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clary sage oil russia

General Material Information

Preferred name clary sage oil russia
Trivial Name clary sage oil Russia
Short Description salvia sclarea oil russia
CAS Number 8016-63-5
FEMA Number 2321
FDA UNII Search
COE Number 415
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8016-63-5 ; CLARY, OIL (SALVIA SCLAREA L.)
Synonyms
  • sage clary russia ess.oil (for fragrance) (Robertet)
  • sage clary russian EO
  • nutmeg sage oil russia
  • salvia asperata oil russia
  • salvia pamirica oil russia
  • salvia sclarea oil russia
  • salvia sclarea l. oil
  • Oils, clary sage
  • Clary sage oil
  • Oil of muscatel
  • Sage oil Clary
  • Oils, Salviasclarea
  • Clary sage absolute
  • Salvia sclarea oil

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

salvia sclarea l. oil
Canada Domestic Sub. List:8016-63-5
Pubchem (sid):135311392
Publications by PubMed
Modulation of mecA Gene Expression by Essential Oil from Salvia sclarea and Synergism with Oxacillin in Methicillin Resistant Staphylococcus epidermidis Carrying Different Types of Staphylococcal Chromosomal Cassette mec.
Antifungal Effect of Essential Oils against Fusarium Keratitis Isolates.
Application of Heavy Metal Rich Tannery Sludge on Sustainable Growth, Yield and Metal Accumulation by Clarysage (Salvia sclarea L.).
The inhibition the Tet(K) efflux pump of tetracycline resistant Staphylococcus epidermidis by essential oils from three Salvia species.
The effect of clary sage oil on staphylococci responsible for wound infections.
Evaluation of Repellency Effect of Essential Oils of Satureja khuzestanica (Carvacrol), Myrtus communis (Myrtle), Lavendula officinalis and Salvia sclarea using Standard WHO Repellency Tests.
Effects of Salvia sclarea on chronic immobilization stress induced endothelial dysfunction in rats.
Essential oil composition, antioxidant and antifungal activities of Salvia sclarea L. from Munzur Valley in Tunceli, Turkey.
Presence of monoterpene synthase in four Labiatae species and Solid-Phase Microextraction- Gas chromatography-Mass Spectroscopy analysis of their aroma profiles.
In Vitro Antibacterial and Antibiotic Resistance Modifying Effect of Bioactive Plant Extracts on Methicillin-Resistant Staphylococcus epidermidis.
Screening of some essential oils against Trichosporon species.
Chronic food administration of Salvia sclarea oil reduces animals' anxious and dominant behavior.
Randomized controlled trial for Salvia sclarea or Lavandula angustifolia: differential effects on blood pressure in female patients with urinary incontinence undergoing urodynamic examination.
Extracellular localization of the diterpene sclareol in clary sage (Salvia sclarea L., Lamiaceae).
Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.
Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.
Effect of γ-irradiation on bioactivity, fatty acid compositions and volatile compounds of clary sage seed (Salvia sclarea L.).
Morphological characterisation and agronomical parameters of different species of Salvia sp. (Lamiaceae).
Essential oil content and composition, nutrient and mycorrhizal status of some aromatic and medicinal plants of northern Greece.
Antidepressant-like effect of Salvia sclarea is explained by modulation of dopamine activities in rats.
Intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.
Chemical composition and biological activities of essential oil from Salvia sclarea plants regenerated in vitro.
Diversity of essential oil glands of clary sage (Salvia sclarea L., Lamiaceae).
Effect of aromatherapy on symptoms of dysmenorrhea in college students: A randomized placebo-controlled clinical trial.
[Analysis of essential oil components by GC/FTIR and GC/MS].
Composition and antifungal activity on soil-borne pathogens of the essential oil of Salvia sclarea from Greece.
Chromatographic (GC-MS, HPLC) and virological evaluations of Salvia sclarea infected by BBWV-I.
Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea.
Studies on the genotoxic properties of essential oils with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay.
[Quality control of essential oil of muscat sage (Salvia sclarea) during laboratory and industrial preparation. IV. Causes of color changes].
[Effect of Salvia sclarea essential oil on indices of the hematopoietic, immune and enzyme systems].
Experimental studies on certain effects of the essential oil of Salvia sclarea L. on the central nervous system.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 20 °C
Pounds per Gallon 7.381 to 7.739
Refractive Index 1.458 to 1.473 @ 20 °C
Flash Point TCC Value 56.67 °C TCC
Solubility
alcohol Yes
water, 20.12 mg/L @ 25 °C (est) Yes
water No
Stability
alkali Unspecified

Organoleptic Properties

Odor Type: Herbal
fresh, herbal, tea green tea, woody, weedy, dry, spicy, sage, powdery
Odor strength medium
Substantivity 36 hour(s) at 100.00 %
Luebke, William tgsc, (2017) At 100.00 %. fresh herbal green tea woody weedy dry spicy sage powdery
Flavor Type: Herbal
herbal, spicy, green, tea, hay, sage, powdery, woody
Luebke, William tgsc, (2017) Herbal spicy green tea hay sage powdery woody

Occurrences

Potential Uses

Applications
Odor purposes Acacia, Agrumen aldehyde, Aldehydic, Alpine bouquet, Amber, Ambergris, Angelica, Balsam, Bergamot, Boxwood berry, Cabreuva wood, Calamus oil replacer, Carnation, Champaca, Chrysanthemum, Chypre, Cigar, Cistus, Citrus, Clary sage oil replacer, Clematis, Clean linen, Clover, Cologne, Copaiba balsam, Coriander, Coronilla, Country meadow, Crabapple blossom, Cranberry, Croton eluteria bark, Cucumber, Currant bud absolute replacer, Daffodil, Daphne, Deertongue absolute replacer, Dogwood, Earth, Elder flower, Evergreen, Fern, Fir needle oil replacer, Flouve, Flouve blossom, Foliage, Frankincense, Freesia, Fungus, Galangal root, Genet, Ginger white ginger, Grapefruit, Habuba, Hancornia, Hay new mown hay, Heather, Herbal, Immortelle, Incense, Ivy, Jasmin, Jonquil, Lavender, Leather, Mimosa, Musk, Neroli, Ocean sea, Orange bitter orange peel, Orchid, Oriental, Palmarosa oil replacer, Passion blossom, Petitgrain, Pine forest, Poppy red poppy, Powder, Privet, Privet blossom, Rhubarb, Rose tea rose, Rose white rose, Sandalwood, Spikenard oil replacer, Spring rain, Sweet grass, Tea green tea, Tobacco, Tulip, Wisteria, Witch hazel, Woodruff, Woody, Yerba mate
Flavoring purposes Angelica, Cistus, Copaiba balsam, Coriander, Croton eluteria bark, Currant bud absolute replacer, Galangal root, Immortelle, Orange bitter orange peel, Pear prickly pear, Tea black tea, Tea herbal tea, Yerba mate
Other purposes Amour-amour, Cabochard, Shalimar, Tabu, Timber, Vine, Vol de nuit, Watercress nasturtium, Wet fields
Cosmetic purposes Fragrance, Tonic

Safety Information

Safety information

European information :
Most important hazard(s):
Xi - Irritant
R 38 - Irritating to skin.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 5600 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 865, 1974.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
(E)-2-hexen-1-al Max. Found: trace to
geraniol Max. Found: 1.2 % and Reason: Sensitization
Recommendation for clary sage oil russia usage levels up to:
15.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -13.00000
beverages(nonalcoholic): -1.80000
beverages(alcoholic): -100.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -20.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -3.90000
fruit ices: -3.90000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -5.30000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8016-63-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1993
WGK Germany:2
salvia sclarea l. oil
Chemidplus:0008016635
RTECS:GF1170000 for cas# 8016-63-5