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    General Material Information
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cinnamon bark oil ceylon

General Material Information

Preferred name cinnamon bark oil ceylon
Trivial Name Cinnamon bark oil
Short Description volatile oil expressed from the bark of the ceylon cinnamon, cinnamomum zeylanicum, lauraceae
CAS Number 8015-91-6
FEMA Number 2291
FDA UNII E5GY4I6YCZ
MDL MFCD00130805
COE Number 133
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8015-91-6 ; CINNAMON BARK, OIL (CINNAMOMUM SPP.)
Synonyms
  • cinnamomum verum bark oil ceylon
  • cinnamomum zeylanicum bark oil ceylon
  • cinnamon bark ceylan EO
  • cinnamon bark oil 50%
  • cinnamon bark oil 65% (low safrole)
  • cinnamon bark oil ceylan
  • cinnamon bark oil ceylon FCC
  • cinnamon bark oil madagascar FLG (IFF)
  • cinnamon bark oil madagascar organic
  • cinnamon type ceylan ess nat 01
  • oil cinnamon bark ceylon 65%
  • volatile oil expressed from the bark of the ceylon cinnamon, cinnamomum zeylanicum, lauraceae
  • cinnamomum verum bark oil
  • Cinnamon oil
  • Oils, cinnamon
  • Oils, essential, cinnamon
  • Essential oils, cinnamon
  • Oils, essential, cinnamon leaf
  • Essential oils, cinnamon leaf
  • Ceylon cinnamon bark oil
  • Cinnamon bark oil, Ceylon
  • Cinnamon oil, Ceylon
  • Artificial cinnamon oil
  • Cinnamon oil, artificial
  • Oils, Cinnamomum zeylanicum
  • Cinnamomum zeylanicum oil
  • Cinnamon leaf oil
  • Cinnamomum zeylanicum leaf oil
  • Ceylon cinnamon leaf oil
  • Oils, Ceylon cinnamon leaf
  • Cinnamomum zeylanicum bark oil
  • Oils, Ceylon cinnamon bark
  • Cinnamon bark oil
  • Cinnamomum oil
  • Cinnamomum leaf oil
  • Cinnamomum oils
  • Cinnamon bark oils
  • Oleum Cinnamomi

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Literature & References

cinnamomum verum bark oil
Canada Domestic Sub. List:8015-91-6
Pubchem (sid):135346120
Publications by PubMed
Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.
Discovery of a novel anti-cancer agent targeting both topoisomerase I and II in hepatocellular carcinoma Hep 3B cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.
Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo.
Invitro Anti-mycotic Activity of Hydro Alcoholic Extracts of Some Indian Medicinal Plants against Fluconazole Resistant Candida albicans.
Anthelmintic activity of trans-cinnamaldehyde and A- and B-type proanthocyanidins derived from cinnamon (Cinnamomum verum).
Empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria.
Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.
Authentication of true cinnamon (Cinnamon verum) utilising direct analysis in real time (DART)-QToF-MS.
Antibacterial Mode of Action of Cinnamomum verum Bark Essential Oil, Alone and in Combination with Piperacillin, Against a Multi-Drug-Resistant Escherichia coli Strain.
Antimicrobial activity of the bioactive components of essential oils from Pakistani spices against Salmonella and other multi-drug resistant bacteria.
Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States.
Assessment of coumarin levels in ground cinnamon available in the Czech retail market.
Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro.
Functional and ultrastructural changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Cinnamomum verum essential oil.
Comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics.
From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark.
Does the taste matter? Taste and medicinal perceptions associated with five selected herbal drugs among three ethnic groups in West Yorkshire, Northern England.
Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putida strain isolated from meat.
Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume.
Anti-oxidant effects of cinnamon (Cinnamomum verum) bark and greater cardamom (Amomum subulatum) seeds in rats fed high fat diet.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:CINNAMOMUM OILS (INCLUDING CINNAMON AND CASSIA)

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 8.404 to 8.571
Refractive Index 1.573 to 1.591 @ 20 °C
Flash Point TCC Value 71.11 °C TCC
Shelf life 12 months (or longer if stored properly.)
Storage notes Store in cool, dry place in tightly sealed containers, protected from heat and light.
Solubility
alcohol Yes
water, 2150 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Spicy
sweet, spicy, aromatic, fruity, cinnamyl, honey, resinous, woody, warm
Odor strength medium , recommend smelling in a 10.00 % solution or less
Substantivity 372 hour(s) at 100.00 %
Luebke, William tgsc, (1988) At 10.00 % in dipropylene glycol. sweet spicy aromatic fruity aldehydic cinnamyl honey resinous woody
Mosciano, Gerard P&F 19, No. 2, 55, (1994) Sweet, cinnamic, spicy warm, woody and aromatic
Flavor Type: Spicy
spicy, sweet, aromatic, aldehydic, fruity, honey, woody, cinnamon, warm
Luebke, William tgsc, (1988) Spicy sweet aromatic aldehydic fruity honey woody
Mosciano, Gerard P&F 19, No. 2, 55, (1994) At 10.00 ppm. Cinnamon, spicy, woody, warm heat, slight fruity
General comment Spicy sweet aromatic aldehydic fruity honey woody

Occurrences

Safety Information

Safety information

European information :
Most important hazard(s):
Xn - Harmful.
R 21 - Harmful in contact with skin.
R 36/38 - Irritating to skin and eyes.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37 - Wear suitable protective clothing and gloves.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 2650 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 749, 1975.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 749, 1975.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
The prime allergen is Cinnamic aldehyde. The concentration of Cinnamic aldehyde in the finished cosmetic product should not exceed 0.1%.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
eugenol Max. Found: 2.00 % and Reason: Sensitization
benzyl benzoate Max. Found:
benzaldehyde Max. Found:
cinnamyl alcohol Max. Found: 0.3 % and Reason: Sensitization
cinnamaldehyde Max. Found: 75.00 % and Reason: Sensitization
coumarin Max. Found: 0.6 % and Reason: Sensitization
isoeugenol Max. Found: 0.02 % and Reason: Sensitization
ortho-methoxycinnamaldehyde Max. Found: 0.5 % and Reason: Sensitization
safrole Max. Found: 0.2 % and Reason: Carcinogenicity
Recommendation for cinnamon bark oil ceylon usage levels up to:
6.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -110.00000
beverages(nonalcoholic): -5.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -620.00000
condiments / relishes: -25.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -18.00000
fruit ices: -18.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -80.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -50.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8015-91-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
cinnamomum verum bark oil
Chemidplus:0008015916
RTECS:FL6340000 for cas# 8015-91-6