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clausena anisata leaf oil

Clausena anisata leaf oil is a plant-derived essential oil known for its licorice-like odor and chemical properties, primarily used for research rather than in flavor or fragrance products.

General Material Description

Clausena anisata leaf oil is an essential oil extracted from the leaves of the Clausena anisata plant, also known under synonyms including clausena inaequalis var. abyssinica leaf oil and clausena anisata hook. f. leaf oil. This plant-based oil exhibits a characteristic licorice scent, often described as resembling anisic star anise at full concentration. The oil is a complex chemical mixture whose components provide this distinctive odor profile. Clausena anisata leaf oil is hydrophobic and soluble in alcohols but insoluble in water, reflecting properties typical of many essential oils. Its notable CAS number is 91771-51-6, and it is listed in authoritative chemical databases such as PubChem. The oil is primarily of interest for informational and research purposes rather than commercial fragrance or flavor use.

Occurrence, Applicability & Potential Uses

Clausena anisata leaf oil occurs naturally in the leaves of the Clausena anisata plant, a species native to certain regions where it grows as a shrub or small tree. The oil is traditionally extracted through methods such as steam distillation from the botanical material. While it possesses a licorice-like aroma, current usage recommendations specify that this oil is informational only and is not used in fragrance or flavor applications. This aligns with regulatory and safety perspectives including the IFRA (Global) guidelines, which provide standards for essential oils used in consumer products. Its primary relevance lies in chemical and botanical research domains rather than commercial formulation.

Physico-Chemical Properties Summary

The oil demonstrates selective solubility, dissolving readily in alcohol solvents while showing no solubility in water, indicative of its hydrophobic character and essential oil classification. This property influences its handling and formulation possibilities, as it is compatible with alcoholic bases but unsuitable for aqueous solutions without emulsification. Its molecular constituents confer the distinctive licorice scent, which may guide its application constraints. There is limited toxicological data available, and no significant hazard classifications exist under OSHA regulations, underscoring the oil's current status as a substance primarily for research, with no established use in consumer fragrance or flavor products. Stability and volatility typical of leaf-derived essential oils also inform its physicochemical profile.

FAQ

What is Clausena anisata leaf oil and where does it come from?
Clausena anisata leaf oil is a natural essential oil obtained from the leaves of the Clausena anisata plant species. It is also known by various synonyms, including clausena inaequalis var. abyssinica leaf oil. The oil carries a characteristic licorice-like odor, reminiscent of anisic star anise. Extracted primarily through steam distillation from the plant's leaves, this oil is valued mostly for informational and research purposes rather than commercial fragrance or flavoring.
How is Clausena anisata leaf oil typically used and what are its solubility properties?
This essential oil is chiefly used in scientific study rather than in consumer fragrances or flavor formulations. It dissolves well in alcohol but is insoluble in water, reflecting its hydrophobic nature. Due to its specialized applications and lack of significant safety data, the oil is not commonly incorporated into commercial product formulations. Its licorice aroma is a distinctive sensory attribute, but usage guidelines currently restrict its application outside of research contexts.
What regulatory or safety information is associated with Clausena anisata leaf oil?
Regulatory evaluations, including those under the IFRA (Global) standards, indicate that Clausena anisata leaf oil is not recommended for fragrance or flavor use. Safety data available from sources such as OSHA hazard classifications report no identified hazards, and toxicological data remain limited. Usage recommendations typically designate the oil as informational only. Links to resources such as the EPA's ACToR database and the National Institute of Allergy and Infectious Diseases provide additional chemical data for reference.

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Literature & References

clausena anisata hook. f. leaf oil
Pubchem (sid):135315287
Publications by PubMed
Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells.
Ethnoveterinary medicinal plants used by the Maale and Ari ethnic communities in southern Ethiopia.
Isolation of seselin from Clausena anisata (Rutaceae) leaves and its effects on the feeding and development of Lucilia cuprina larvae may explain its use in ethnoveterinary medicine.
Efficacy and toxicity of thirteen plant leaf acetone extracts used in ethnoveterinary medicine in South Africa on egg hatching and larval development of Haemonchus contortus.
Chemical constituents from stem bark and roots of Clausena anisata.
Some southern African plant species used to treat helminth infections in ethnoveterinary medicine have excellent antifungal activities.
Assessment of long-term storage on antimicrobial and cyclooxygenase-inhibitory properties of South African medicinal plants.
Extracts of four plant species used traditionally to treat myiasis influence pupation rate, pupal mass and adult blowfly emergence of Lucilia cuprina and Chrysomya marginalis (Diptera: Calliphoridae).
Evaluation of plant species used traditionally to treat myiasis for activity on the survival and development of Lucilia cuprina and Chrysomya marginalis (Diptera: Calliphoridae).
Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants.
Antiplasmodial and analgesic activities of Clausena anisata.
Isolation and identification of antibacterial compound from the leaves of Cassia auriculata.
Evaluation of Clausena anisata essential oil from Cameroon for controlling food spoilage fungi and its potential use as an antiradical agent.
Ethnobotanical study of anthelmintic and other medicinal plants traditionally used in Loitoktok district of Kenya.
Profile of heavy metals in some medicinal plants from Ghana commonly used as components of herbal formulations.
Gamma-lactone carbazoles from Clausena anisata.
Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia.
Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections.
Plants used to treat epilepsy by Tanzanian traditional healers.
Comparative in vitro effects of AZT and extracts of Ocimum gratissimum, Ficus polita, Clausena anisata, Alchornea cordifolia, and Elaeophorbia drupifera against HIV-1 and HIV-2 infections.
Hypoglycaemic effect of Clausena anisata (Willd) Hook methanolic root extract in rats.
New carbazole alkaloids from Clausena anisata with antitumor promoting activity.
Screening of Zulu medicinal plants for angiotensin converting enzyme (ACE) inhibitors.
Clausenol and clausenine--two carbazole alkaloids from Clausena anisata.
New biogenetically-significant constituents of Clausena anisata and Murraya koenigii.
Estragole: an acute toxic principle from the volatile oil of the leaves of Clausena anisata.
Constituents of the Essential Oil of Clausena anisata Leaves.
The mutagenicities of seven coumarin derivatives and a furan derivative (nimbolide) isolated from three medicinal plants.
Structure-activity relationship in the toxicity of some naturally occurring coumarins-chalepin, imperatorin and oxypeucedanine.
[Constituents of Clausena anisata (Willd.) Oliv. (Rutaceae). I. Coumarins from the root bark (author's transl)].

Other Information

Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:Clausena anisata

General Material Information

Trivial Name clausena anisata leaf oil
Short Description clausena inaequalis var. abyssinica leaf oil
CAS Number 91771-51-6
ECHA Number 294-943-7
FDA UNII Search
Synonyms
  • clausena inaequalis var. abyssinica leaf oil
  • clausena anisata hook. f. leaf oil
  • Clausena anisata, ext.

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water No

Organoleptic Properties

Odor Type: Licorice
anisic, anise
General comment At 100.00 %. anisic star anise

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
information only not used for fragrances or flavors
Recommendation for clausena anisata leaf oil usage levels up to:
not for fragrance use.
Recommendation for clausena anisata leaf oil flavor usage levels up to:
not for flavor use.

Safety references

EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
clausena anisata hook. f. leaf oil
Chemidplus:0091771516