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General Material Information

Preferred name alpinia galanga oil
Trivial Name Alpinia galanga, ext.
Short Description greater galanga oil (alpinia galanga)
CAS Number 84625-26-3
ECHA Number 283-399-6
FDA UNII Search
Applications
  • flavor and fragrance agents
Synonyms
  • galanga greater oil (alpinia galanga)
  • greater galanga oil (alpinia galanga)
  • thai galanga oil (alpinia galanga)
  • alpinia galanga l. oil
  • Alpinia galanga, ext.

Occurrences

galangal

Organoleptic Properties

Odor Type: Spicy
General comment At 100.00 %. spicy
Flavor Type: Spicy
General comment Galanga

Potential Uses

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

alpinia galanga l. oil
Pubchem (sid):135284884
Publications by PubMed
New Candidates for Plant-Based Repellents Against Aedes aegypti.
Large Scale Screening of Ethnomedicinal Plants for Identification of Potential Antibacterial Compounds.
Anti-diabetic activity of methanolic extract of Alpinia galanga Linn. aerial parts in streptozotocin induced diabetic rats.
Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods.
Herpes-associated erythema multiforme worsened by a Siddha drug, Alpinia galanga, in an 18-year-old man.
Isolation and screening of endophytes from the rhizomes of some Zingiberaceae plants for L-asparaginase production.
Molecullar and biochemical effect of alcohlic extract of Alpinia galanga on rat spermatogenesis process.
New chalcones bearing a long-chain alkylphenol from the rhizomes of Alpinia galanga.
Chemical composition, antifeedant, repellent, and toxicity activities of the rhizomes of galangal, Alpinia galanga against Asian subterranean termites, Coptotermes gestroi and Coptotermes curvignathus (Isoptera: Rhinotermitidae).
[BIO-INSECTICIDAL ACTIVITY OF ALPINIA GALANGA (L.) ON LARVAL DEVELOPMENT OF SPODOPTERA LITURA (LEPIDOPTERA: NOCTUIDAE).
Inhibitory effect on nitric oxide production and free radical scavenging activity of Thai medicinal plants in osteoarthritic knee treatment.
Effect of selected local medicinal plants on the asexual blood stage of chloroquine resistant Plasmodium falciparum.
Isolation and identification of ingredients inducing cancer cell death from the seeds of Alpinia galanga, a Chinese spice.
An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial.
[Flavonoids from the seeds of Alpinia galanga Willd].
Antiproliferative activity and induction of apoptotic by ethanolic extract of Alpinia galanga rhizhome in human breast carcinoma cell line.
Three new norsesquiterpenoids from the seeds of Alpinia galanga.
Antimicrobial constituents and synergism effect of the essential oils from Cymbopogon citratus and Alpinia galanga.
Identification of seven Zingiberaceous species based on comparative anatomy of microscopic characteristics of seeds.
Evaluating the anti Mycobacterium tuberculosis activity of Alpinia galanga (L.) Willd. axenically under reducing oxygen conditions and in intracellular assays.
Isolation, synthesis and biological evaluation of phenylpropanoids from the rhizomes of Alpania galanga.
Protective effect of Alpinia galanga in STZ induced diabetic nephropathy.
TOXICITY OF ALPINIA GALANGA (ZINGIBERACEAE) RHIZOME EXTRACTS AGAINST SPODOPTERA LITURA (LEPIDOPTERA: NOCTUIDAE).
Central nervous system stimulant actions of Alpinia galanga (L.) rhizome: a preliminary study.
Isolation of bioactive phytoconstituent from Alpinia galanga L. with anti-hyperlipidemic activity.
Galangin Abrogates Ovalbumin-Induced Airway Inflammation via Negative Regulation of NF-κB.
Comparative powder microscopy of Alpinia calcarata Roscoe and Alpinia galanga (Linn.) Willd.
Total and inorganic arsenic contents in some edible zingiberaceous rhizomes in Thailand.
Effect of plant secondary compounds on in vitro methane, ammonia production and ruminal protozoa population.
1'-Acetoxychavicol acetate isolated from Alpinia galanga ameliorates ovalbumin-induced asthma in mice.
Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats.
1'-acetoxychavicol acetate inhibits adipogenesis in 3T3-L1 adipocytes and in high fat-fed rats.
Na⁺-K⁺-ATPase, a potent neuroprotective modulator against Alzheimer disease.
Agrobacterium-mediated transformation in Alpinia galanga (Linn.) Willd. for enhanced acetoxychavicol acetate production.
[Study on eliminating sodium nitrite and blocking nitrosamine synthesis by anthocyanin from skin of Alpinia galanga].
Phenylpropanoids of Alpinia galanga as efflux pump inhibitors in Mycobacterium smegmatis mc² 155.
Anti-Streptococcus mutans efficacy of Thai herbal formula used as a remedy for dental caries.
Bactericidal action of Alpinia galanga essential oil on food-borne bacteria.
The bioflavonoid galangin suppresses the growth of ehrlich ascites carcinoma in Swiss Albino mice: a molecular insight.
Bioefficacy of Alpinia galanga (Zingiberaceae) rhizome extracts, (E)-p-acetoxycinnamyl alcohol, and (E)-p-coumaryl alcohol ethyl ether against Bactrocera dorsalis (Diptera: Tephritidae) and the impact on detoxification enzyme activities.
Current pharmacological and phytochemical studies of the plant Alpinia galanga.
Neuroprotective effect of Alpinia galanga (L.) fractions on Aβ(25-35) induced amnesia in mice.
Direct and indirect organogenesis of Alpinia galanga and the phytochemical analysis.
Isolation of β-sitosterol diglucosyl caprate from Alpinia galanga.
Effect of antimicrobial spice and herb extract combinations on Listeria monocytogenes, Staphylococcus aureus, and spoilage microflora growth on cooked ready-to-eat vacuum-packaged shrimp.
4'-Hydroxycinnamaldehyde from Alpinia galanga (Linn.) induces human leukemic cell apoptosis via mitochondrial and endoplasmic reticulum stress pathways.
Effects of Thai medicinal herb extracts with anti-psoriatic activity on the expression on NF-κB signaling biomarkers in HaCaT keratinocytes.
Ethnobotanical survey of medicinal plants commonly used by Kani tribals in Tirunelveli hills of Western Ghats, India.
Neurotransmitter metabolic enzymes and antioxidant status on Alzheimer's disease induced mice treated with Alpinia galanga (L.) Willd.
Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga.
Analgesic effect of extracts of Alpinia galanga rhizome in mice.
Synergistic antimicrobial activity of galangal (Alpinia galanga), rosemary (Rosmarinus officinalis) and lemon iron bark (Eucalyptus staigerana) extracts.
Alpinia galanga extracts downregulate interleukin-1β-induced matrix metalloproteinases expression in human synovial fibroblasts.
Dose-dependent effect of galangin on fructose-mediated insulin resistance and oxidative events in rat kidney.
Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd.
Chemical diversity in the genus Alpinia (Zingiberaceae): comparative composition of four Alpinia species grown in Northern India.
Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts.
Antibacterial activity of Thai herbal extracts on acne involved microorganism.
Potential mechanisms of hypocholesterolaemic effect of Thai spices/dietary extracts.
Antibacterial activity of Alpinia galanga (L) Willd crude extracts.
Halogenated analogs of 1'-acetoxychavicol acetate, Rev-export inhibitor from Alpinia galanga, designed from mechanism of action.
Impact of Alpinia galanga rhizome extract on Bactrocera dorsalis population.
An ethnobotanical study of traditional anti-inflammatory plants used by the Lohit community of Arunachal Pradesh, India.
Antiplasmid activity of 1'-acetoxychavicol acetate from Alpinia galanga against multi-drug resistant bacteria.
Acetoxybenzhydrols as highly active and stable analogues of 1'S-1'-acetoxychavicol, a potent antiallergic principal from Alpinia galanga.
New Rev-export inhibitor from Alpinia galanga and structure-activity relationship.
Modulation of antioxidant defense by Alpinia galanga and Curcuma aromatica extracts correlates with their inhibition of UVA-induced melanogenesis.
Anti-inflammatory activity of p-coumaryl alcohol-gamma-O-methyl ether is mediated through modulation of interferon-gamma production in Th cells.
Effect of naturally occurring hydroxychavicol acetate on the cytokine production in T helper cells.
The effects of p-hydroxycinnamaldehyde from Alpinia galanga extracts on human chondrocytes.
The effect of water activity and storage temperature on the growth of Aspergillus flavus in medicinal herbs.
Inhibition of in vitro cytotoxic effect evoked by Alpinia galanga and Alpinia officinarum on PC - 3 cell line.
A pharmacognostical report on the rhizome of Alpinia galanga Linn. (Willd).
Antibacterial effect of five Zingiberaceae essential oils.
Structure-activity relationships of 1'-acetoxychavicol acetate homologues as new nuclear export signal inhibitors.
Cytotoxicity, apoptosis and DNA damage induced by Alpinia galanga rhizome extract.
Ethnoveterinary study for antidermatophytic activity of Piper betle, Alpinia galanga and Allium ascalonicum extracts in vitro.
Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.
Inhibition of viral proteases by Zingiberaceae extracts and flavones isolated from Kaempferia parviflora.
1'S-1'-acetoxychavicol acetate isolated from Alpinia galanga inhibits human immunodeficiency virus type 1 replication by blocking Rev transport.
Erythema multiforme-like generalized allergic contact dermatitis caused by Alpinia galanga.
The anti-amoebic activity of some medicinal plants used by AIDS patients in southern Thailand.
Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants.
Antifungal activities of extracts from Thai medicinal plants against opportunistic fungal pathogens associated with AIDS patients.
In vitro enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan.
Inhibitors of nitric oxide production from the rhizomes of Alpinia galanga: structures of new 8-9' linked neolignans and sesquineolignan.
Cytotoxicity of plants from Malaysia and Thailand used traditionally to treat cancer.
Biological effects of indigenous medicinal plants Curcuma longa and Alpinia galanga.
1'S-1'-Acetoxychavicol acetate as a new type inhibitor of interferon-beta production in lipopolysaccharide-activated mouse peritoneal macrophages.
Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
Ginger extract components suppress induction of chemokine expression in human synoviocytes.
Platelet-activating factor (PAF) receptor-binding antagonist activity of Malaysian medicinal plants.
Ginger extract inhibits beta-amyloid peptide-induced cytokine and chemokine expression in cultured THP-1 monocytes.
The in vitro anti-giardial activity of extracts from plants that are used for self-medication by AIDS patients in southern Thailand.
Analysis of the essential oils of the leaves, stems, rhizomes and roots of the medicinal plant Alpinia galanga from southern India.
Immunostimulating activity of the hot water-soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galanga and Citrullus colocynthis.
Antiallergic principles from Alpinia galanga: structural requirements of phenylpropanoids for inhibition of degranulation and release of TNF-alpha and IL-4 in RBL-2H3 cells.
Gastroprotective effects of phenylpropanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action.
Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo).
Hypoglycaemic activity of Alpinia galanga rhizome and its extracts in rabbits.
Effects of a ginger extract on knee pain in patients with osteoarthritis.
Characters of nrDNA ITS region sequences of fruits of Alpinia galanga and their adulterants.
Isolation and identification of trans-2- and trans-3-hydroxy-1,8-cineole glucosides from Alpinia galanga.
Antioxidative/Antimicrobial effects of galangal and alpha-tocopherol in minced beef.
Enantiomeric purity and odor characteristics of 2- and 3-acetoxy-1, 8-cineoles in the rhizomes of Alpinia galanga willd.
Hypolipidemic effect ofAlpinia galanga (Rasna) andKaempferia galanga (Kachoori).
Antifungal activity from Alpinia galanga and the competition for incorporation of unsaturated fatty acids in cell growth.
Toxicity studies on Alpinia galanga and Curcuma longa.
Cytotoxic and antifungal diterpenes from the seeds of Alpinia galanga.
Antitumour principles from Alpinia galanga.
Acetoxychavicol Acetate, an Antifungal Component of Alpinia galanga1.
Acetoxychavicol acetate, an antifungal component of Alpinia galanga.
Constituents from seeds of Alpinia galanga Wild, and their anti-ulcer activities.
Screening of indigenous plants for anthelmintic action against human Ascaris lumbricoides: Part--II.
Expectorant activity of Alpinia galanga Willd.
Antibacterial properties of volatile principles from Alpinia galanga and Acorus calamus.
Pharmacological action of some common essential/oil-bearing plants used in indigenous medicine. II. Pharmacological action of Alpinia galanga, Pistacia integrima, Piper betel and Nardostychas jatamansi.

Other Information

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water No

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for alpinia galanga oil usage levels up to:
0.1000 % in the fragrance concentrate.

Safety references

ClinicalTrials.gov:search
Daily Med:search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
alpinia galanga l. oil
Chemidplus:0084625263