We have found 46587 results matching your criteria.
Please wait while we search...
  1. 1.
    General Material Information
  2. 2.
    PhysChem Properties
  3. 3.
    Occurrences
  4. 4.
    Organoleptic Properties
  5. 5.
    Suppliers
  6. 6.
    Potential Uses
  7. 7.
    Regulatory & Documentation
  8. 8.
    Safety Information
  9. 9.
    Other Information
  10. 10.
    Blenders & Components
  11. 11.
    Literature & References

cubeb oil

General Material Information

Preferred name cubeb oil
Trivial Name Oils, cubeb
Short Description essential oil obtained from the unripe fermented ripe fruits of the tailed pepper, piper cubeba l., piperaceae
CAS Number 8007-87-2
FDA UNII HDE20IN4M5
COE Number 131
FDA Mainterm 8007-87-2 ; CUBEB, OIL (PIPER CUBEBA L. F.)
Synonyms
  • cubeb EO
  • cubeb oil FCC
  • essential oil obtained from the unripe fermented ripe fruits of the tailed pepper, piper cubeba l., piperaceae
  • piper cubeba fruit oil
  • Oils, cubeb
  • Oil of cubeb
  • Oils, Pipercubeba

US / EU / FDA / JECFA / FEMA / Scholar / Patents

Google Scholar Start search
Google Books Start search
Google Patents Start search
Perfumer & Flavorists Start search
EU Patents Start search
PubMeb Start search
NCBI Start search

Literature & References

piper cubeba fruit oil
Canada Domestic Sub. List:8007-87-2
Pubchem (sid):135274884
Publications by PubMed
Anticancer activity studies of cubebin isolated from Piper cubeba and its synthetic derivatives.
Evaluation of lignan (-)-cubebin extracted from Piper cubeba on human colon adenocarcinoma cells (HT29).
Cytotoxic activity of Piper cubeba extract in breast cancer cell lines.
Evaluation of the effectiveness of Piper cubeba extract in the amelioration of CCl4-induced liver injuries and oxidative damage in the rodent model.
Biological activities of Zingiber officinale (Zingiberaceae) and Piper cubeba (Piperaceae) essential oils against pulse beetle, Callosobruchus chinensis (Coleoptera: Bruchidae).
In vitro antiparasitic activity and chemical composition of the essential oil obtained from the fruits of Piper cubeba.
Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant.
A comparative study of the modulatory effects of (-)-cubebin on the mutagenicity/recombinogenicity induced by different chemical agents.
The lignan (-)-cubebin inhibits vascular contraction and induces relaxation via nitric oxide activation in isolated rat aorta.
Mutagenicity and antimutagenicity of (-)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays.
Nephroprotective effect of Kabab chini (Piper cubeba) in gentamycin-induced nephrotoxicity.
Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants.
Identification of ambiguous cubeb fruit by DART-MS-based fingerprinting combined with principal component analysis.
Essential and toxic elements in three Pakistan's medicinal fruits (Punica granatum, Ziziphus jujuba and Piper cubeba) analysed by INAA.
In vitro efficacy of the essential oil of Piper cubeba L. (Piperaceae) against Schistosoma mansoni.
Radical scavenging ability of some compounds isolated from Piper cubeba towards free radicals.
Was the famous astronomer Copernicus also a nephrologist.
The effect of the dibenzylbutyrolactolic lignan (-)-cubebin on doxorubicin mutagenicity and recombinogenicity in wing somatic cells of Drosophila melanogaster.
Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts.
Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh.
Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties.
Piper cubeba targets multiple aspects of the androgen-signalling pathway. A potential phytotherapy against prostate cancer growth?
Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens.
(-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats.
Effect of some medicinal plants on plasma antioxidant system and lipid levels in rats.
Metabolite-cytochrome P450 complex formation by methylenedioxyphenyl lignans of Piper cubeba: mechanism-based inhibition.
Potent CYP3A4 inhibitory constituents of Piper cubeba.
Enzymatic and non-enzymatic antioxidants in selected Piper species.
Investigations of anti-inflammatory and antinociceptive activities of Piper cubeba, Physalis angulata and Rosa hybrida.
Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.
[Constituents of Aristolochia triangularis].
Comparison of vegetative anatomy of piperales. I. Juvenile xylem of twigs.
The occurrence of mature fruits of Piper cubeba in recently imported cubeb.
The problem of foreign botanicals.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Optical Rotation -12 to -43
Acid Value 2 max KOH/g
Flash Point TCC Value 82.22 °C TCC
Solubility
alcohol Yes
water, 4.581 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Spicy
fresh, spicy, bois de rose, herbal, peppery, orange bitter orange, woody, minty, smoky
Odor strength medium , recommend smelling in a 10.00 % solution or less
Substantivity 268 hour(s) at 100.00 %
Luebke, William tgsc, (1986) At 10.00 % in dipropylene glycol. fresh spicy bois de rose herbal woody smokey
Flavor Type: Spicy
spicy, peppery, dry, woody, minty, orange rind, amber, sage clary sage
General comment Cubeb

Occurrences

Potential Uses

Applications
Odor purposes Carnation, Pepper, Pepper tree berry, Spice, Woody
Flavoring purposes Pepper tree berry
Cosmetic purposes Perfuming agents

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
cuminaldehyde Max. Found: 0.1 % and Reason: Sensitization
trans-asarone Max. Found: 3.7 % and Reason: Carcinogenicity
safrole Max. Found: 0.05 % and Reason: Carcinogenicity
Recommendation for cubeb oil usage levels up to:
1.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -4.60000
beverages(nonalcoholic): -2.40000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -33.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.25000
fruit ices: -0.25000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -1.80000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 25.0000030.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
EPA Substance Registry Services (TSCA):8007-87-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
piper cubeba fruit oil
Chemidplus:0008007872