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trigonella foenum-graecum seed extract

General Material Information

Preferred name trigonella foenum-graecum seed extract
Trivial Name Fenugreek seed extract
Short Description fenugreek seed extract
CAS Number 84625-40-1
FEMA Number 2485
ECHA Number 283-415-1
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 84625-40-1 ; FENUGREEK, EXTRACT (TRIGONELLA FOENUM-GRAECUM L.)
Synonyms
  • fenugreek extract HS 2447 G (Grau)
  • fenugreek extract LS 2409 G (Grau)
  • fenugreek seed 4:1, 25:1 extract
  • fenugreek seed extract
  • fenugreek seed extract natural
  • fenugreek solid extract---roasted
  • phytovital fenugreek
  • trigogenine
  • trigonella foenum graecum seed extract
  • trigonella foenum-graecum l. seed extract
  • Fenugreek, ext.

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Literature & References

trigonella foenum-graecum l. seed extract
Pubchem (sid):135352329
Publications by PubMed
Fenugreek Seed Extract Prevents Fat Deposition in Monosodium Glutamate (MSG)-Obese Rats.
Pharmacokinetics, tissue distribution and excretion study of a furostanol glycoside-based standardized fenugreek seed extract in rats.
Effect of glycosides based standardized fenugreek seed extract in bleomycin-induced pulmonary fibrosis in rats: Decisive role of Bax, Nrf2, NF-κB, Muc5ac, TNF-α and IL-1β.
Trigonella foenum-graceum (Seed) Extract Interferes with Quorum Sensing Regulated Traits and Biofilm Formation in the Strains of Pseudomonas aeruginosa and Aeromonas hydrophila.
Fenugreek seed extract attenuates cisplatin-induced testicular damage in Wistar rats.
Acute and repeated doses (28 days) oral toxicity study of glycosides based standardized fenugreek seed extract in laboratory mice.
Effects of Fenugreek Seed Extract and Swimming Endurance Training on Plasma Glucose and Cardiac Antioxidant Enzymes Activity in Streptozotocin-induced Diabetic Rats.
Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study.
Administration of fenugreek seed extract produces better effects in the glibenclamide-induced inhibition in hepatic lipid peroxidation: An in vitro study.
Safety, efficacy and toxicological evaluation of a novel, patented anti-diabetic extract of Trigonella Foenum-Graecum seed extract (Fenfuro).
Effects of fenugreek (Trigonella foenum-graecum L.) seed on bone mechanical properties in rats.
Fenugreek seed extract inhibit fat accumulation and ameliorates dyslipidemia in high fat diet-induced obese rats.
The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.
Antioxidant, oxidative DNA damage protective and antimicrobial activities of the plant Trigonella foenum-graecum.
Catalytic degradation of organic dyes using biosynthesized silver nanoparticles.
Green synthesis and characterization of selenium nanoparticles and its augmented cytotoxicity with doxorubicin on cancer cells.
A mechanism-based pharmacological evaluation of efficacy of Trigonella foenum graecum (fenugreek) seeds in regulation of dyslipidemia and oxidative stress in hyperlipidemic rats.
Chemomodulatory Effect of Trigonella foenum graecum (L.) Seed Extract on Two Stage Mouse Skin Carcinogenesis.
Fenugreek seed extract treats peripheral neuropathy in pyridoxine induced neuropathic mice.
Study of lipid profile and parieto-temporal lipid peroxidation in AlCl₃ mediated neurotoxicity. Modulatory effect of fenugreek seeds.
Effect of fenugreek seed extract on adriamycin-induced hepatotoxicity and oxidative stress in albino rats.
Aqueous fenugreek seed extract ameliorates adriamycin-induced cytotoxicity and testicular alterations in albino rats.
Effect of fenugreek seeds extract on cyclophosphamide-induced histomorphometrical, ultrastructural and biochemical changes in testes of albino mice.
Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts.
Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity.
The Role of Adrenergic and Angiotensinergic Systems in Vascular Effect of Alcoholic of Extract Trigonella foenum-graecum Seed in Diabetic Rats.
A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects.
A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers.
Antihyperglycemic effect of Trigonella foenum-graecum (fenugreek) seed extract in alloxan-induced diabetic rats and its use in diabetes mellitus: a brief qualitative phytochemical and acute toxicity test on the extract.
Analgesic and anti-inflammatory activities of Trigonella foenum-graecum (seed) extract.
Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice.
Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells.
The hypoglycaemic activity of fenugreek seed extract is mediated through the stimulation of an insulin signalling pathway.
Effects of fenugreek seed extract in obese mice fed a high-fat diet.
Polyphenol-rich extract of fenugreek seeds protect erythrocytes from oxidative damage.
Genotoxicity testing of a fenugreek extract.
Protective effect of fenugreek (Trigonella foenum graecum) seeds in experimental ethanol toxicity.
Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent.
Inhibition of triiodothyronine production by fenugreek seed extract in mice and rats.
Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol.
Effects of a fenugreek seed extract on feeding behaviour in the rat: metabolic-endocrine correlates.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:1302.19.0000
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Odor Type: Herbal
celery, spicy, coumarinic, balsamic, sweet, lovage, opoponax, burnt, roasted, bready, coffee, grain, sesame, whiskey
General comment At 100.00 %. celery spicy coumarinic balsamic sweet lovage opoponax
Mosciano, Gerard P&F 22, No. 1, 57, (1997) Burnt, roasted, bready, coffee, grain, wheat and sesame with a whiskey nuance
Flavor Type: Bready
roasted, bready, grain, savory, vegetable, whiskey
Mosciano, Gerard P&F 22, No. 1, 57, (1997) At 0.01 %. Roasted, bready and grainy with savory, vegetative and whiskey nuances

Occurrences

Potential Uses

Applications
Odor purposes Balsam
Flavoring purposes Bread, Coffee, Maple, Peanut, Sesame, Whiskey
Cosmetic purposes Perfuming agents, Skin conditioning

Safety Information

Safety information

European information :
Most important hazard(s):
Xn - Harmful.
R 20/22 - Harmful by inhalation and if swallowed.
R 42/43 - May cause sensitization by inhalation and skin contact.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -99.00000
beverages(nonalcoholic): -50.00000
beverages(alcoholic): -20.00000
breakfast cereal: --
cheese: --
chewing gum: -7.60000
condiments / relishes: -150.00000
confectionery froastings: -37.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: -85.00000
fruit ices: -85.00000
gelatins / puddings: -30.00000
granulated sugar: --
gravies: --
hard candy: -280.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 40.0000060.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
trigonella foenum-graecum l. seed extract
Chemidplus:0084625401