tobacco oil nicotine-free

Tobacco oil nicotine-free is a plant-derived extract obtained primarily from various Nicotiana species including Nicotiana tabacum and Nicotiana rustica. It appears as a complex oil characterized by a distinctive tobacco odor, widely appreciated in flavor and fragrance industries. Also known by synonyms such as nicotiana rustica oil nicotine-free and denicotinized tobacco oil, this substance provides the sensory qualities of tobacco without the presence of nicotine. The extraction process typically involves removing nicotine to deliver an oil suited for applications needing tobacco aroma without stimulating effects. For detailed chemical information, this compound is referenced under pubchem and linked to the CAS number 73138-76-8. Its derivation from tobacco plants makes it accessible through controlled industrial distillation or solvent extraction methods familiar in botanical oil production.

This oil naturally occurs in species of the Nicotiana genus, such as Nicotiana tabacum and Nicotiana rustica, which are cultivated globally for tobacco production. Tobacco oil nicotine-free serves an important role in flavor and fragrance formulations, delivering tobacco aroma notes without nicotine's pharmacological effects. Its applicability extends to perfuming agents where the smell of tobacco is desired, including in fine fragrances, scented products, and flavor systems under tight regulatory control. Compliance with IFRA (Global) standards ensures its safe incorporation into consumer products, specifying acceptable concentration limits and usage conditions. The oil's nicotine-free status makes it suitable for applications needing tobacco essence while avoiding nicotine-associated restrictions or health concerns.

Tobacco oil nicotine-free exhibits solubility primarily in alcohol, facilitating its use in ethanol-based flavor and fragrance preparations. Its solubility in water is minimal and estimated around 0.4668 mg/L at 25°C, indicating low aqueous dispersibility. The oil's complex composition contributes to its characteristic tobacco scent, rendered stable under typical formulation conditions. Its nonvolatile nicotine-free nature influences volatility and persistence in aromatic blends. These properties dictate its functional integration in perfuming agents and flavors, where solubility, odor profile, and stability govern performance. The oil’s chemical attributes thus inform suitable solvents, formulations, and application methods to maximize sensory impact while maintaining product integrity.

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FAO:	BASIC PRINCIPLES OF STEAM DISTILLATION

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:

flavor and fragrance agents

RIFM Fragrance Material Safety Assessment: Search

IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Safety references

EPI System: View

EPA Substance Registry Services (TSCA):73138-76-8

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

nicotiana tabacum l. oil nicotine-free

Chemidplus:0073138768