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    General Material Information
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hop oil

General Material Information

Trivial Name hop oil
Short Description volatile oil obtained from the freshly dried membranous cones of the female plants of the hops, humulus lupulus l., cannabidaceae
CAS Number 8007-04-3
FEMA Number 2580
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8007-04-3 ; HOPS, OIL (HUMULUS LUPULUS L.)
Synonyms
  • fructus lupuli oil
  • hops oils
  • humulus lupulus oil
  • humulus oil
  • volatile oil obtained from the freshly dried membranous cones of the female plants of the hops, humulus lupulus l., cannabidaceae
  • humulus lupulus l. oil

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Literature & References

humulus lupulus l. oil
Canada Domestic Sub. List:8007-04-3
Pubchem (sid):135306977
Publications by PubMed
Quantitative trait loci in hop (Humulus lupulus L.) reveal complex genetic architecture underlying variation in sex, yield and cone chemistry.
Effect of linalool as a component of Humulus lupulus on doxorubicin-induced antitumor activity.
Headspace solid-phase microextraction combined with mass spectrometry as a powerful analytical tool for profiling the terpenoid metabolomic pattern of hop-essential oil derived from Saaz variety.
A dietary supplement to improve the quality of sleep: a randomized placebo controlled trial.
Heterodimeric geranyl(geranyl)diphosphate synthase from hop (Humulus lupulus) and the evolution of monoterpene biosynthesis.
Effects of powdery mildew fungicide programs on twospotted spider mite (Acari: Tetranychidae), hop aphid (Hemiptera: Aphididae), and their natural enemies in hop yards.
Comparison of odor-active compounds in the spicy fraction of hop (Humulus lupulus L.) essential oil from four different varieties.
A TLC bioautographic assay for the detection of nitrofurantoin resistance reversal compound.
The combination of gas chromatography-olfactometry and multidimensional gas chromatography for the characterisation of essential oils.
Sedating effects of Humulus lupulus L. extracts.
Effects of beer and hop on ionotropic gamma-aminobutyric acid receptors.
Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.).
Characterization of varietal differences in essential oil components of hops (Humulus lupulus) by SFC-FTIR spectroscopy.
Direct thermal desorption-gas chromatography and gas chromatography-mass spectrometry profiling of hop (Humulus lupulus L.) essential oils in support of varietal characterization.
Fractionation by SFE and microcolumn analysis of the essential oil and the bitter principles of hops.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 7.224 to 7.425
Flash Point TCC Value 47.78 °C TCC
Solubility
alcohol Yes
water, 0.01396 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Herbal
sharp, green, spicy, sweet, beer, hops, herbal, floral, fruity, tagette, terpenic, woody, vegetable
Odor strength medium , recommend smelling in a 1.00 % solution or less
Substantivity 52 hour(s) at 100.00 %
Luebke, William tgsc, (1989) At 1.00 % in dipropylene glycol. sharp green spicy sweet beer herbal
Mosciano, Gerard P&F 24, No. 1, 13, (1999) At 1.00 %. Floral, sweet, fruity, slightly green tagette, with a herbaceous, terpy and woody vegetative note
Flavor Type: Herbal
floral, fruity, herbal, woody, citrus, terpenic, beer, tropical, sweet
Luebke, William tgsc, (1989) Floral fruity herbal woody citrus terpenic beer tropical
Mosciano, Gerard P&F 24, No. 1, 13, (1999) At 5.00 ppm. Floral, sweet, fruity, woody, citrus terpy with a tropical nuance

Occurrences

Potential Uses

Applications
Odor purposes Apricot, Chypre, Country meadow, Fern, Green, Leather russian leather, Mango, Tobacco
Flavoring purposes Beer, Molasses, Tomato, Tonic, Tropical
Other purposes Mitsouko
Cosmetic purposes Fragrance, Perfuming agents, Tonic

Safety Information

Safety information

European information :
Most important hazard(s):
Xi - Irritant
R 10 - Flammable.
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 3500 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

oral-rat LD50 2700 mg/kg
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
geraniol Max. Found: 0.2 % and Reason: Sensitization
Recommendation for hop oil usage levels up to:
0.3000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -2.90000
beverages(nonalcoholic): -1.70000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -2.20000
condiments / relishes: 20.0000035.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.70000
fruit ices: -1.70000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -2.50000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
EPA Substance Registry Services (TSCA):8007-04-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
humulus lupulus l. oil
Chemidplus:0008007043