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patchouli oil

General Material Information

Preferred name patchouli oil
Trivial Name Oils, patchouli
Short Description volatile oil obtained from the leaves of the patchouli, pogostemon cablin, labiatae
CAS Number 8014-09-3
FEMA Number 2838
FDA UNII Search
MDL MFCD00147854
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8014-09-3 ; PATCHOULY, OIL (POGOSTEMON SPP.)
Synonyms
  • patchouli crude essential oil
  • patchouli ess nat 01
  • patchouli ess. oil (for fragrance) (Robertet)
  • patchouli essential oil crude
  • patchouli fraction oil
  • patchouli heart
  • patchouli heart indonesia (Robertet)
  • patchouli heart n.3 (IFF)
  • patchouli indo EO
  • patchouli oil amber
  • patchouli oil dark
  • patchouli oil indonesia
  • patchouli oil indonesia / papua new guinea organic
  • patchouli oil indonesia iron free
  • patchouli oil indonesian
  • patchouli oil organic
  • patchouli oil redist
  • patchouli oil, dark
  • patchouli purecoeur essential oil
  • patchouly EO
  • pogostemon cablin oil
  • pogostemon patchouli oil
  • tilam wangi oil
  • volatile oil obtained from the leaves of the patchouli, pogostemon cablin, labiatae
  • Oils, patchouli
  • Oil of Patchouli

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Literature & References

pogostemon cablin oil
Canada Domestic Sub. List:8014-09-3
Pubchem (sid):135316842
Publications by PubMed
A pharmacokinetic study of patchouli alcohol after a single oral administration of patchouli alcohol or patchouli oil in rats.
Synergistic effect of fragrant herbs in Japanese scent sachets.
Progressive regulation of sesquiterpene biosynthesis in Arabidopsis and Patchouli (Pogostemon cablin) by the miR156-targeted SPL transcription factors.
A multiresidue method for simultaneous determination of 44 organophosphorous pesticides in Pogostemon cablin and related products using modified QuEChERS sample preparation procedure and GC-FPD.
In vitro and in vivo antibacterial activity of Pogostone.
Progressive Regulation of Sesquiterpene Biosynthesis in Arabidopsis and Patchouli (Pogostemon cablin) by the miR156-Targeted SPL Transcription Factors.
Prevention of UV radiation-induced cutaneous photoaging in mice by topical administration of patchouli oil.
Characterisation of the metabolism of pogostone in vitro and in vivo using liquid chromatography with mass spectrometry.
Expression, purification and activity assay of a patchoulol synthase cDNA variant fused to thioredoxin in Escherichia coli.
Evaluation of the antibacterial activity of patchouli oil.
Antimicrobial and Herbal Drug Resistance in Enteric Bacteria Isolated from Faecal Droppings of Common House Lizard/Gecko (Hemidactylus frenatus).
Development and structure of internal glands and external glandular trichomes in Pogostemon cablin.
Screening of some essential oils against Trichosporon species.
Insecticidal activity of pogostone against Spodoptera litura and Spodoptera exigua (Lepidoptera: Noctuidae).
Antifungal effect of Allium tuberosum, Cinnamomum cassia, and Pogostemon cablin essential oils and their components against population of Aspergillus species.
Insecticidal and repellence activity of the essential oil of Pogostemon cablin against urban ants species.
Study on the grafting of chitosan-gelatin microcapsules onto cotton fabrics and its antibacterial effect.
Patchouli alcohol, an essential oil of Pogostemon cablin, exhibits anti-tumorigenic activity in human colorectal cancer cells.
Virtual screening of compounds from the patchouli oil of Pogostemon herba for COX-1 inhibition.
[Extraction and analysis of the essential oil in Pogostemon cablin by enzymatic hydrolysis and inhibitory activity against Hela cell proliferation].
Quantitative and physical evaluation of patchouli essential oils obtained from different sources of Pogostemon cablin.
Secondary metabolites and antioxidant capacities of Waldheimia glabra (Decne.) Regel from Nepal.
Technology for efficient and successful delivery of vermicompost colonized bioinoculants in Pogostemon cablin (patchouli) Benth.
Selective separation of patchouli alcohol from the essential oil of Cablin potchouli by inclusion crystalline method.
Acaricidal activity of DHEMH, derived from patchouli oil, against house dust mite, Dermatophagoides farinae.
Chemical constituents, antioxidant and antimocrobial activity of essential oil of Pogostemon paniculatus (Willd.).
Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo.
Volatile oil composition of Pogostemon heyneanus and comparison of its composition with patchouli oil.
[Identification method with significant specificity of volatile oil of Pogostemon cablin].
Evaluation of the toxicity of 17 essential oils against Choristoneura rosaceana (Lepidoptera: Tortricidae) and Trichoplusia ni (Lepidoptera: Noctuidae).
Novel silicon-based patchouli odorants of the trialkyl(1-hydroxy-1-methylethyl)silane type: design, synthesis, and olfactory properties.
[Protective effect of Pogostemon cablin on membrane fluidity of intestinal epithelia cell in ischemia/ reperfusion rats after ischemia/reperfusion].
[Effect of atractylodes rhizome oil and other volatile oils on percutaneous absorption of baicalin].
Insecticidal properties of several essential oils on the house fly (Musca domestica L.).
Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin.
The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases.
GC-MS fingerprint of Pogostemon cablin in China.
Comparative repellency of 38 essential oils against mosquito bites.
Determination of patchoulic alcohol in Herba Pogostemonis by GC-MS-MS.
[Investigation on the influential factors of the volatile oil and main constituent content in Pogostemon cablin].
[Study on purification technology of patchouly oil with molecular distillation].
[Pharmacokinetics of patchouli alcohol and patchouli alcohol in patchouli oil after iv administrated to rats].
Application of comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry in the analysis of volatile oil of traditional Chinese medicines.
Toxicity and repellency of patchouli oil and patchouli alcohol against Formosan subterranean termites Coptotermes formosanus Shiraki (Isoptera: Rhinotermitidae).
[Anti-Candida albicans activity of essential oils including Lemongrass (Cymbopogon citratus) oil and its component, citral].
[Two chemotypes of Pogostemon cablin and influence of region of cultivation and harvesting time on volatile oil composition].
[Constituents analysis on volatile oil of Pogostemon cablin from different collection time cultivated in Hainan].
[DNA profiling of Pogostemon cablin chemotypes differing in essential oil composition].
[GC-MS analysis of volatile oil of Herba Pogostemonis collected from Leizhou county].
[GC-MS analysis of volatile oil of herba Pogostemonis collected from Gaoyao county].
Effects of fragrance inhalation on sympathetic activity in normal adults.
Production of patchouli mild mosaic virus resistant patchouli plants by genetic engineering of coat protein precursor gene.
Regeneration of patchouli (Pogostemon cablin Benth.) plants from leaf and node callus, and evaluation after growth in the field.
Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.5029
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:Patchouli

Suppliers

Absolute Cosmetic Essentials Aditi Essentials
Albert Vieille SAS Ambles Nature et Chimie
Anhui Haibei Aromatic and Allied Chemicals
Arora Aromatics Artiste
Associate Allied Chemicals Astral Extracts
Augustus Oils Azelis UK
Berjé Blue Pacific Flavors
Bontoux Bristol Botanicals
Camden-Grey Essential Oils Charabot
Citrus and Allied Essences Creatingperfume.com
De Monchy Aromatics Dongguan Meiherb Biotech
ECSA Chemicals Elixens America
Ernesto Ventós Excellentia International
F. P. Aromatics Singapore Fine Fragrances Pvt Ltd
Fleurchem Frey + Lau
Fuzhou Farwell Gem Aromatics
George Uhe Company Global Essence
Haldin International HDDES Group
Hermitage Oils IFF
Indenta Group India Essential Oils
Indukern F&F Isobionics
Jiangyin Healthway John Kellys (London)
K.L. Koh Enterprise Kanta Enterprises
Lluch Essence M&U International
Mane Mentha & Allied Products
Moellhausen Natura Aromatik
Natural & Essential Oils Noble Molecular Research
OQEMA Payand Betrand
Penta International PerfumersWorld
Phoenix Aromas & Essential Oils Plants Power
Prinova Prodasynth
PT Mitra Ayu Adi Pratama PT. Nabateans Aromatic
Quimdis R C Treatt & Co Ltd
Reincke & Fichtner Robertet
Sigma-Aldrich Silverline Chemicals
SRS Aromatics Sunaux International
Synthite Industries Taytonn ASCC
The Good Scents Company The John D. Walsh Company
The Lebermuth Company The Lermond Company
The Perfumers Apprentice The Perfumery
Ultra International Ungerer & Company
Van Aroma Vigon International
Zanos Augustus Oils Ltd
Azelis UK Ltd. Berje Inc.
Bontoux SAS Elixens America, Inc.
Fleurchem, Inc. Global Essence Inc.
Hermitage Oils / Neroli S.R.L. Indukern, S.A. F&F Ingredients Division
Jiangyin Healthway International Trade Co., Ltd Lluch Essence S.L.
M&U International LLC Moellhausen S.P.A.
Penta International Corporation PerfumersWorld Ltd.
Robertet, Inc. SRS Aromatics Ltd
Taytonn ASCC Pte Ltd The John D. Walsh Company, Inc
R C Treatt and Co Ltd Ultra International Limited
Ernesto Ventós S.A. Zanos Ltd.

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 7.905 to 8.113
Specific gravity @ 20 °C
Pounds per Gallon 7.939 to 8.147
Refractive Index 1.507 to 1.515 @ 20 °C
Optical Rotation -48 to -65
Flash Point TCC Value 87.78 °C TCC
Shelf life 36 months (or longer if stored properly.)
Storage notes Store in cool, dry place in tightly sealed containers, protected from heat and light.
Solubility
alcohol Yes
fixed oils Yes
paraffin oil Yes
water, 42.87 mg/L @ 25 °C (est) Yes
water No
glycerin No
Stability
bath foam Unspecified
cream Unspecified
hair spray Unspecified
lipstick Unspecified
powder Unspecified
shampoo Unspecified
soap Unspecified

Organoleptic Properties

Odor Type: Woody
woody, woody old wood, dry, earthy, weedy, balsamic, spicy, minty
Odor strength medium
Substantivity 400 hour(s) at 100.00 %
Luebke, William tgsc, (2017) At 100.00 %. woody old wood dry earthy weedy balsamic spicy minty
Flavor Type: Woody
woody, earthy, weedy, balsamic, spicy, camphoreous
Luebke, William tgsc, (2017) Woody earthy weedy balsamic spicy camphoreous
General comment Woody earthy weedy balsamic spicy camphoreous

Occurrences

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Aspiration hazard (Category 1), H304
Skin corrosion/irritation (Category 3), H316
Chronic aquatic toxicity (Category 2), H411
GHS Label elements, including precautionary statements
Pictogramhealth-hazard.jpgexclamation-mark.jpgenvironment.jpg
Signal word Warning
Hazard statement(s)
H304 - May be fatal if swallowed and enters airways
H316 - Causes mild skin irritation
H411 - Toxic to aquatic life with long lasting effects
Precautionary statement(s)
P273 - Avoid release to the environment.
P331 - Do NOT induce vomiting.
P391 - Collect spillage. Hazardous to the aquatic environment
P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
oral-rat LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 791, 1982.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 791, 1982.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for patchouli oil usage levels up to:
10.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -10.00000
beverages(nonalcoholic): -0.88000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: 43.00000220.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.10000
fruit ices: -1.10000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -6.30000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
EPA Substance Registry Services (TSCA):8014-09-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
pogostemon cablin oil
Chemidplus:0008014093
RTECS:RW7126400 for cas# 8014-09-3