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General Material Information

Trivial Name anise seed oil
Short Description pimpinella anisum fruit oil
CAS Number 8007-70-3
FEMA Number 2094
ECHA Number 283-872-7
FDA UNII 6Y89129C8H
Beilstein Number 0629884
MDL MFCD00130517
COE Number 336
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8007-70-3 ; ANISE, OIL (PIMPINELLA ANISUM L.)
Synonyms
  • anise ess nat 01
  • anise essential oil
  • anise oil
  • anise oil FCC
  • anise oil FCC natural
  • anise oil food grade
  • anise oil spain
  • anise oil spanish
  • anise oil vietnam
  • anise oil, chinese
  • anise oil, natural
  • anise seed oil (pimpinella anisum)
  • anise star oil FCC
  • aniseed essential oil
  • aniseed oil
  • aniseed oil (pimpinella)
  • aniseed oil organic
  • anisi seed oil
  • pimpinella anisum fruit oil
  • pimpinella anisum seed oil
  • Oils, anise
  • Oils, essential, anise
  • Essential oils, anise
  • Oil of anise
  • Oils, Pimpinella anisum
  • Oils, Pimpinellaanisum fruit
  • Anise fruit oil

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Literature & References

pimpinella anisum fruit oil
Canada Domestic Sub. List:8007-70-3
Pubchem (sid):135339810
Publications by PubMed
Antibacterial activity against Clostridium genus and antiradical activity of the essential oils from different origin.
Ameliorative Effect of Pimpinella anisum Oil on Immunohistochemical and Ultrastuctural Changes of Cerebellum of Albino Rats Induced by Aspartame.
Anti- and pro-lipase activity of selected medicinal, herbal and aquatic plants, and structure elucidation of an anti-lipase compound.
The Study on the Effects of Pimpinella anisum on Relief and Recurrence of Menopausal Hot Flashes.
Efficacy of Iranian traditional medicine in the treatment of epilepsy.
Use of herbal medicines during pregnancy in a group of Palestinian women.
Isolation of terpenoids from Pimpinella anisum essential oil by high-performance counter-current chromatography.
Evaluation of the control ability of five essential oils against Aspergillus section Nigri growth and ochratoxin A accumulation in peanut meal extract agar conditioned at different water activities levels.
Bioactivity of Dianthus caryophyllus, Lepidium sativum, Pimpinella anisum, and Illicium verum essential oils and their major components against the West Nile vector Culex pipiens.
The influence of essential oil of aniseed (Pimpinella anisum, L.) on drug effects on the central nervous system.
Review of Pharmacological Properties and Chemical Constituents of Pimpinella anisum.
Anticonvulsant and neuroprotective effects of Pimpinella anisum in rat brain.
The antimicrobial activity of essential oils and extracts of some medicinal plants grown in Ash-shoubak region - South of Jordan.
Evaluation of effects of Zingiber officinale on salivation in rats.
Exposure of Candida to p-anisaldehyde inhibits its growth and ergosterol biosynthesis.
Survey on medicinal plants and spices used in Beni-Sueif, Upper Egypt.
Antimicrobial activity of Northwestern Mexican plants against Helicobacter pylori.
Resolution and quantification of isomeric fatty acids by silver ion HPLC: fatty acid composition of aniseed oil (Pimpinella anisum, Apiaceae).
Antiviral and immunostimulating effects of lignin-carbohydrate-protein complexes from Pimpinella anisum.
Synergistic and antagonistic interactions of terpenes against Meloidogyne incognita and the nematicidal activity of essential oils from seven plants indigenous to Greece.
Control of the myiasis-producing fly, Lucilia sericata, with Egyptian essential oils.
An attempt of postharvest orange fruit rot control using essential oils from Mediterranean plants.
Phytotoxic activities of Mediterranean essential oils.
Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation.
Ochratoxin A production in aniseed-based media by selected fungal strains and in anise fruits (Pimpinella anisum L.).
Effect of ethnomedicinal plants used in folklore medicine in Jordan as antibiotic resistant inhibitors on Escherichia coli.
Chemistry, antioxidant, antibacterial and antifungal activities of volatile oils and their components.
Microarray analysis of p-anisaldehyde-induced transcriptome of Saccharomyces cerevisiae.
Ethnopharmacy of Turkish-speaking Cypriots in Greater London.
Aqueous extracts of some medicinal plants are as toxic as Imidacloprid to the sweet potato whitefly, Bemisia tabaci.
Chemical compositions and antioxidant properties of essential oils from nine species of Turkish plants obtained by supercritical carbon dioxide extraction and steam distillation.
Screening of antioxidant properties of seven Umbelliferae fruits from Iran.
Self-therapy practices among university students in Palestine: focus on herbal remedies.
Biosynthesis of t-anethole in anise: characterization of t-anol/isoeugenol synthase and an O-methyltransferase specific for a C7-C8 propenyl side chain.
Control of the mushroom phorid fly, Megaselia halterata (Wood), with plant extracts.
The fruit essential oil of Pimpinella anisum L. (Umblliferae) induces neuronal hyperexcitability in snail partly through attenuation of after-hyperpolarization.
Application of poly(dimethylsiloxane) fiber sol-gel coated onto NiTi alloy electrodeposited with zirconium oxide for the determination of organochlorine pesticides in herbal infusions.
Control of Aspergillus section Flavi growth and aflatoxin accumulation by plant essential oils.
Essential oil composition of Pimpinella anisum L. fruits from various European countries.
Extraction of essential oil from Pimpinella anisum using supercritical carbon dioxide and comparison with hydrodistillation.
Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts.
Application of essential oils in maize grain: impact on Aspergillus section Flavi growth parameters and aflatoxin accumulation.
Recovering effects of aqueous extracts of some selected medical plants on the teratogenic effects during the development of D. melanogaster.
Aqueous suspension of anise "Pimpinella anisum" protects rats against chemically induced gastric ulcers.
Effect of gamma irradiation on microbial load and sensory characteristics of aniseed (Pimpinella anisum).
Antispasmodic and relaxant effects of the hidroalcoholic extract of Pimpinella anisum (Apiaceae) on rat anococcygeus smooth muscle.
Bactericidal activity of black pepper, bay leaf, aniseed and coriander against oral isolates.
Repellent activity of five essential oils against Culex pipiens.
Fumigant activity of plant essential oils and components from horseradish (Armoracia rusticana), anise (Pimpinella anisum) and garlic (Allium sativum) oils against Lycoriella ingenua (Diptera: Sciaridae).
Gas chromatographic-mass spectrometric analysis of essential oils from Pimpinella species gathered from Central and Northern Turkey.
Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae).
In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders.
Insecticidal, repellent and oviposition-deterrent activity of selected essential oils against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus.
Molecular evolution of flavonoid dioxygenases in the family Apiaceae.
Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties.
p-Anisaldehyde: acaricidal component of Pimpinella anisum seed oil against the house dust mites Dermatophagoides farinae and Dermatophagoides pteronyssinus.
Aniseed oil increases glucose absorption and reduces urine output in the rat.
Aromatic compound glucosides, alkyl glucoside and glucide from the fruit of anise.
Supercritical extraction of essential oil from aniseed (Pimpinella anisum L) using CO2: solubility, kinetics, and composition data.
Water-soluble constituents of anise: new glucosides of anethole glycol and its related compounds.
Studies on essential oils: part 10; antibacterial activity of volatile oils of some spices.
The effects of fruit essential oil of the Pimpinella anisum on acquisition and expression of morphine induced conditioned place preference in mice.
Relaxant effect of Pimpinella anisum on isolated guinea pig tracheal chains and its possible mechanism(s).
Phenolic content in differentiated tissue cultures of untransformed and Agrobacterium-transformed roots of anise (Pimpinella anisum L.).
The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice.
Biosynthesis of pseudoisoeugenols in tissue cultures of Pimpinella anisum. Phenylalanine ammonia lyase and cinnamic acid 4-hydroxylase activities.
Elicitor-Induced Formation of Coumarin Derivatives in Suspension Cultures of Pimpinella anisum.
Ethnobotanical survey of the medicinal flora used by the Caribs of Guatemala.
A study of four medicinal plant complexes of Mexico and adjacent United States.
Terpene hydrocarbons in Pimpinella anisum L.
Changes of cytokinin nucleotides in an anise cell culture (Pimpinella anisum L.) during growth and embryogenesis.
Effect of exogenous cytokinins on growth and somatic embryogenesis in anise cells (Pimpinella anisum L.).
Endogenous cytokinins during embryogenesis in an anise cell culture (Pimpinella anisum L.).
Isolation and identification of a new, naturally occurring cytokinin (6-benzylaminopurineriboside) from an anise cell culture (Pimpinella anisum L.).
Isolation and quantitation of isopentenyladenosine in an anise cell culture by single-ion monitoring, radioimmunoassay and bioassay.
Loss of competence for glyoxysome formation during somatic embryogenesis in anise (Pimpinella anisum L.) suspension cultures.
Purification and separation of plant gibberellins from their precursors and glucosyl conjugates.
Fatty acid β-oxidation and glyoxylate cycle enzyme activities of induced glyoxysomes from anise suspension cultures.
Quantitation of gibberellins and the metabolism of [(3)H]gibberellin A 1 during somatic embryogenesis in carrot and anise cell cultures.
Fennel and anise as estrogenic agents.
[Isolation and identification of flavon(ol)-O-glycosides in caraway (Carum carvi L.), fennel (Foeniculum vulgare Mill.), anise (Pimpinella anisum L.), and coriander (Coriandrum sativum L.), and of flavon-C-glycosides in anise. I. Phenolics of spices (author's transl)].
Fertilization and fusion of free endosperm nuclei in Pimpinella anisum L.
[The occurrence of cumarins and sterols in tissue-cultures of roots of Anethum graveolens and Pimpinella anisum (author's transl)].
Nectary gland development and functional duration in Pimpinella anisum L.
Publications by J-Stage
Antiviral and Immunostimulating Effects of Lignin-Carbohydrate-Protein Complexes from Pimpinella anisum

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
FDA Listing of Food Additive Status:View
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex Yes
Specific gravity @ 25 °C
Pounds per Gallon 8.155 to 8.238
Refractive Index 1.552 to 1.559 @ 20 °C
Flash Point TCC Value 84.44 °C TCC
Solubility
alcohol Yes
water No
Stability
detergent Unspecified
lipstick Unspecified
lotion Unspecified
non-discoloring in most media Unspecified
powder Unspecified
shampoo Unspecified
soap Unspecified

Organoleptic Properties

Odor Type: Anise
sweet, licorice, anise, resinous, phenolic, herbal
Odor strength medium , recommend smelling in a 10.00 % solution or less
Substantivity 68 hour(s) at 100.00 %
Luebke, William tgsc, (1990) At 10.00 % in dipropylene glycol. sweet licorice anise
Flavor Type: Anise
anise, licorice, fennel, herbal
General comment Anise

Occurrences

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 2250 mg/kg
Food and Cosmetics Toxicology. Vol. 11, Pg. 865, 1973.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 11, Pg. 865, 1973.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
para-anisaldehyde Max. Found: 1.00 % and Reason: Sensitization
estragole Max. Found: 0.3 % and Reason: Sensitization
limits in the finished product for - "leave on the skin contact":
1.0000 % Recommendation.
limits in the finished product for - "wash off the skin contact":
2.0000 % Recommendation.
limits in the finished product for - "no skin contact":
8.0000 % Recommendation.
Recommendation for anise seed oil usage levels up to:
8.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -120.00000
beverages(nonalcoholic): -7.50000
beverages(alcoholic): -45.00000
breakfast cereal: --
cheese: --
chewing gum: -3200.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -67.00000
fruit ices: -67.00000
gelatins / puddings: --
granulated sugar: --
gravies: -65.00000
hard candy: -500.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -65.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

EPA Substance Registry Services (TSCA):8007-70-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
pimpinella anisum fruit oil
Chemidplus:0008007703
EPA/NOAA CAMEO:hazardous materials
RTECS:BZ4200000 for cas# 8007-70-3