ho leaf oil

Ho leaf oil is a type of essential oil derived from the leaves of the camphor tree, specifically the Cinnamomum camphora (L.) variety linalooliferum, belonging to the Lauraceae family. This oil exhibits a distinctive floral and spicy aroma with underlying woody, herbal, and camphoreous notes, attributed mainly to its high linalool content. It has several synonyms including ho-sho leaf oil, shiu leaf oil, and cinnamomum camphora l. nees se eberm. leaf oil. As a natural botanical extract, ho leaf oil is typically obtained through steam distillation of the fresh or dried leaves. Its complex aromatic profile makes it valuable in the fragrance industry for perfuming agents. The chemical and sensory characteristics of ho leaf oil are documented in scientific databases such as PubChem for reference and further study.

Ho leaf oil occurs naturally in the leaves of the camphor tree species Cinnamomum camphora var. linalooliferum. This botanical source is native to parts of Asia and is cultivated for its valuable essential oils. The oil finds application predominantly as a fragrance agent due to its floral, spicy, and woody aroma nuances. It is utilized in perfuming agents incorporated into products that require complex and rich scent profiles. Standards such as FEMA (US) govern the usage of such fragrance materials, ensuring their appropriate application and safety in consumer products. The oil's aromatic qualities lend themselves to contributing to fragrance accords involving notes like rose, lilac, cedar, and herbal elements.

Ho leaf oil is a liquid with a specific gravity ranging from 0.864 to 0.888 at 25 °C, indicating its density relative to water. Its refractive index varies between 1.46 and 1.468 at 20 °C, reflecting its optical properties influenced by chemical composition. The oil exhibits an optical rotation between -18 to -10 degrees, characteristic of its chiral constituents. It is soluble in alcohol but insoluble in water, a property important for formulation in various solvents. The vapor density is approximately 0.87, and the flash point is around 72 °C (162 °F), classifying it as a combustible liquid which requires careful handling. Shelf life extends at least 24 months when stored in cool, dry, tightly sealed containers protected from heat and light, preferably under nitrogen to preserve stability. The oil maintains stability in various media including creams, shampoos, and soaps without discoloration. These characteristics influence its use and storage in fragrance and cosmetic preparations.

FDA Substances Added to Food (formerly EAFUS):	View
Export Tariff Code:	3301.29.6000
Typical G.C.
Wikipedia:	View
FAO:	BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:	SASSAFRAS OIL

Safety information

European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes. R 43 - May cause sensitisation by skin contact. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Flammable liquids (Category 4), H227 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
GHS Label elements, including precautionary statements
Pictogram
Signal word	Warning
Hazard statement(s)
H227 - Combustible liquid H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation
Precautionary statement(s)
P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P264 - Wash skin thouroughly after handling. P271 - Use only outdoors or in a well-ventilated area. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P302 + P352 - IF ON SKIN: wash with plenty of soap and water. P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P333 + P313 - IF SKIN irritation or rash occurs: Get medical advice/attention. P337 + P313 - IF eye irritation persists: Get medical advice/attention. P362 - Take off contaminated clothing and wash before reuse. P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction. P403 + P233 - Store in a well-ventilated place. Keep container tightly closed. P403 + P235 - Store in a well-ventilated place. Keep cool. P405 - Store locked up. P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
oral-rat LD50 3270 mg/kg SKIN AND APPENDAGES (SKIN): HAIR: OTHER SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: COMA Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 917, 1974.
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Sensitization
IFRA Other Specification:
IFRA fragrance material specification:
	Linalool and natural products known to be rich in linalool, such as bois de rose, coriander or ho wood oil, should only be used when the level of peroxides is kept to the lowest practical level. It is recommended to add antioxidants at the time of production of the raw material. The addition of 0.1% BHT or alpha-tocopherol for example has shown great efficiency. The maximum peroxide level for products in use should be 20 mmol/l.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
methyl eugenol	Max. Found:
geraniol	Max. Found: 0.4 % and Reason: Sensitization
citronellol	Max. Found:
Recommendation for ho leaf oil usage levels up to:
	10.0000 % in the fragrance concentrate.
Recommendation for ho leaf oil flavor usage levels up to:
	not for flavor use.

Safety references

EPA Substance Registry Services (TSCA):8022-91-1

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

cinnamomum camphora l. linalooliferum leaf oil

Chemidplus:0008022911