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  1. 1.
    General Material Information
  2. 2.
    PhysChem Properties
  3. 3.
    Occurrences
  4. 4.
    Organoleptic Properties
  5. 5.
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  6. 6.
    Potential Uses
  7. 7.
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clove leaf oil

General Material Information

Preferred name clove leaf oil
Trivial Name Clove leaf oil Madagascar
Short Description essential oil steam-distilled from the leaves of the clove, eugenia caryophyllus, myrtaceae
CAS Number 8000-34-8
Deleted CAS Number 8015-97-2
FEMA Number 2325
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8015-97-2 ; CLOVE LEAF, OIL (EUGENIA SPP.)
Synonyms
  • caryophyllus aromaticus leaf oil
  • clove leaf EO crude
  • clove leaf EO rectified
  • clove leaf essential oil
  • clove leaf oil indonesia
  • clove leaf oil indonesian 70/80
  • clove leaf oil light
  • clove leaf oil madagascar
  • clove leaf oil madagascar 80/82
  • clove leaf oil madagascar bleached
  • clove leaf oil madagascar crude
  • clove leaf oil madagascar FCC
  • clove leaf oil min. 80/82/85 pct water white
  • clove leaf oil natural
  • clove leaf oil organic
  • clove leaf oil organic + NOP
  • clove leaf oil rectified
  • clove leaf oil rectified 74%
  • clove leaf oil redistilled
  • clove leaf oil redistilled FCC
  • clove leaf oil, bleached & filtered FCC, natural
  • clove leaf oil, indonesian
  • clove leaf oil, madagascar
  • clove leaf oil, madagascar, light
  • clove leaf oil, rectified
  • clove leaf oil, redistilled FCC
  • clove leaf oil, tech., natural
  • clove leave oil select 02 (Charabot)
  • clove leaves crude EO
  • clove leaves rectified ess. oil (for fragrance) (Robertet)
  • cloveleaf oil
  • cloveleaf oil, redistilled
  • cloves leaves deco EO
  • essential oil steam-distilled from the leaves of the clove, eugenia caryophyllus, myrtaceae
  • eugenia aromatica leaf oil
  • eugenia caroyphyllus leaf oil
  • eugenia caryophyllata leaf oil
  • eugenia caryophyllus leaf oil
  • jambosa caryophyllus leaf oil
  • love leaf oil rectified 85%
  • myrtus caryophyllus leaf oil
  • oil clove leaf redistilled indonesian 85/87% FCC
  • oil clove leaf redistilled indonesian 90/92%
  • syzygium aromaticum leaf oil
  • syzygium aromaticum l. leaf oil
  • Clove oil
  • Oils, clove
  • Essential oils, clove
  • Oil of Clove
  • Oils, clove leaf
  • Clove stem oil
  • Oils, clove stem
  • Oils, essential, clove
  • Clove oils
  • Clove bud oil
  • Oils, clove bud
  • Syzygium aromaticum bud oil
  • Eugenia caryophyllata bud oil
  • Oils, clove inflorescence
  • Essential clove oil
  • Syzygium aromaticum oil
  • Oils, essential, clove stem
  • Clove stem oils
  • Syzygium aromaticum stem oil
  • Eugenia caryophyllata stem oil
  • Essential oils, clove stem
  • Oils, essential, clove leaf
  • Clove leaf oils
  • Oils, clove leaves
  • Essential oils, clove leaf
  • Clove flower bud oil
  • Biox CD
  • Matran EC
  • Fresh Pack
  • Caryophyllus aromaticus oil
  • Oleum Caryophylli
  • Clove oil (Syzygium aromaticum)
  • HCF 114
  • Clove essential oil

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.5045
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

Suppliers

Anhui Haibei Aromatic and Allied Chemicals
Artiste Astral Extracts
Augustus Oils Berjé
Blue Pacific Flavors Bontoux
Bristol Botanicals Camden-Grey Essential Oils
Charabot Charkit Chemical
Citrus and Allied Essences De Monchy Aromatics
Diffusions Aromatiques ECSA Chemicals
Elixens America Ernesto Ventós
Excellentia International F. P. Aromatics Singapore
Fleurchem Gem Aromatics
George Uhe Company Global Essence
Golden Spice Haldin International
Indenta Group Indukern F&F
Jiangyin Healthway John Kellys (London)
K.L. Koh Enterprise Kalsec
Kanta Enterprises Lionel Hitchen
Lluch Essence M&U International
Mane Mentha & Allied Products
Moellhausen Natura Aromatik
Naturex Noble Molecular Research
OQEMA Payand Betrand
Penta International PerfumersWorld
Phoenix Aromas & Essential Oils Plant Lipids
Prinova PT Mitra Ayu Adi Pratama
PT. Nabateans Aromatic Quimdis
R C Treatt & Co Ltd Reincke & Fichtner
Robertet Silver Fern Chemical
SRS Aromatics Synthite Industries
The John D. Walsh Company The Lebermuth Company
The Lermond Company Ultra International
Ungerer & Company Van Aroma
Vigon International Zanos
Augustus Oils Ltd Berje Inc.
Bontoux SAS Charkit Chemical Corporation
Elixens America, Inc. Fleurchem, Inc.
Global Essence Inc. Indukern, S.A. F&F Ingredients Division
Jiangyin Healthway International Trade Co., Ltd Lluch Essence S.L.
M&U International LLC Moellhausen S.P.A.
Penta International Corporation PerfumersWorld Ltd.
Robertet, Inc. SRS Aromatics Ltd
The John D. Walsh Company, Inc R C Treatt and Co Ltd
Ultra International Limited Ernesto Ventós S.A.
Zanos Ltd.

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 8.621 to 8.704
Refractive Index 1.53 to 1.538 @ 20 °C
Optical Rotation -2
Flash Point TCC Value 93.33 °C TCC
Shelf life 24 months (or longer if stored properly.)
Storage notes Store in cool, dry place in tightly sealed containers, protected from heat and light.
Solubility
alcohol Yes
fixed oils Yes
isopropyl myristate Yes
paraffin oil, cloudy Yes
propylene glycol Yes
water, 754 mg/L @ 25 °C (est) Yes
water No
glycerin No

Organoleptic Properties

Odor Type: Spicy
spicy, aromatic, woody, balsamic, minty, peppery, phenolic, powdery
Odor strength medium
Substantivity 116 hour(s) at 100.00 %
Luebke, William tgsc, (1987) At 100.00 %. spicy aromatic woody balsamic minty peppery phenolic powdery
Flavor Type: Spicy
spicy, woody, aromatic, balsamic, minty, peppery, medicinal, waxy
Luebke, William tgsc, (1987) Spicy woody aromatic balsamic minty peppery medicinal waxy

Occurrences

Safety Information

Safety information

European information :
Most important hazard(s):
Xn - Harmful.
R 21/22 - Harmful in contact with skin and if swallowed.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
R 42/43 - May cause sensitization by inhalation and skin contact.
R 65 - Harmful: may cause lung damage if swallowed.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Skin irritation (Category 2), H315
Eye irritation (Category 2A), H319
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
GHS Label elements, including precautionary statements
Pictogramexclamation-mark.jpg
Signal word Warning
Hazard statement(s)
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary statement(s)
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 - Wash skin thouroughly after handling.
P271 - Use only outdoors or in a well-ventilated area.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P302 + P352 - IF ON SKIN: wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312 - Call a POISON CENTER or doctor/physician if you feel unwell.
P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention.
P337 + P313 - IF eye irritation persists: Get medical advice/attention.
P362 - Take off contaminated clothing and wash before reuse.
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
oral-rat LD50 2650 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 761, 1975.

oral-rat LD50 1370 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 695, 1978.

oral-rat LD50 2020 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 765, 1975.

Dermal Toxicity:
skin-rabbit LD50 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 761, 1975.

skin-rabbit LD50 1200 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 695, 1978.

skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 765, 1975.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Sensitization
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
farnesol Max. Found:
eugenol Max. Found: 85.30 % and Reason: Sensitization
isoeugenol Max. Found:
methyl eugenol Max. Found:
benzaldehyde Max. Found:
benzyl alcohol Max. Found:
Recommendation for clove leaf oil usage levels up to:
8.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -30.00000
beverages(nonalcoholic): -8.60000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: 14.000004.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -16.00000
fruit ices: -16.00000
gelatins / puddings: -5.00000
granulated sugar: --
gravies: --
hard candy: -22.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -670.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Authority (EFSA) reference(s):

Conclusion on the peer review of the pesticide risk assessment of the active substance plant oils/clove oil
View page or View pdf

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for clove oil in light of confirmatory data
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):8000-34-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
syzygium aromaticum l. leaf oil
Chemidplus:0008000348