Preferred name | grapefruit oil c.p. israel |
Trivial Name | Oils, grapefruit |
Short Description | citrus paradisi peel oil israel |
CAS Number | 8016-20-4 |
FEMA Number | 2530 |
FDA UNII | Search |
FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
FDA Mainterm | 8016-20-4 ; GRAPEFRUIT, OIL (CITRUS PARADISI MACF.) |
Synonyms |
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Perfumer & Flavorists | Start search |
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NCBI | Start search |
FDA Substances Added to Food (formerly EAFUS): | View |
Export Tariff Code: | 3301.19.0000 |
Wikipedia: | View |
FAO: | BASIC PRINCIPLES OF STEAM DISTILLATION |
Citrus and Allied Essences | Fleurchem |
George Uhe Company | Hermitage Oils |
Kanta Enterprises | Lluch Essence |
PCW France | Fleurchem, Inc. |
Hermitage Oils / Neroli S.R.L. | Lluch Essence S.L. |
Material listed in food chemical codex | No |
Specific gravity | @ 25 °C |
Pounds per Gallon | 7.056 to 7.123 |
Refractive Index | 1.475 to 1.478 @ 20 °C |
Flash Point TCC Value | 43.89 °C TCC |
Solubility | |
alcohol | Yes |
water, 4.581 mg/L @ 25 °C (est) | Yes |
water | No |
Odor Type: Citrus | |
citrus, grapefruit, grapefruit peel | |
General comment | At 100.00 %. citrus grapefruit peel |
Flavor Type: Citrus | |
grapefruit, grapefruit peel | |
General comment | Grapefruit |
(data available) |
European information : | |
Most important hazard(s): | |
Xi - Irritant | |
R 10 - Flammable. R 38 - Irritating to skin. R 43 - May cause sensitisation by skin contact. R 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R 65 - Harmful: may cause lung damage if swallowed. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet. S 62 - If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label. | |
Hazards identification | |
Classification of the substance or mixture | |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
Flammable liquids (Category 3), H226 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 | |
GHS Label elements, including precautionary statements | |
Pictogram | ![]() ![]() |
Signal word | Warning |
Hazard statement(s) | |
H226 - Flammable liquid and vapour H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation | |
Precautionary statement(s) | |
P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233 - Keep container tightly closed. P240 - Ground/bond container and receiving equipment. P241 - Use explosion-proof electrical/ventilating/lighting/…/equipment. P242 - Use only non-sparking tools. P243 - Take precautionary measures against static discharge. P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P264 - Wash skin thouroughly after handling. P271 - Use only outdoors or in a well-ventilated area. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P321 - Specific treatment (see supplemental first aid instructions on this label). P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention. P337 + P313 - IF eye irritation persists: Get medical advice/attention. P362 - Take off contaminated clothing and wash before reuse. P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction. P403 + P233 - Store in a well-ventilated place. Keep container tightly closed. P403 + P235 - Store in a well-ventilated place. Keep cool. P405 - Store locked up. P501 - Dispose of contents/ container to an approved waste disposal plant. | |
Oral/Parenteral Toxicity: | |
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 723, 1974. | |
Dermal Toxicity: | |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 12, Pg. 723, 1974. | |
Inhalation Toxicity: | |
Not determined |
Category: | |||
flavor and fragrance agents | |||
RIFM Fragrance Material Safety Assessment: Search | |||
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
IFRA Critical Effect: | |||
Phototoxicity | |||
IFRA Purity Specification: | |||
IFRA fragrance material specification: | |||
Where the bergapten (5-methoxypsoralen) content of all relevant oils present in a compound has been determined, it is recommended that for applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, the total level of bergapten in the consumer products should not exceed 0.0015% (15 ppm). This is equivalent to 0.0075% (75 ppm) in a fragrance compound used at 20% in the consumer product. Where the level of bergapten has not been determined by appropriate methods, the limits specified in the guidelines on individual oils should apply. In those cases, where such oils are used in combination with other phototoxic ingredients, the additive effect has to be taken into consideration and the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic fragrance ingredients, expressed in % of their recommended maximum level in the consumer product, shall not exceed 100. | |||
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only) | |||
citronellol | Max. Found: | ||
geraniol | Max. Found: | ||
(E)-2-hexen-1-al | Max. Found: trace to | ||
farnesol | Max. Found: | ||
citral | Max. Found: 0.1 % and Reason: Sensitization | ||
citronellal | Max. Found: 0.1 % and Reason: Sensitization | ||
View the IFRA Standard | |||
View IFRA Standards Library for complete information. | |||
Please review Amendment 49 IFRA documentation for complete information. | |||
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): | |||
Category 1: Products applied to the lips | |||
4.0 % | |||
Category 2: Products applied to the axillae | |||
4.0 % | |||
Category 3: Products applied to the face/body using fingertips | |||
4.0 % | |||
Category 4: Products related to fine fragrance | |||
4.0 % | |||
Category 5: Products applied to the face and body using the hands (palms), primarily leave-on | |||
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on | |||
4.0 % | |||
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on | |||
4.0 % | |||
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on | |||
4.0 % | |||
Category 5D: Baby Creams, baby Oils and baby talc | |||
4.0 % | |||
Category 6: Products with oral and lip exposure | |||
4.0 % | |||
Category 7: Products applied to the hair with some hand contact | |||
Category 7A: Rinse-off products applied to the hair with some hand contact | |||
No Restriction % | |||
Category 7B: Leave-on products applied to the hair with some hand contact | |||
4.0 % | |||
Category 8: Products with significant anogenital exposure | |||
4.0 % | |||
Category 9: Products with body and hand exposure, primarily rinse off | |||
No Restriction % | |||
Category 10: Household care products with mostly hand contact | |||
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) | |||
No Restriction % | |||
Category 10B: Household aerosol/spray products | |||
4.0 % | |||
Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate | |||
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure | |||
No Restriction % | |||
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure | |||
4.0 % | |||
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin | |||
No Restriction | |||
Notes: | |||
IFRA FLAVOR REQUIREMENTS: | |||
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. | |||
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
publication number: 3 | |||
Click here to view publication 3 | |||
average usual ppm | average maximum ppm | ||
baked goods: | - | 370.00000 | |
beverages(nonalcoholic): | - | 160.00000 | |
beverages(alcoholic): | - | - | |
breakfast cereal: | - | - | |
cheese: | - | - | |
chewing gum: | - | 1500.00000 | |
condiments / relishes: | - | - | |
confectionery froastings: | - | - | |
egg products: | - | - | |
fats / oils: | - | - | |
fish products: | - | - | |
frozen dairy: | - | 180.00000 | |
fruit ices: | - | 180.00000 | |
gelatins / puddings: | - | 250.00000 | |
granulated sugar: | - | - | |
gravies: | - | - | |
hard candy: | - | 630.00000 | |
imitation dairy: | - | - | |
instant coffee / tea: | - | - | |
jams / jellies: | - | - | |
meat products: | - | - | |
milk products: | - | - | |
nut products: | - | - | |
other grains: | - | - | |
poultry: | - | - | |
processed fruits: | - | - | |
processed vegetables: | - | - | |
reconstituted vegetables: | - | - | |
seasonings / flavors: | - | - | |
snack foods: | - | - | |
soft candy: | - | - | |
soups: | - | - | |
sugar substitutes: | - | - | |
sweet sauces: | - | - |
EPI System: View |
ClinicalTrials.gov:search |
Daily Med:search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):8016-20-4 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:1 |
citrus paradisi macf. peel oil |
Chemidplus:0008016204 |
RTECS:RI7199000 for cas# 8016-20-4 |