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ocimum basilicum leaf oil

General Material Information

Preferred name	ocimum basilicum leaf oil
Trivial Name	Oils, basil
Short Description	sweet basil leaf oil
CAS Number	8015-73-4
FEMA Number	2119
FDA UNII	Search
MDL	MFCD00217166
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	8015-73-4 ; BASIL, OIL (OCIMUM BASILICUM L.)
Synonyms	sweet basil leaf oil ocimum basilicum l. herb oil Oils, basil Basil oil Oil of Basil Ocimum basilicum oil

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Literature & References

	ocimum basilicum l. herb oil
Canada Domestic Sub. List:	8015-73-4
Pubchem (sid):	135362711

Publications by PubMed
Oral supplementation of Ocimum basilicum has the potential to improves the locomotory, exploratory, anxiolytic behavior and learning in adult male albino mice.
The effects of different UV-B radiation intensities on morphological and biochemical characteristics in Ocimum basilicum L.
Variation in essential oil composition within individual leaves of sweet basil (Ocimum basilicum L.) is more affected by leaf position than by leaf age.
Chemical composition and larvicidal activity of essential oil from Ocimum basilicum (L.) against Culex tritaeniorhynchus, Aedes albopictus and Anopheles subpictus (Diptera: Culicidae).
Mosquitocidal and antiplasmodial activity of Senna occidentalis (Cassiae) and Ocimum basilicum (Lamiaceae) from Maruthamalai hills against Anopheles stephensi and Plasmodium falciparum.
Stomatal density and metabolic determinants mediate salt stress adaptation and water use efficiency in basil (Ocimum basilicum L.).
Effect of Methanolic Leaf Extract of Ocimum basilicum L. on Benzene-Induced Hematotoxicity in Mice.
Photoprotection by foliar anthocyanins mitigates effects of boron toxicity in sweet basil (Ocimum basilicum).
Aqueous and ethanolic leaf extracts of Ocimum basilicum (sweet basil) protect against sodium arsenite-induced hepatotoxicity in Wistar rats.
Partial defoliation and hydraulic integration in Ocimum basilicum (Lamiaceae): testing a model for sectored xylem flow using ¹⁵N labeling.
Characterisation of organic and conventional sweet basil leaves using chromatographic and flow-injection mass spectrometric (FIMS) fingerprints combined with principal component analysis.
Effect of climate change on Alternaria leaf spot of rocket salad and black spot of basil under controlled environment.
Phenylpropanoid biosynthesis in leaves and glandular trichomes of basil (Ocimum basilicum L.).
Antibacterial properties of essential oils and methanol extracts of sweet basil Ocimum basilicum occurring in Bangladesh.
Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach papillomagenesis.
Ocimum basilicum L.: phenolic profile and antioxidant-related activity.
Somatic embryogenesis and plant regeneration from leaf callus of Ocimum basilicum L.
Light suppresses sporulation and epidemics of Peronospora belbahrii.
Epidermal coumaroyl anthocyanins protect sweet basil against excess light stress: multiple consequences of light attenuation.
Evaluation of antileishmanial activity of South Indian medicinal plants against Leishmania donovani.
Root internalization, transport and in-planta survival of Salmonella enterica serovar Newport in sweet basil.
Anthocyanin inheritance and instability in purple basil (Ocimum basilicum L.).
In vitro rosmarinic acid accumulation in sweet basil (Ocimum basilicum L.).
Light reflected from colored mulches affects aroma and phenol content of sweet basil (Ocimum basilicum L.) leaves.
Effects of three AM fungi on growth, distribution of glandular hairs, and essential oil production in Ocimum basilicum L. var. Genovese.
Scale-up micropropagation of sweet basil (Ocimum basilicum L.) in an airlift bioreactor and accumulation of rosmarinic acid.
Chemical characterization of basil (Ocimum basilicum L.) found in local accessions and used in traditional medicines in Iran.
4-coumarate: CoA ligase partitions metabolites for eugenol biosynthesis.
Deployment of municipal solid wastes as a substitute growing medium component in marigold and basil seedlings production.
In vitro antiplasmodial effect of ethanolic extracts of traditional medicinal plant Ocimum species against Plasmodium falciparum.
Use of a common laboratory glassware detergent improves recovery of Cryptosporidium parvum and Cyclospora cayetanensis from lettuce, herbs and raspberries.
Evaluation of the gastric antiulcerogenic effects of Solanum nigrum, Brassica oleracea and Ocimum basilicum in rats.
Biosynthesis of estragole and methyl-eugenol in sweet basil (Ocimum basilicum L). Developmental and chemotypic association of allylphenol O-methyltransferase activities.
The formulation of an effective topical antibacterial product containing Ocimum gratissimum leaf essential oil.
Radioprotective effect of leaf extract of Indian medicinal plant Ocimum sanctum.
Guard cell apoplastic photosynthate accumulation corresponds to a phloem-loading mechanism.
Rapid staining method to detect and identify downy mildew (Peronospora belbahrii) in basil.
Protection of cadmium chloride induced DNA damage by Lamiaceae plants.
Interaction of Salmonella enterica with basil and other salad leaves.
An investigation of the storage and biosynthesis of phenylpropenes in sweet basil.
Characterization of geraniol synthase from the peltate glands of sweet basil.
Antidiarrhoeal activities of Ocimum gratissimum (Lamiaceae).
Antimelanoma and radioprotective activity of alcoholic aqueous extract of different species of Ocimum in C(57)BL mice.
Anti-proliferative activity of essential oil extracted from Thai medicinal plants on KB and P388 cell lines.
Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus.
Phylogeny and evolution of basils and allies (Ocimeae, Labiatae) based on three plastid DNA regions.
Enantiomeric composition of (3R)-(-)- and (3S)-(+)-linalool in various essential oils of Indian origin by enantioselective capillary gas chromatography-flame ionization and mass spectrometry detection methods.
Folklore therapeutic indigenous plants in periodontal disorders in India (review, experimental and clinical approach).
Activity of essential oils and individual components against acetyl- and butyrylcholinesterase.
Study of ambient ozone phytotoxicity in Ukraine and ozone protective effect of some antioxidants.

Other Information

FDA Substances Added to Food (formerly EAFUS):	View
Typical G.C.
Wikipedia:	View
FAO:	BASIC PRINCIPLES OF STEAM DISTILLATION

Suppliers

Golden Frog Trading Manufacturing

PhysChem Properties

Material listed in food chemical codex	No
Solubility
water, 332.1 mg/L @ 25 °C (est)	Yes

Organoleptic Properties

Odor Type: Licorice
basil, herbal, tarragon
General comment	At 100.00 %. basil
Flavor Type: Licorice
basil, licorice, tarragon
General comment	Basil

Occurrences

Potential Uses

Applications	flavor and fragrance agents
Flavoring purposes	Tonic
Cosmetic purposes	Fragrance, Tonic

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1400 mg/kg Food and Cosmetics Toxicology. Vol. 11, Pg. 867, 1973.
Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 11, Pg. 867, 1973.
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Sensitization
IFRA fragrance material specification:
	Linalool and natural products known to be rich in linalool, such as bois de rose, coriander or ho wood oil, should only be used when the level of peroxides is kept to the lowest practical level. It is recommended to add antioxidants at the time of production of the raw material. The addition of 0.1% BHT or alpha-tocopherol for example has shown great efficiency. The maximum peroxide level for products in use should be 20 mmol/l.
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
estragol	Max. Found:
eugenol	Max. Found:
methyl eugenol	Max. Found:
para-anisaldehyde	Max. Found: 0.1 % and Reason: Sensitization

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
		average usual ppm	average maximum ppm
baked goods:		-	4.20000
beverages(nonalcoholic):		-	2.00000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	15.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	2.70000
fruit ices:		-	2.70000
gelatins / puddings:		-	0.01000
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	6.20000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	24.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

Safety references

EPI System: View

Chemical Carcinogenesis Research Information System:Search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):8015-73-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

ocimum basilicum l. herb oil

Chemidplus:0008015734

RTECS:CR3325000 for cas# 8015-73-4