ltd Taytonn ASCC Pte Ltd
The John D. Walsh Company, Inc R C Treatt and Co Ltd
Ultra International Limited Qingdao Free Trade Zone United International Co Ltd
Ernesto Ventós S.A. Zanos Ltd.

PhysChem Properties

Material listed in food chemical codex Yes
Specific gravity @ 25 °C
Pounds per Gallon 7.531 to 7.697
Refractive Index 1.458 to 1.465 @ 20 °C
Vapor Pressure 0.95 mmHg @ 25 °C
Flash Point TCC Value 48.89 °C TCC
Shelf life 24 months (or longer if stored properly.)
Storage notes Store in cool, dry place in tightly sealed containers, protected from heat and light.
Solubility
alcohol Yes
paraffin oil Yes
water, slightly Yes
water, 332.1 mg/L @ 25 °C (est) Yes
water No
Stability
bath foam Unspecified
cream Unspecified
lipstick Unspecified
lotion Unspecified
non-discoloring in most media Unspecified
shampoo Unspecified
soap Unspecified

Organoleptic Properties

Odor Type: Herbal
herbal, eucalyptus, camphoreous, medicinal
Odor strength high , recommend smelling in a 10.00 % solution or less
Substantivity < 4
Luebke, William tgsc, (1992) At 10.00 % in dipropylene glycol. herbal eucalyptol camphor
Flavor Type: Herbal
eucalyptus, herbal
General comment Eucalyptus

Occurrences

Potential Uses

Applications
Odor purposes Agrumen aldehyde, Ajowan, Amyris, Angelica, Arnica flower, Azalea, Baby powder, Balsam, Basil oil replacer, Bayberry, Bayberry, Cajeput, Calamus oil replacer, Camphor tree bark, Caraway seed, Cardamom oil replacer, Carrot seed, Celery, Chamomile, Chrysanthemum, Cilantro, Cistus, Clary sage oil replacer, Copaiba balsam, Coriander, Coronilla, Cranberry, Cubeb, Cypress oil replacer, Deertongue absolute replacer, Eucalyptus oil replacer, Evergreen, Fennel, Fig, Fir balsam, Fir needle oil replacer, Flouve, Forest, Galbanum, Genet, Ginger white ginger, Gingergrass, Guaiacwood, Gurjun balsam, Habuba, Heather, Herbal, Hollyberry, Hop, Hyssop, Incense, Ivy, Labdanum, Lavandin, Lavender, Lavender flower, Lavender spike lavender, Lovage root, Marigold, Marjoram, Mastic oil replacer, Melissa oil replacer, Myrtle oil replacer, Niaouli, Opoponax, Oregano, Parsley leaf, Pine, Pine forest, Pine needle, Pine scotch pine, Pinion, Reseda, Rosemary, Rue, Saffron, Savin, Spruce, Sweet grass, Tagete oil replacer, Tansy oil replacer, Tea green tea, Thyme oil white replacer, Tolu balsam, Valerian, Vetiver, Witch hazel, Woodruff, Woody, Yerba mate, Yew, Zdravetz
Flavoring purposes Ajowan, Angelica, Cajeput, Camphor tree bark, Capsicum, Caraway seed, Carrot, Carrot seed, Cilantro, Cistus, Copaiba balsam, Coriander, Cranberry, Cubeb, Fig, Gin, Guaiacwood, Herbal, Hyssop, Lavender flower, Lavender spike lavender, Lovage root, Marigold, Marjoram, Parsley leaf, Pine needle, Pine scotch pine, Rue, Savin, Spruce, Tansy oil replacer, Tea black tea, Tea darjeeling tea, Tea green tea, Tea herbal tea, Tea jasmin tea, Tea lemon tea, Valerian, Yerba mate, Zdravetz
Other purposes Aromatic, Fruity, Spicy
Cosmetic purposes Perfuming agents, Skin conditioning

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xn N - Harmful, Dangerous for the environment.
R 10 - Flammable.
R 38 - Irritating to skin.
R 43 - May cause sensitisation by skin contact.
R 51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R 65 - Harmful: may cause lung damage if swallowed.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet.
S 62 - If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Flammable liquids (Category 3), H226
Aspiration hazard (Category 1), H304
Skin irritation (Category 2), H315
Skin sensitisation (Category 1), H317
Acute aquatic toxicity (Category 2), H401
Chronic aquatic toxicity (Category 2), H411
GHS Label elements, including precautionary statements
Pictogramflame.jpgexclamation-mark.jpghealth-hazard.jpgenvironment.jpg
Signal word Danger
Hazard statement(s)
H226 - Flammable liquid and vapour
H304 - May be fatal if swallowed and enters airways
H315 - Causes skin irritation
H317 - May cause an allergic skin reaction
H401 - Toxic to aquatic life
H411 - Toxic to aquatic life with long lasting effects
Precautionary statement(s)
P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 - Keep container tightly closed.
P240 - Ground/bond container and receiving equipment.
P241 - Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 - Use only non-sparking tools.
P243 - Take precautionary measures against static discharge.
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 - Wash skin thouroughly after handling.
P272 - Contaminated work clothing should not be allowed out of the workplace.
P273 - Avoid release to the environment.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P331 - Do NOT induce vomiting.
P333 + P313 - IF SKIN irritation or rash occurs: Get medical advice/attention.
P362 - Take off contaminated clothing and wash before reuse.
P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction.
P391 - Collect spillage. Hazardous to the aquatic environment
P403 + P235 - Store in a well-ventilated place. Keep cool.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
oral-rat LD50 2480 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 107, 1975.

oral-rabbit LD50 7031 mg/kg
Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.

intraperitoneal-rat LD50 1200 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 743, 1978.

Dermal Toxicity:
skin-rabbit LD50 2480 mg/kg
Food and Chemical Toxicology. Vol. 26, Pg. 323, 1988.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for eucalyptus globulus oil usage levels up to:
20.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -76.00000
beverages(nonalcoholic): -1.70000
beverages(alcoholic): -1.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.5000050.00000
fruit ices: 0.5000050.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -130.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8000-48-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1993
WGK Germany:2
eucalyptus globulus leaf oil
Chemidplus:0008000484
RTECS:LE2530000 for cas# 8000-48-4