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citrus bergamia risso leaf oil

General Material Information

Preferred name citrus bergamia risso leaf oil
Trivial Name Citrus bergamia, ext.
Short Description essential oil obtained from the leaves of the bergamot, citrus bergamia risso, rutaceae
CAS Number 89957-91-5
ECHA Number 289-612-9
FDA UNII Search
Synonyms
  • bergamot leaf oil (citrus bergamia risso)
  • bergamot petitgrain oil (citrus bergamia risso)
  • essential oil obtained from the leaves of the bergamot, citrus bergamia risso, rutaceae
  • petitgrain bergamot oil (citrus bergamia risso)
  • Citrus bergamia, ext.
  • Bergamot, ext.

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Literature & References

citrus bergamia risso leaf oil
Canada Domestic Sub. List:89957-91-5
Pubchem (sid):135321156
Publications by PubMed
Citrus bergamia essential oil: from basic research to clinical application.
Role of D-Limonene in autophagy induced by bergamot essential oil in SH-SY5Y neuroblastoma cells.
Citrus bergamia Risso Elevates Intracellular Ca (2+) in Human Vascular Endothelial Cells due to Release of Ca (2+) from Primary Intracellular Stores.
Implication of limonene and linalyl acetate in cytotoxicity induced by bergamot essential oil in human neuroblastoma cells.
The essential oil of Citrus bergamia Risso induces vasorelaxation of the mouse aorta by activating K(+) channels and inhibiting Ca(2+) influx.
Bergamot essential oil differentially modulates intracellular Ca2+ levels in vascular endothelial and smooth muscle cells: a new finding seen with fura-2.
Protective effects of an extract from Citrus bergamia against inflammatory injury in interferon-γ and histamine exposed human keratinocytes.
Toxic profile of bergamot essential oil on survival and proliferation of SH-SY5Y neuroblastoma cells.
In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins.
In vitro protective effects of two extracts from bergamot peels on human endothelial cells exposed to tumor necrosis factor-alpha (TNF-alpha).
Neuropharmacology of the essential oil of bergamot.
Effects of systemic administration of the essential oil of bergamot (BEO) on gross behaviour and EEG power spectra recorded from the rat hippocampus and cerebral cortex.
Prevention of Glutamate Accumulation and Upregulation of Phospho-Akt may Account for Neuroprotection Afforded by Bergamot Essential Oil against Brain Injury Induced by Focal Cerebral Ischemia in Rat.
Intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.
Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry.
Cell signaling pathways in the mechanisms of neuroprotection afforded by bergamot essential oil against NMDA-induced cell death in vitro.
Enzymatic hydrolysis of flavonoids and pectic oligosaccharides from bergamot (Citrus bergamia Risso) peel.
Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction.
Effects of rootstock on the composition of bergamot (Citrus bergamia Risso et Poiteau) essential oil.
Toxic effects of six plant oils alone and in combination with controlled atmosphere on Liposcelis bostrychophila (Psocoptera: Liposcelididae).
Studies on the genotoxic properties of essential oils with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay.

Other Information

Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water, 20.12 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Floral
petitgrain, floral
General comment At 100.00 %. petitgrain

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Phototoxicity
IFRA fragrance material specification:
Where the bergapten (5-methoxypsoralen) content of all relevant oils present in a compound has been determined, it is recommended that for applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, the total level of bergapten in the consumer products should not exceed 0.0015% (15 ppm). This is equivalent to 0.0075% (75 ppm) in a fragrance compound used at 20% in the consumer product. Where the level of bergapten has not been determined by appropriate methods, the limits specified in the guidelines on individual oils should apply. In those cases, where such oils are used in combination with other phototoxic ingredients, the additive effect has to be taken into consideration and the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic fragrance ingredients, expressed in % of their recommended maximum level in the consumer product, shall not exceed 100.
Recommendation for citrus bergamia risso leaf oil flavor usage levels up to:
not for flavor use.

Safety references

EPI System: View
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EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
citrus bergamia risso leaf oil
Chemidplus:0089957915