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ferula assa-foetida gum oil

General Material Information

Preferred name ferula assa-foetida gum oil
Trivial Name Oils, asafetida
Short Description essential oil obtained from the gum of the asafetida, ferula assa-foetida l., apiaceae
CAS Number 72869-70-6
FEMA Number 2108
FDA UNII 4LHT1248GU
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 72869-70-6 ; ASAFETIDA, OIL (FERULA ASSAFOETIDA L.)
Synonyms
  • asa foetida oil
  • asafetida oil
  • asafoetida oil
  • asafoetida oil english distilled SAS
  • assafetida oil
  • essential oil obtained from the gum of the asafetida, ferula assa-foetida l., apiaceae
  • ferula asafoetida oil
  • ferula foetida gum oil
  • scorodosma foetidum gum oil
  • ferula asafoetida l. oil
  • Oils, asafetida

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Literature & References

ferula asafoetida l. oil
Canada Domestic Sub. List:72869-70-6
Pubchem (sid):135320926
Publications by PubMed
Impact of Herbal Medicines like Nigella sativa, Trigonella foenum-graecum, and Ferula asafoetida, on Cytochrome P450 2C11 Gene Expression in Rat Liver.
Antimicrobial activity of selected Iranian medicinal plants against a broad spectrum of pathogenic and drug multiresistant micro-organisms.
The Relaxant Effect of Seed's Essential Oil and Oleo-Gum-Resin of Ferula Assa-Foetida on Isolated Rat's Ileum.
Cytotoxic properties of some medicinal plant extracts from mazandaran, iran.
Oleo gum resin of Ferula assa-foetida L. ameliorates peripheral neuropathy in mice.
Relaxant effects of asafoetida extract and its constituent umbelliprenin on guinea-pig tracheal smooth muscle.
Double edged effect of gum-resin of ferula assa-foetida on lifespan of neurons.
Double edged effect of gum-resin of ferula assa-foetida on lifespan of neurons.
Tertiary combination of freeze-dried urine of Indian breeds of cow with plant products against snail Lymnaea acuminata.
Use of complementary and alternative medicine for children: a parents' perspective.
Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida.
Effects of Cymbopogon citratus and Ferula assa-foetida extracts on glutamate-induced neurotoxicity.
Chemical composition, antioxidant and antimicrobial activities of essential oil obtained from Ferula assa-foetida oleo-gum-resin: effect of collection time.
New claims in folk veterinary medicines from Uttar Pradesh, India.
Ferula asafoetida: Traditional uses and pharmacological activity.
Inhibitory effect of Ferula asafoetida L. (Umbelliferae) on Blastocystis sp. subtype 3 growth in vitro.
Evaluation of the effect of Ferula asafoetida Linn. gum extract on learning and memory in Wistar rats.
Dietary agents in the prevention of alcohol-induced hepatotoxicty: preclinical observations.
Bait formulations of molluscicides and their effects on biochemical changes in the ovotestis of snail Lymnaea acuminata (Mollusca; Gastropoda:Lymnaeidae).
Combination of molluscicides with attractant carbohydrates and amino acids in bait formulation against the snail Lymnaea acuminata.
Biological activity of some plant essential oils against Varroa destructor (Acari: Varroidae), an ectoparasitic mite of Apis mellifera (Hymenoptera: Apidae).
Asimafoetidnol: a new sesquiterpenoid coumarin from the gum resin of Ferula assa-foetida.
Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin)-a review.
Galbanic acid, a cytotoxic sesquiterpene from the gum resin of Ferula asafoetida, blocks protein farnesyltransferase.
Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida.
Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata.
Development and evaluation of hepatoprotective polyherbal formulation containing some indigenous medicinal plants.
Galbanic acid from Ferula szowitsiana enhanced the antibacterial activity of penicillin G and cephalexin against Staphylococcus aureus.
A new ester isolated from Ferula assa-foetida L.
Molluscicidal activity of Ferula asafoetida, Syzygium aromaticum and Carum carvi and their active components against the snail Lymnaea acuminata.
Larvicidal activity of plant extracts used alone and in combination with known synthetic larvicidal agents against Aedes aegypti.
Antispasmodic and hypotensive effects of Ferula asafoetida gum extract.
Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
Sesquiterpene coumarins from the roots of Ferula assa-foetida.
Reversal of aflatoxin induced liver damage by turmeric and curcumin.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Solubility
water, 5510 mg/L @ 25 °C (est) Yes

Organoleptic Properties

Odor Type: Alliaceous
sulfurous, alliaceous, savory, onion green onion, vegetable, resinous
General comment At 0.10 % in propylene glycol. sulfury alliaceous savory green onion vegetable
Mosciano, Gerard P&F 21, No. 4, 51, (1996) Sulfureous, alliaceous, savory, green onion and resinous with a vegetative note
Flavor Type: Alliaceous
alliaceous, sulfurous, savory, metallic, woody, green, pungent
Mosciano, Gerard P&F 21, No. 4, 51, (1996) At 2.50 ppm. Alliaceous, sulfureous, savory, metallic, woody, green and pungent

Occurrences

Potential Uses

Applications
Odor purposes Balsam, Fruit, Spice
Flavoring purposes Garlic, Onion, Shallot
Cosmetic purposes Perfuming agents

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for ferula assa-foetida gum oil usage levels up to:
0.0100 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -1.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -10.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 1.0000015.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):72869-70-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
ferula asafoetida l. oil
Chemidplus:0072869706