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General Material Information

Preferred name calamus leaf oil
Trivial Name Oils, Acorus calamus
Short Description acorus calamus leaf oil
CAS Number 8015-79-0
FDA UNII Search
COE Number 13
FDA Mainterm 8015-79-0 ; CALAMUS OIL--PROHIBITED
Synonyms
  • acorus americanus leaf oil
  • acorus angustatus leaf oil
  • acorus angustifolius leaf oil
  • acorus asiaticus leaf oil
  • acorus calamus leaf oil
  • acorus calamus var. americanus leaf oil
  • acorus calamus var. angustatus leaf oil
  • acorus calamus var. angustifolius leaf oil
  • acorus calamus var. spurius leaf oil
  • acorus calamus var. verus leaf oil
  • acorus calamus var. vulgaris leaf oil
  • acorus cochinchinensis leaf oil
  • acorus griffithii leaf oil
  • acorus spurius leaf oil
  • acorus triqueter leaf oil
  • acorus verus leaf oil
  • orontium cochinchinense leaf oil
  • Oils, Acorus calamus
  • Calamus oil
  • Oil of sweet flag
  • Sweet flag Oil
  • Oil of Calamus
  • Oils, calamus

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Other Information

FDA Substances Added to Food (formerly EAFUS):View
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water No

Organoleptic Properties

Odor Type: Spicy
spicy, clove, calamus
General comment At 100.00 %. spicy clove

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-guinea pig LD50 297 mg/kg
BEHAVIORAL: TETANY BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Antibiotics and Chemotherapy Vol. 7, Pg. 378, 1957.

intraperitoneal-mouse LD50 177 mg/kg
Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 163, 1959.

intravenous-mouse LD50 1138 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Dissertationes Pharmaceuticae. Vol. 16, Pg. 447, 1964.

intraperitoneal-rat LD50 221 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.

oral-rat LD50 777 mg/kg
BEHAVIORAL: TREMOR
Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

Dermal Toxicity:
skin-guinea pig LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 15, Pg. 623, 1977.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
cis- and trans-Asarone as such should not be used as fragrance ingredients; essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in consumer products.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
methyl eugenol Max. Found:
Recommendation for calamus leaf oil usage levels up to:
3.0000 % in the fragrance concentrate.
Recommendation for calamus leaf oil flavor usage levels up to:
not for flavor use.

Safety references

Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8015-79-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
acorus calamus l. leaf oil
Chemidplus:0008015790