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    General Material Information
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white sassafras oil

General Material Information

Preferred name white sassafras oil
Trivial Name Oils, sassafras
Short Description sassafras albidum oil
CAS Number 8006-80-2
FDA UNII 78ZX2PFG2Z
MDL MFCD00148252
Synonyms
  • laurus albida oil
  • laurus sassafras oil
  • sassafras albidum oil
  • sassafras albidum var. molle oil
  • sassafras officinalis oil
  • sassafras oil chinese
  • sassafras sassafras oil
  • sassafras variifolium oil
  • sassafras albidum (nuttall) nees oil
  • Oils, sassafras
  • Oil of sassafras
  • Sassafras oil

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Literature & References

sassafras albidum (nuttall) nees oil
Canada Domestic Sub. List:8006-80-2
Pubchem (sid):135355615
Publications by PubMed
Forensic profiling of sassafras oils based on comprehensive two-dimensional gas chromatography.
Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant.
Effect of tree species and end seal on attractiveness and utility of cut bolts to the redbay ambrosia beetle and granulate ambrosia beetle (coleoptera: Curculionidae: Scolytinae).
Safrole-2',3'-oxide induces cytotoxic and genotoxic effects in HepG2 cells and in mice.
Biological reactive intermediates (BRIs) formed from botanical dietary supplements.
Pharmacological characterization of (3-thienylidene)-3,4-methylenedioxybenzoylhydrazide: a novel muscarinic agonist with antihypertensive profile.
A study of impurities in intermediates and 3,4-methylenedioxymethamphetamine (MDMA) samples produced via reductive amination routes.
Inhibition of human cytochrome P450 enzymes by the natural hepatotoxin safrole.
The chemical composition of some Lauraceae essential oils and their antifungal activities.
Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation.
Synthesis and antiplatelet evaluation of novel aryl-sulfonamide derivatives, from natural safrole.
Synthesis and cytotoxic activity of N-substituted thiosemicarbazones of 3-(3,4-methylenedioxy)phenylpropanal.
Liquid chromatographic determination of safrole in sassafras-derived herbal products.
Chemical composition of essential oil from the root bark of Sassafras albidum.
Symptomatic sassafras oil ingestion.
Investigation of the chemical constituents of Brazilian sassafras oil.
An investigation of Brazilian sassafras oil; a comparison with oil of sassafras U.S.P. in regard to taste and odor preference.

Other Information

Export Tariff Code:3301.29.6000
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:SASSAFRAS OIL

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 8.978 to 9.136
Refractive Index 1.533 to 1.537 @ 20 °C
Flash Point TCC Value 107.22 °C TCC
Solubility
water, 75.98 mg/L @ 25 °C (est) Yes

Organoleptic Properties

Odor Type: Spicy
sweet, spicy, fresh, camphoreous, woody, floral, root beer, sarsaparilla
Odor strength medium , recommend smelling in a 1.00 % solution or less
Substantivity 144 hour(s) at 100.00 %
Luebke, William tgsc, (1983) At 1.00 % in dipropylene glycol. sweet spicy fresh camphor woody floral rootbeer

Occurrences

Potential Uses

Applications
Odor purposes Cinnamon, Windsor soap

Safety Information

Safety information

European information :
Most important hazard(s):
T - Toxic.
R 22 - Harmful if swallowed.
R 45 - May cause cancer.
R 68 - Possible risk of irreversible effects.
S 01/02 - Keep locked up and out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 23 - Do not breath vapour.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
S 53 - Avoid exposure - obtain special instructions before use.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1900 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 825, 1982.

oral-man LDLo 83 mg/kg
SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 825, 1982.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
Safrole as such should not be used as a fragrance ingredient; essential oils containing safrole should not be used at a level such that the total concentration of safrole exceeds 0.01% in consumer products. Examples of essential oils with a high safrole content are Sassafras oil (Sassafras officinale Nees& Eberm.), Ocotea Cymbarum oil (Ocotea pretiosa Metz) and certain qualities of Camphor oils. The total concentration of safrole, isosafrole and dihydrosafrole should not exceed 0.01% in consumer products.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
safrole Max. Found: 92.00 % and Reason: Carcinogenicity
Recommendation for white sassafras oil usage levels up to:
4.0000 % in the fragrance concentrate.

Safety references

EPI System: View
Daily Med:search
EPA Substance Registry Services (TSCA):8006-80-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
sassafras albidum (nuttall) nees oil
Chemidplus:0008006802
RTECS:RJ3400000 for cas# 8006-80-2