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hop cone oil

General Material Information

Trivial Name hop cone oil
Short Description volatile oil obtained from the freshly dried membranous cones of the female plants of the hops, humulus lupulus l., cannabidaceae
CAS Number 8007-04-3
FEMA Number 2580
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
Synonyms
  • humulus lupulus cone oil
  • volatile oil obtained from the freshly dried membranous cones of the female plants of the hops, humulus lupulus l., cannabidaceae

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Literature & References

humulus lupulus l. cone oil
Canada Domestic Sub. List:8007-04-3
Pubchem (sid):135306977
Publications by PubMed
Quantitative genetic parameters for yield, plant growth and cone chemical traits in hop (Humulus lupulus L.).
Antiadherent and antibiofilm activity of Humulus lupulus L. derived products: new pharmacological properties.
Quantitative trait loci in hop (Humulus lupulus L.) reveal complex genetic architecture underlying variation in sex, yield and cone chemistry.
Increase in cone biomass and terpenophenolics in hops ( Humulus lupulus L.) by treatment with prohexadione-calcium.
The extract from hop cones (Humulus lupulus) as a modulator of oxidative stress in blood platelets.
Varietal characterization of hop (Humulus lupulus L.) by GC-MS analysis of hop cone extracts.
Capillary zone electrophoresis method for determination of bitter (alpha- and beta-) acids in hop (Humulus lupulus L.) cone extracts.
Effects of powdery mildew fungicide programs on twospotted spider mite (Acari: Tetranychidae), hop aphid (Hemiptera: Aphididae), and their natural enemies in hop yards.
DNA sequence and expression variation of hop (Humulus lupulus) valerophenone synthase (VPS), a key gene in bitter acid biosynthesis.
Gold binding by native and chemically modified hops biomasses.
Efficient extraction of high-quality total RNA from various hop tissues (Humulus lupulus L.).
Comparative chemical attributes of native North American hop, Humulus lupulus var. lupuloides E. Small.
Phlorisovalerophenone synthase, a novel polyketide synthase from hop (Humulus lupulus L.) cones.
[The influence of gibberellic acid on the flower and cone development in hop (Humulus lupulus L.)].

PhysChem Properties

Material listed in food chemical codex No
Solubility
alcohol Yes
water No

Organoleptic Properties

Odor Type: Herbal
hops
General comment Hops
Flavor Type: Herbal
hops
General comment Hops

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 3500 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

oral-rat LD50 2700 mg/kg
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -2.90000
beverages(nonalcoholic): -1.70000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -2.20000
condiments / relishes: 20.0000035.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.70000
fruit ices: -1.70000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -2.50000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
EPA Substance Registry Services (TSCA):8007-04-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
humulus lupulus l. cone oil
Chemidplus:0008007043