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clove leaf oil
General Material Information
| Preferred name | clove leaf oil |
| Trivial Name | Clove leaf oil Madagascar |
| Short Description | essential oil steam-distilled from the leaves of the clove, eugenia caryophyllus, myrtaceae |
| CAS Number | 8000-34-8 |
| Deleted CAS Number | 8015-97-2 |
| FEMA Number | 2325 |
| FDA UNII | Search |
| FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm | 8015-97-2 ; CLOVE LEAF, OIL (EUGENIA SPP.) |
| Synonyms |
|
US / EU / FDA / JECFA / FEMA / Scholar / Patents
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| NCBI | Start search |
Other Information
| FDA Substances Added to Food (formerly EAFUS): | View |
| Export Tariff Code: | 3301.29.5045 |
| Typical G.C. | |
| Wikipedia: | View |
| FAO: | BASIC PRINCIPLES OF STEAM DISTILLATION |
Suppliers
PhysChem Properties
| Material listed in food chemical codex | No |
| Specific gravity | @ 25 °C |
| Pounds per Gallon | 8.621 to 8.704 |
| Refractive Index | 1.53 to 1.538 @ 20 °C |
| Optical Rotation | -2 |
| Flash Point TCC Value | 93.33 °C TCC |
| Shelf life | 24 months (or longer if stored properly.) |
| Storage notes | Store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Solubility | |
| alcohol | Yes |
| fixed oils | Yes |
| isopropyl myristate | Yes |
| paraffin oil, cloudy | Yes |
| propylene glycol | Yes |
| water, 754 mg/L @ 25 °C (est) | Yes |
| water | No |
| glycerin | No |
Organoleptic Properties
| Odor Type: Spicy | |
| spicy, aromatic, woody, balsamic, minty, peppery, phenolic, powdery | |
| Odor strength | medium |
| Substantivity | 116 hour(s) at 100.00 % |
| Luebke, William tgsc, (1987) | At 100.00 %. spicy aromatic woody balsamic minty peppery phenolic powdery |
| Flavor Type: Spicy | |
| spicy, woody, aromatic, balsamic, minty, peppery, medicinal, waxy | |
| Luebke, William tgsc, (1987) | Spicy woody aromatic balsamic minty peppery medicinal waxy |
Occurrences
| (data available) |
Potential Uses
| Applications | |
| Odor purposes | Acacia , Agate , Allspice , Almond , Angel essence , Balsam , Bay rum , Bayberry , Benzoin absolute replacer , Bluebell , Bouquet , Bubble gum , Caraway seed , Carnation , Cassia , Cherry , Cherry blossom , Christmas , Cinnamon , Citrus , Clove , Floral , Florida breeze , Forest , Greenhouse , Herbal , Hollyberry , Honeysuckle , Hovenia , Incense , Maja , Millefleurs , Mint , Musk , Narcissus , Orchid , Oriental , Patchouli , Pine forest , Potpourri , Rose , Rose red rose , Sandalwood , Sassafras , Spearmint , Spice , Spring rain , Valerian , Vanilla , Windsor soap , Wisteria , Woody , Ylang ylang |
| Flavoring purposes | Benzoin absolute replacer , Caraway seed , Valerian |
| Cosmetic purposes | Fragrance , Perfuming agents , Skin conditioning , Tonic |
Safety Information
Safety information
| European information : | |
| Most important hazard(s): | |
| Xn - Harmful. | |
| R 21/22 - Harmful in contact with skin and if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. R 42/43 - May cause sensitization by inhalation and skin contact. R 65 - Harmful: may cause lung damage if swallowed. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 | |
| GHS Label elements, including precautionary statements | |
| Pictogram |  |
| Signal word | Warning |
| Hazard statement(s) | |
| H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation | |
| Precautionary statement(s) | |
| P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P264 - Wash skin thouroughly after handling. P271 - Use only outdoors or in a well-ventilated area. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P302 + P352 - IF ON SKIN: wash with plenty of soap and water. P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention. P337 + P313 - IF eye irritation persists: Get medical advice/attention. P362 - Take off contaminated clothing and wash before reuse. P403 + P233 - Store in a well-ventilated place. Keep container tightly closed. P405 - Store locked up. P501 - Dispose of contents/ container to an approved waste disposal plant. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 2650 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 761, 1975. oral-rat LD50 1370 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 695, 1978. oral-rat LD50 2020 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 765, 1975. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 761, 1975. skin-rabbit LD50 1200 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 695, 1978. skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 765, 1975. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in use information
| Category: | |||
| cosmetic, flavor and fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| IFRA Critical Effect: | |||
| Sensitization | |||
| contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only) | |||
| farnesol | Max. Found: | ||
| eugenol | Max. Found: 85.30 % and Reason: Sensitization | ||
| isoeugenol | Max. Found: | ||
| methyl eugenol | Max. Found: | ||
| benzaldehyde | Max. Found: | ||
| benzyl alcohol | Max. Found: | ||
| Recommendation for clove leaf oil usage levels up to: | |||
| 8.0000 % in the fragrance concentrate. | |||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 30.00000 | |
| beverages(nonalcoholic): | - | 8.60000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | 14.00000 | 4.00000 | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 16.00000 | |
| fruit ices: | - | 16.00000 | |
| gelatins / puddings: | - | 5.00000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 22.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | 670.00000 | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety references
| European Food Safety Authority (EFSA) reference(s): |
| Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil View page or View pdf |
| Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy View page or View pdf |
| Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for clove oil in light of confirmatory data View page or View pdf |
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):8000-34-8 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| syzygium aromaticum l. leaf oil |
| Chemidplus:0008000348 |