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hop oil CO2 extract

Hop oil CO2 extract is a green-scented, spicy-flavored natural extract from Humulus lupulus used primarily in cosmetics and beer flavoring applications.

General Material Description

Hop oil CO2 extract is a botanical extract obtained from Humulus lupulus, commonly known as hops. This oil is recognized for its characteristic green odor and spicy flavor, which are typical sensory traits associated with hops. The extract is obtained through supercritical carbon dioxide extraction, a method that preserves many aromatic and flavor compounds. Known synonyms include CO2 hop extract, hops CO2 extract, and hops oil CO2 extract. The substance is listed in public chemical databases such as PubChem and has a CAS number 8007-04-3. Sourced mainly from hop cones, the extract captures essential volatile constituents responsible for the unique scent and taste of hops, making it valuable in flavor and fragrance industries.

Occurrence, Applicability & Potential Uses

Hop oil CO2 extract occurs naturally in the hop plant (Humulus lupulus), where it contributes to the plant's aroma and flavor profile. Its primary applications include use as a flavoring agent, most notably in beer production where it imparts the distinctive spicy and herbal notes characteristic of hop-flavored brews. Additionally, the extract serves as an ingredient in cosmetic formulations, such as perfuming agents and tonics, valued for its aromatic qualities. The material's safety and usage standards are guided by regulations like FEMA (US), which oversee flavoring substances in food and beverages to ensure appropriate application levels and consumer protection.

Physico-Chemical Properties Summary

Hop oil CO2 extract demonstrates solubility characteristics that influence its application in formulations. It is soluble in alcohol and has minimal solubility in water, approximately 0.01396 mg/L at 25 °C (estimated), which facilitates its use in alcoholic beverages like beer. The relatively low water solubility restricts its direct integration into aqueous systems without solubilizing agents. These physicochemical traits support its incorporation into fragrance and flavor blends where alcohol is a common solvent. The extract's green odor and spicy flavor profile stem from its complex mixture of volatile compounds preserved by the CO2 extraction method, contributing to its stability and performance in both cosmetic and food uses.

FAQ

What is hop oil CO2 extract and how is it obtained?
Hop oil CO2 extract is a natural essential oil derived from the cones of the hop plant, Humulus lupulus. The extraction is performed using supercritical carbon dioxide, a method that efficiently isolates aromatic compounds without the use of high heat or solvents. This technique preserves the green odor and spicy flavor typical of hops. It is also known as CO2 hop extract or hops CO2 extract and carries the CAS number 8007-04-3.
Where is hop oil CO2 extract commonly used and what are its sensory properties?
This extract is mainly utilized as a flavoring agent in beer, imparting characteristic spicy and herbal notes that define hop-flavored beverages. In addition, it finds applications in the cosmetic industry as a fragrance and perfuming agent, including tonic formulations. Its sensory profile features a green odor and spicy flavor, attributes that result from its rich composition of volatile compounds retained through the CO2 extraction process.
What safety standards and regulations apply to hop oil CO2 extract?
Hop oil CO2 extract is subject to safety assessments and regulatory oversight by bodies such as FEMA (US) for flavoring in foods and beverages. The extract does not possess significant hazard classifications under OSHA HCS standards and has been reviewed for use in cosmetics and flavorings without notable restrictions. Toxicological data from animal studies report relatively high oral LD50 values, indicating low acute toxicity. Regulatory resources include RIFM fragrance safety assessments and IFRA guidelines, which help ensure safe levels in consumer products.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

humulus lupulus oil CO2 extract
Canada Domestic Sub. List:8007-04-3
Pubchem (sid):135306977
Publications by PubMed
Quantitative trait loci in hop (Humulus lupulus L.) reveal complex genetic architecture underlying variation in sex, yield and cone chemistry.
Effect of linalool as a component of Humulus lupulus on doxorubicin-induced antitumor activity.
Headspace solid-phase microextraction combined with mass spectrometry as a powerful analytical tool for profiling the terpenoid metabolomic pattern of hop-essential oil derived from Saaz variety.
A dietary supplement to improve the quality of sleep: a randomized placebo controlled trial.
Heterodimeric geranyl(geranyl)diphosphate synthase from hop (Humulus lupulus) and the evolution of monoterpene biosynthesis.
Effects of powdery mildew fungicide programs on twospotted spider mite (Acari: Tetranychidae), hop aphid (Hemiptera: Aphididae), and their natural enemies in hop yards.
Comparison of odor-active compounds in the spicy fraction of hop (Humulus lupulus L.) essential oil from four different varieties.
A TLC bioautographic assay for the detection of nitrofurantoin resistance reversal compound.
The combination of gas chromatography-olfactometry and multidimensional gas chromatography for the characterisation of essential oils.
Sedating effects of Humulus lupulus L. extracts.
Effects of beer and hop on ionotropic gamma-aminobutyric acid receptors.
Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.).
Characterization of varietal differences in essential oil components of hops (Humulus lupulus) by SFC-FTIR spectroscopy.
Direct thermal desorption-gas chromatography and gas chromatography-mass spectrometry profiling of hop (Humulus lupulus L.) essential oils in support of varietal characterization.
Fractionation by SFE and microcolumn analysis of the essential oil and the bitter principles of hops.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:1302.13.0000
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

General Material Information

Preferred name hop oil CO2 extract
Trivial Name humulus lupulus oil CO2 extract
CAS Number 8007-04-3
FDA UNII Search
FDA Mainterm 8007-04-3 ; HOPS, OIL (HUMULUS LUPULUS L.)
Synonyms
  • CO2 hop extract
  • hops CO2 extract
  • hops oil CO2 extract
  • humulus lupulus oil CO2 extract

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water, 0.01396 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Green
sharp, green, spicy, sweet, beer, herbal
Flavor Type: Spicy
hops
General comment Hops

Occurrences

Potential Uses

Applications
Flavoring purposes Beer
Cosmetic purposes Fragrance , Perfuming agents , Tonic

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 3500 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

oral-rat LD50 2700 mg/kg
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Safety references

European Food Safety Authority (EFSA) reference(s):

Safety and efficacy of a super critical carbon dioxide extract of Humulus lupulus L. flos when used as a feed flavouring for all animal species
View page or View pdf

EPI System: View
EPA Substance Registry Services (TSCA):8007-04-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
humulus lupulus oil CO2 extract
Chemidplus:0008007043