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General Material Information

Preferred name cinnamon bark oil
Trivial Name Cinnamon bark oil
Short Description volatile oil expressed from the bark of the ceylon cinnamon, cinnamomum zeylanicum, lauraceae
CAS Number 8015-91-6
FEMA Number 2291
FDA UNII Search
MDL MFCD00130805
COE Number 133
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8007-80-5 ; CINNAMON BARK, OIL (CINNAMOMUM SPP.)
Synonyms
  • cinnamom bark EO (30%ald.)
  • cinnamom bark EO (40%ald.)
  • cinnamom bark EO (60%ald.)
  • cinnamomum verum bark oil
  • cinnamomum zeylanicum bark oil
  • cinnamon bark essential FLG (IFF)
  • cinnamon bark essential oil
  • cinnamon bark oil (50% cinnamic aldehyde)
  • cinnamon bark oil (60% cinnamic aldehyde)
  • cinnamon bark oil extra FCC
  • cinnamon bark oil FCC
  • cinnamon bark oil natural
  • cinnamon ess nat 01
  • cinnamon ess nat 02
  • cinnamon ess nat 03
  • cinnamon low coumarin EO
  • volatile oil expressed from the bark of the ceylon cinnamon, cinnamomum zeylanicum, lauraceae
  • Cinnamon oil
  • Oils, cinnamon
  • Oils, essential, cinnamon
  • Essential oils, cinnamon
  • Oils, essential, cinnamon leaf
  • Essential oils, cinnamon leaf
  • Ceylon cinnamon bark oil
  • Cinnamon bark oil, Ceylon
  • Cinnamon oil, Ceylon
  • Artificial cinnamon oil
  • Cinnamon oil, artificial
  • Oils, Cinnamomum zeylanicum
  • Cinnamomum zeylanicum oil
  • Cinnamon leaf oil
  • Cinnamomum zeylanicum leaf oil
  • Ceylon cinnamon leaf oil
  • Oils, Ceylon cinnamon leaf
  • Oils, Ceylon cinnamon bark
  • Cinnamomum oil
  • Cinnamomum leaf oil
  • Cinnamomum oils
  • Cinnamon bark oils
  • Oleum Cinnamomi

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Literature & References

cinnamomum verum bark oil
Canada Domestic Sub. List:8015-91-6
Pubchem (sid):135346120
Publications by PubMed
Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.
Discovery of a novel anti-cancer agent targeting both topoisomerase I and II in hepatocellular carcinoma Hep 3B cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.
Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo.
Invitro Anti-mycotic Activity of Hydro Alcoholic Extracts of Some Indian Medicinal Plants against Fluconazole Resistant Candida albicans.
Anthelmintic activity of trans-cinnamaldehyde and A- and B-type proanthocyanidins derived from cinnamon (Cinnamomum verum).
Empirical prediction and validation of antibacterial inhibitory effects of various plant essential oils on common pathogenic bacteria.
Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.
Authentication of true cinnamon (Cinnamon verum) utilising direct analysis in real time (DART)-QToF-MS.
Antibacterial Mode of Action of Cinnamomum verum Bark Essential Oil, Alone and in Combination with Piperacillin, Against a Multi-Drug-Resistant Escherichia coli Strain.
Antimicrobial activity of the bioactive components of essential oils from Pakistani spices against Salmonella and other multi-drug resistant bacteria.
Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States.
Assessment of coumarin levels in ground cinnamon available in the Czech retail market.
Evaluation of traditional Indian antidiabetic medicinal plants for human pancreatic amylase inhibitory effect in vitro.
Functional and ultrastructural changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Cinnamomum verum essential oil.
Comparison of bacteriostatic and bactericidal activity of 13 essential oils against strains with varying sensitivity to antibiotics.
From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark.
Does the taste matter? Taste and medicinal perceptions associated with five selected herbal drugs among three ethnic groups in West Yorkshire, Northern England.
Antimicrobial effects of selected plant essential oils on the growth of a Pseudomonas putida strain isolated from meat.
Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume.
Anti-oxidant effects of cinnamon (Cinnamomum verum) bark and greater cardamom (Amomum subulatum) seeds in rats fed high fat diet.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.29.6000
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION
FAO:CINNAMOMUM OILS (INCLUDING CINNAMON AND CASSIA)

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 8.404 to 8.571
Refractive Index 1.573 to 1.591 @ 20 °C
Flash Point TCC Value 71.11 °C TCC
Solubility
alcohol Yes
water, 2150 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Spicy
spicy, aldehydic, aromatic, cinnamyl, woody, resinous, honey, powdery
Odor strength medium , recommend smelling in a 10.00 % solution or less
Substantivity 372 hour(s) at 100.00 %
General comment At 10.00 % in dipropylene glycol. sweet spicy aldehydic aromatic cinnamyl woody resinous honey powdery
Flavor Type: Spicy
spicy, sweet, aromatic, aldehydic, honey, cinnamyl, woody, resinous
General comment Spicy sweet aromatic aldehydic honey cinnamyl woody resinous

Occurrences

Safety Information

Safety information

Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 2650 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 749, 1975.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 749, 1975.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
benzaldehyde Max. Found: 0.2 % and Reason: Sensitization
benzyl benzoate Max. Found: 0.6 % and Reason: Sensitization
cinnamyl alcohol Max. Found: 0.3 % and Reason: Sensitization
cinnamaldehyde Max. Found: 75.00 % and Reason: Sensitization
coumarin Max. Found: 0.6 % and Reason: Sensitization
eugenol Max. Found: 2.00 % and Reason: Sensitization
isoeugenol Max. Found: 0.02 % and Reason: Sensitization
ortho-methoxycinnamaldehyde Max. Found: 0.5 % and Reason: Sensitization
safrole Max. Found: 0.2 % and Reason: Carcinogenicity
Recommendation for cinnamon bark oil usage levels up to:
6.0000 % in the fragrance concentrate.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -110.00000
beverages(nonalcoholic): -5.50000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -620.00000
condiments / relishes: -25.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -18.00000
fruit ices: -18.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -80.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -50.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

EPI System: View
ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8015-91-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
cinnamomum verum bark oil
Chemidplus:0008015916
RTECS:FL6340000 for cas# 8015-91-6