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red thyme oil spain

General Material Information

Preferred name red thyme oil spain
Trivial Name Thyme oil
Short Description red thymus vulgaris oil spain
CAS Number 8007-46-3
FEMA Number 3064
FDA UNII 2UK410MY6B
MDL MFCD00148640
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8007-46-3 ; THYME OIL (THYMUS VULGARIS L. AND T. ZYGIS VAR. GRACILIS BOISS.)
Synonyms
  • oil thyme red spanish 40/45%
  • red thyme EO
  • thyme essential oil: white/red
  • thyme oil red
  • thyme oil red bio
  • thyme oil red spanish 40/45% FCC
  • thyme oil red, spanish
  • thyme oil, red
  • thyme red EO
  • thyme red ess. oil (for fragrance) (Robertet)
  • thyme red TICO 18 (Takasago)
  • red thymus vulgaris oil spain
  • thymus vulgaris l. oil red
  • Thyme oil
  • Oils, thyme
  • Oils, essential, thyme, Thymus vulgaris
  • Essential oils, thyme, Thymus vulgaris
  • Oil of Thyme
  • Thymus vulgaris oils
  • Thyme leaf oil
  • Oleum Thymi Vulgaris
  • Thymus vulgaris essential oils
  • Thymus vulgaris essential oil
  • Oleum thymi
  • BioZell

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Literature & References

thymus vulgaris l. oil red
Canada Domestic Sub. List:8007-46-3
Pubchem (sid):135330310
Publications by PubMed
Antimicrobial effect against different bacterial strains and bacterial adaptation to essential oils used as feed additives.
Characterization of Essential Oil Components from Aromatic Plants that Grow Wild in the "Piana del Sele" (Salerno, Southern Italy) using Gas Chromatography-Mass Spectrometry.
Comparative inhibitory effects of Thymus vulgaris L. essential oil against Staphylococcus aureus, Listeria monocytogenes and mesophilic starter co-culture in cheese-mimicking models.
In vitro activity of essential oils extracted from condiments against fluconazole-resistant and -sensitive Candida glabrata.
Antifungal Effect of Essential Oils against Fusarium Keratitis Isolates.
Studies on Chemical Composition, Antimicrobial and Antioxidant Activities of Five Thymus vulgaris L. Essential Oils.
Alternative treatment of vaginal infections - in vitro antimicrobial and toxic effects of Coriandrum sativum L. and Thymus vulgaris L. essential oils.
Analysis and evaluation of antibacterial effects of new herbal formulas, AP-001 and AP-002, against Escherichia coli O157:H7.
The influence of purge times on the yields of essential oil components extracted from plants by pressurized liquid extraction.
Modulatory effects of thymol and carvacrol on inflammatory transcription factors in lipopolysaccharide-treated macrophages.
An investigation of the bactericidal activity of selected essential oils to Aeromonas spp.
Antimicrobial and antioxidant activities and chemical characterization of essential oils of Thymusvulgaris, Rosmarinus officinalis, and Origanum majorana from northeastern México.
Antifungal activity of various essential oils against Rhizoctonia solani and Macrophomina phaseolina as major bean pathogens.
Enhancing stability of essential oils by microencapsulation for preservation of button mushroom during postharvest.
Antifungal properties and inhibitory effects upon aflatoxin production of Thymus vulgaris L. by Aspergillus flavus Link.
Extraction of thymol from different varieties of thyme plants using green solvents.
Growth performance and antioxidant enzyme activities in rainbow trout (Oncorhynchus mykiss) juveniles fed diets supplemented with sage, mint and thyme oils.
Antimicrobial activity of essential oils of Thymus vulgaris and Origanum vulgare on phytopathogenic strains isolated from soybean.
Thymus vulgaris essential oil and thymol against Alternaria alternata (Fr.) Keissler: effects on growth, viability, early infection and cellular mode of action.
Carum copticum and Thymus vulgaris oils inhibit virulence in Trichophyton rubrum and Aspergillus spp.
Short communication: an in vitro assessment of the antibacterial activity of plant-derived oils.
Effects of thyme as a feed additive in broiler chickens on thymol in gut contents, blood plasma, liver and muscle.
Does antioxidant properties of the main component of essential oil reflect its antioxidant properties? The comparison of antioxidant properties of essential oils and their main components.
Antibacterial activity against Clostridium genus and antiradical activity of the essential oils from different origin.
Comparative effect of thymus vulgaris and ibuprofen on primary dysmenorrhea: A triple-blind clinical study.
Activity of Thymus vulgaris essential oil against Anisakis larvae.
Impact of shortwave ultraviolet (UV-C) radiation on the antioxidant activity of thyme (Thymus vulgaris L.).
Unravelling the complex antimicrobial interactions of essential oils--the case of Thymus vulgaris (thyme).
Hepatoprotective Effect of Pretreatment with Thymus vulgaris Essential Oil in Experimental Model of Acetaminophen-Induced Injury.
Prospective evaluation of potential toxicity of repeated doses of Thymus vulgaris L. extracts in rats by means of clinical chemistry, histopathology and NMR-based metabonomic approach.
Prolonging storage time of baby ginger by using a sand-based storage medium and essential oil treatment.
Effect of thyme essential oil and selenium on intestine integrity and antioxidant status of broilers.
Thymus vulgaris essential oil: chemical composition and antimicrobial activity.
Reduction of Aeromonas hidrophyla biofilm on stainless stell surface by essential oils.
The effect of vacuum packaging, EDTA, oregano and thyme oils on the microbiological quality of chicken's breast.
Lethal and sublethal effects of four essential oils on the egg parasitoids Trissolcus basalis.
Efficacy of plant essential oils on postharvest control of rots caused by fungi on different stone fruits in vivo.
The enhancement of antioxidant compounds extracted from Thymus vulgaris using enzymes and the effect of extracting solvent.
Stereochemical mechanism of two sabinene hydrate synthases forming antipodal monoterpenes in thyme (Thymus vulgaris).
Evaluation of the control ability of five essential oils against Aspergillus section Nigri growth and ochratoxin A accumulation in peanut meal extract agar conditioned at different water activities levels.
Chemical composition, olfactory analysis and antibacterial activity of Thymus vulgaris chemotypes geraniol, 4-thujanol/terpinen-4-ol, thymol and linalool cultivated in southern France.
Extraction of volatile oil from aromatic plants with supercritical carbon dioxide: experiments and modeling.
Repellency of essential oils to Frankliniella occidentalis (Thysanoptera: Thripidae) as affected by type of oil and polymer release.
Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response.
The effects of thyme (Thymus vulgaris) and rosemary (Rosmarinus officinalis) essential oils on Brochothrix thermosphacta and on the shelf life of beef packaged in high-oxygen modified atmosphere.
Antioxidative effect of thyme (Thymus vulgaris) in sunflower oil.
Effects of Thyme Extract Oils (from Thymus vulgaris, Thymus zygis, and Thymus hyemalis) on Cytokine Production and Gene Expression of oxLDL-Stimulated THP-1-Macrophages.
In vitro inhibitory activity of essential oil vapors against Ascosphaera apis.
Bioassay-guided fractionation of a thymol-deprived hydrophilic thyme extract and its antispasmodic effect.
In vitro control of post-harvest fruit rot fungi by some plant essential oil components.
Investigation of the chemical composition-antibacterial activity relationship of essential oils by chemometric methods.
[Extraction and analysis of chemical components of essential oil in Thymus vulgaris of tissue culture].
An investigation on characteristics of rainbow trout coated using chitosan assisted with thyme essential oil.
Antifungal activity of Thymus vulgaris L. essential oil and its constituent phytochemicals against Rhizopus oryzae: interaction with ergosterol.
[Sensitivity assessment of thyme and lavender essential oils against clinical strains of Escherichia coli for their resistance].
The antimicrobial activity of thyme essential oil against multidrug resistant clinical bacterial strains.
In vitro effects of some herbs used in Egyptian traditional medicine on viability of protoscolices of hydatid cysts.
Antimicrobial, antioxidant, and anti-inflammatory activities of essential oils from five selected herbs.
Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds.
Seasonal variation in essential oil yield and composition from Thymus vulgaris L. during different growth stages in the south of Jordan.
Chemical characterization (GC/MS and NMR Fingerprinting) and bioactivities of South-African Pelargonium capitatum (L.) L' Her. (Geraniaceae) essential oil.
Antioxidant properties of Thymus vulgaris oil against aflatoxin-induce oxidative stress in male rats.
Composition and biological activity of essential oils from Labiatae against Nezara viridula (Hemiptera: Pentatomidae) soybean pest.
Anticandida activity of the marketed essential oil of Thymus vulgaris L and its concomitant action with amphotericin B.
Evaluation of commercial essential oil samples on the growth of postharvest pathogen Monilinia fructicola (G. Winter) Honey.
Cytotoxicity of Thymus vulgaris essential oil towards human oral cavity squamous cell carcinoma.
Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model.
A validated high performance liquid chromatography method for the analysis of thymol and carvacrol in Thymus vulgaris L. volatile oil.
Herbicidal activity of volatiles from coriander, winter savory, cotton lavender, and thyme isolated by hydrodistillation and supercritical fluid extraction.
An attempt of postharvest orange fruit rot control using essential oils from Mediterranean plants.
Biodegradable gelatin-chitosan films incorporated with essential oils as antimicrobial agents for fish preservation.
Chemical composition and antioxidant and anti-Listeria activities of essential oils obtained from some Egyptian plants.
Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.
Evaluation of the toxicity of 17 essential oils against Choristoneura rosaceana (Lepidoptera: Tortricidae) and Trichoplusia ni (Lepidoptera: Noctuidae).
Composition and antioxidant activity of Thymus vulgaris volatiles: comparison between supercritical fluid extraction and hydrodistillation.
Effect of Enterococcus faecium AL41 and Thymus vulgaris essential oil on small intestine integrity and antioxidative status of laying hens.
Matrix solid-phase dispersion (MSPD) in chromatographic analysis of essential oils in herbs.
Mosquitocidal activities of thyme oils (Thymus vulgaris L.) against Culex quinquefasciatus (Diptera: Culicidae).
Static and dynamic superheated water extraction of essential oil components from Thymus vulgaris L.
Intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.
Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA).
Additive antimicrobial [corrected] effects of the active components of the essential oil of Thymus vulgaris--chemotype carvacrol.
The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials.
Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities.
In vitro activity of essential oils extracted from plants used as spices against fluconazole-resistant and fluconazole-susceptible Candida spp.
Inhibitory effects of Iranian Thymus vulgaris extracts on in vitro growth of Entamoeba histolytica.
Comparison of microwave-assisted hydrodistillation withthe traditional hydrodistillation method in the extractionof essential oils from Thymus vulgaris L.
Antioxidative properties of Thymus vulgaris leaves: comparison of different extracts and essential oil chemotypes.
Application of PLE for the determination of essential oil components from Thymus vulgaris L.
Antifungal activity of the essential oil of Thymus vulgaris L. and thymol on experimentally induced dermatomycoses.
Antibacterial efficiency of Spanish Satureja montana essential oil against Listeria monocytogenes among natural flora in minced pork.
Acaricidal activity of Thymus vulgaris oil and its main components against Tyrophagus putrescentiae, a stored food mite.
Evaluation of antibacterial activity of selected Iranian essential oils against Staphylococcus aureus and Escherichia coli in nutrient broth medium.
Nematicidal and Propagation Activities of Thyme Red and White Oil Compounds toward Bursaphelenchus xylophilus (Nematoda: Parasitaphelenchidae).
Comparison of different extraction methods for the determination of essential oils and related compounds from aromatic plants and optimization of solid-phase microextraction/gas chromatography.
Antifungal activity of thyme (Thymus vulgaris L.) essential oil and thymol against moulds from damp dwellings.
In vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives thymoquinone and thymohydroquinone.
[Inhibition of Paenibacillus larvae employing a mixture of essential oils and thymol].
Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure.
Deuterium/hydrogen ratio analysis of thymol, carvacrol, gamma-terpinene and p-cymene in thyme, savory and oregano essential oils by gas chromatography-pyrolysis-isotope ratio mass spectrometry.
Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putida strain isolated from meat.
Testing of the palatability of Thymus vulgaris L. and Origanum vulgare L. as flavouring feed additive for weaner pigs on the basis of a choice experiment.
Characterization of the volatile composition of essential oils of some lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils.
Effects of Thymus vulgaris L. as feed additive in piglets and against haemolytic E. coli in vitro.
Volatile components and key odorants of fennel (Foeniculum vulgare Mill.) and thyme (Thymus vulgaris L.) oil extracts obtained by simultaneous distillation-extraction and supercritical fluid extraction.
Monoterpenes from thyme (Thymus vulgaris) as potential mosquito repellents.
Antifungal effect of various essential oils against Candida albicans. Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris.
RP-HPLC analysis of the phenolic compounds of plant extracts. investigation of their antioxidant capacity and antimicrobial activity.
Antimicrobial activity of five essential oils against origin strains of the Enterobacteriaceae family.
Solvent-free microwave extraction of essential oil from aromatic herbs: comparison with conventional hydro-distillation.
Do co-occurring plant species adapt to one another? The response of Bromus erectus to the presence of different Thymus vulgaris chemotypes.
Evaluation of five essential oils from aromatic plants of Cameroon for controlling food spoilage and mycotoxin producing fungi.
Effects of the inclusion of Thymus vulgaris L. oil in diets with and without enzymes, on nutrient digestibility in broilers.
Composition and functional properties of the essential oil of amazonian basil, Ocimum micranthum Willd., Labiatae in comparison with commercial essential oils.
Influence of nitrogen fertilizers on the yield and composition of thyme (Thymus vulgaris).
[Anti-Candida albicans activity of essential oils including Lemongrass (Cymbopogon citratus) oil and its component, citral].
Essential oils from Mediterranean lamiaceae as weed germination inhibitors.
Qualitative and quantitative variation in monoterpene co-occurrence and composition in the essential oil of Thymus vulgaris chemotypes.
Antibacterial activity of selected plant essential oils against Escherichia coli O157:H7.
Repellent activities of essential oils and monoterpenes against Culex pipiens pallens.
GC/MS evaluation of thyme (Thymus vulgaris L.) oil composition and variations during the vegetative cycle.
Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method.
Correlation between the chemical and genetic relationships among commercial thyme cultivars.
Acute, sublethal, antifeedant, and synergistic effects of monoterpenoid essential oil compounds on the tobacco cutworm, Spodoptera litura (Lep., Noctuidae).
GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum.
In vitro effect of essential oils and isolated mono- and sesquiterpenes on Leishmania major and Trypanosoma brucei.
Dietary supplementation of thyme (Thymus vulgaris L.) essential oil during the lifetime of the rat: its effects on the antioxidant status in liver, kidney and heart tissues.
Antimicrobial activity of the essential oils of Thymus vulgaris L. measured using a bioimpedometric method.
Evaluation of the preservative properties of Thymus vulgaris essential oil in topically applied formulations under a challenge test.
The effect of the volatile oils of Chenopodium ambrosioides and Thymus vulgaris against the larvae of Lucilia sericata (Meigen).
[Systemic emulsions. 2. Use of different methods of formulation: the effect of essential oils of thyme on stability].
Studies on the genotoxic properties of essential oils with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay.
[Antibacterial action of essential oils extracted from Madagascar plants].
[Composition of volatile oil from Thymus vulgaris and Thumus marshallianus depending on age of leaves and seasons].
[Studies on the variability of content and composition of volatile oil in leaf- and herb-drugs of Thymus vulgaris L].
[Effects of fading on the yield, the main components and the physicochemical properties of the volatile oil from Thymus vulgaris L. II].
[EFFECT OF WILTING ON THE YIELD, CONTENT AND PHYSICO-CHEMICAL STABILITY OF THE PRINCIPAL COMPONENTS OF THE OIL OF THYMUS VULGARIS L].
[The decrease in oil content in the dead leaves of Thymus vulgaris].
Publications by J-Stage
Antimicrobial, Antioxidant, and Anti-Inflammatory Activities of Essential Oils from Five Selected Herbs

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 7.614 to 7.78
Refractive Index 1.495 to 1.505 @ 20 °C
Flash Point TCC Value 55 °C TCC
Solubility
alcohol Yes
glycerin Yes
water, 437.4 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Herbal
herbal, spicy, phenolic, camphoreous, medicinal, aromatic, terpenic
Odor strength high , recommend smelling in a 10.00 % solution or less
Substantivity 172 hour(s) at 100.00 %
Luebke, William tgsc, (1997) At 10.00 % in dipropylene glycol. herbal spicy phenolic camphoreous medicinal aromatic terpenic
Flavor Type: Herbal
herbal, medicinal, camphoreous, aromatic, phenolic, spicy, resinous
Luebke, William tgsc, (1997) Herbal medicinal camphoreous aromatic phenolic spicy resinous

Occurrences

Safety Information

Safety information

European information :
Most important hazard(s):
Xn - Harmful.
R 22 - Harmful if swallowed.
R 34 - Causes burns.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 20/21 - When using do not eat, drink or smoke.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 28 - After contact with skin, wash immediately with plenty of water.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
8 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 2840 mg/kg
Pharmazie. Vol. 14, Pg. 435, 1959.

unreported-mouse LD50 1250 mg/kg
Pharmazie. Vol. 11, Pg. 628, 1956.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 1003, 1974.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
geraniol Max. Found: 0.1 % and Reason: Sensitization
(E)-2-hexen-1-al Max. Found: trace to
eugenol Max. Found: 0.1 % and Reason: Sensitization
methyl eugenol Max. Found: 0.03 % and Reason: Sensitization
Recommendation for red thyme oil spain usage levels up to:
2.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: 1.500005.30000
beverages(nonalcoholic): 1.000005.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -100.00000
condiments / relishes: -18.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -20.00000
fruit ices: -20.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 1.0000015.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -33.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -0.13000
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
EPA Substance Registry Services (TSCA):8007-46-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
thymus vulgaris l. oil red
Chemidplus:0008007463
RTECS:XP2000000 for cas# 8007-46-3