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marrubium vulgare extract

General Material Information

Preferred name marrubium vulgare extract
Trivial Name Horehound, ext.
Short Description horehound extract
CAS Number 84696-20-8
FEMA Number 2581
ECHA Number 283-638-4
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 84696-20-8 ; HOREHOUND EXTRACT (MARRUBIUM VULGARE L.)
Synonyms
  • extract of the herb of the horehound, marrubium vulgare l., labiatae
  • hoarhound extract (marrubium vulgare)
  • hore hound extract
  • white hore hound wort extract
  • horehound extract
  • white horehound extract
  • horehound extract, solid (marrubium vulgare linne)
  • horehound marrubium vulgare P.E.
  • marrubium vulgare l. extract
  • Horehound, ext.

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Literature & References

marrubium vulgare l. extract
Pubchem (sid):135354729
Publications by PubMed
Chemical constituents of Marrubium vulgare as potential inhibitors of nitric oxide and respiratory burst.
Marrubium vulgare L. methanolic extract inhibits inflammatory response and prevents cardiomyocyte fibrosis in isoproterenol-induced acute myocardial infarction in rats.
Anti-Trypanosoma cruzi activity of 10 medicinal plants used in northeast Mexico.
Cardioprotective effect of methanolic extract of Marrubium vulgare L. on isoproterenol-induced acute myocardial infarction in rats.
Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor γ agonist.
Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants.
Compositional analysis and in vivo anti-diabetic activity of wild Algerian Marrubium vulgare L. infusion.
Gastroprotective activity of methanol extract and marrubiin obtained from leaves of Marrubium vulgare L. (Lamiaceae).
Marrubium vulgare extract inhibits human-LDL oxidation and enhances HDL-mediated cholesterol efflux in THP-1 macrophage.
Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae.
Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells.
Bactericidal activity of organic extracts from Flourensia cernua DC against strains of Mycobacterium tuberculosis.
Mercury bioaccumulation and phytotoxicity in two wild plant species of Almadén area.
Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics.
Comparative study of the antihypertensive activity of Marrubium vulgare and of the dihydropyridine calcium antagonist amlodipine in spontaneously hypertensive rat.
Comparison of the total antioxidant content of 30 widely used medicinal plants of New Mexico.
Preliminary evaluation of the hypoglycemic effect of some Brazilian medicinal plants.
Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat.
Analysis of the antinociceptive properties of marrubiin isolated from Marrubium vulgare.
Analgesic profile of hydroalcoholic extract obtained from Marrubium vulgare.
Antispasmodic effects of hydroalcoholic extract of Marrubium vulgare on isolated tissues.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:1302.19.0000
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Flavor Type: Herbal
horehound, herbal, tea, jammy, fruity, minty
General comment Horehound

Occurrences

Potential Uses

Applications
Other purposes Skin conditioning, Soothing agents
Cosmetic purposes Skin conditioning, Soothing agents

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic and flavor agents
Recommendation for marrubium vulgare extract usage levels up to:
not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -2.00000
beverages(nonalcoholic): -8.70000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -2.00000
fruit ices: -2.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -680.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
marrubium vulgare l. extract
Chemidplus:0084696208