helichrysum italicum flower extract

General Material Information

Preferred name	helichrysum italicum flower extract
Trivial Name	Helichrysum angustifolium, ext.
Short Description	extract of the flowers of the everlasting, helichrysum angustifolium, asteraceae
CAS Number	90045-56-0
FEMA Number	2592
FDA UNII	Search
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	90045-56-0 ; IMMORTELLE, EXTRACT (HELICHRYSUM ANGUSTIFOLIUM DC.)
Synonyms	elicrisina (Vevy) everlasting flower extract extract of the flowers of the everlasting, helichrysum angustifolium, asteraceae helichrysum angustifolium flower extract immortelle flower extract Helichrysum angustifolium, ext.

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Literature & References

	helichrysum italicum flower extract
Pubchem (sid):	135298590

Publications by PubMed
Identification and quantitative determination of the polar constituents in Helichrysum italicum flowers and derived food supplements.
Clinical and mycological evaluation of an herbal antifungal formulation in canine Malassezia dermatitis.
Helichrysum and grapefruit extracts inhibit carbohydrate digestion and absorption, improving postprandial glucose levels and hyperinsulinemia in rats.
Genetic and metabolite diversity of Sardinian populations of Helichrysum italicum.
Helichrysum italicum: from traditional use to scientific data.
Arzanol, a potent mPGES-1 inhibitor: novel anti-inflammatory agent.
Intestinal antispasmodic effects of Helichrysum italicum (Roth) Don ssp. italicum and chemical identification of the active ingredients.
Spectroscopic identification and anti-biofilm properties of polar metabolites from the medicinal plant Helichrysum italicum against Pseudomonas aeruginosa.
Allergic contact dermatitis caused by Helichrysum italicum contained in an emollient cream.
Essential-oil composition of Helichrysum italicum (ROTH) G.DON ssp. italicum from Elba Island (Tuscany, Italy).
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
Chemical composition and possible in vitro phytotoxic activity of Helichrsyum italicum (Roth) Don ssp. italicum.
Volatile chemical composition and bioactivity of six essential oils against the stored food insect Sitophilus zeamais Motsch. (Coleoptera Dryophthoridae).
Genetic variation in Mediterranean Helichrysum italicum (Asteraceae; Gnaphalieae): do disjunct populations of subsp. microphyllum have a common origin?
Reversible inhibition of three important human liver cytochrome p450 enzymes by tiliroside.
Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo.
Protective role of arzanol against lipid peroxidation in biological systems.
Essential oil composition and larvicidal activity of six Mediterranean aromatic plants against the mosquito Aedes albopictus (Diptera: Culicidae).
Partitioning the relative contributions of inorganic plant composition and soil characteristics to the quality of Helichrysum italicum subsp. italicum (Roth) G. Don fil. essential oil.
Geraniol restores antibiotic activities against multidrug-resistant isolates from gram-negative species.
An evaluation of a new approach to the regeneration of Helichrysum italicum (Roth) G. Don, and the molecular characterization of the variation among sets of differently derived regenerants.
Contribution to the analysis of the essential oil of Helichrysum italicum (Roth) G. Don. Determination of ester bonded acids and phenols.
The ecological aspect of ethnobotany and ethnopharmacology of population in Bosnia and Herzegovina.
The importance of a taste. A comparative study on wild food plant consumption in twenty-one local communities in Italy.
Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum.
Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum.
Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation.
Exudate flavonoids in some Gnaphalieae and Inuleae (Asteraceae).
Cytotoxicity and gene induction by some essential oils in the yeast Saccharomyces cerevisiae.
Influence of environmental factors on composition of volatile constituents and biological activity of Helichrysum italicum (Roth) Don (Asteraceae).
Eudesm-5-en-11-ol from Helichrysum italicum essential oil.
Selection of plants for zinc and lead phytoremediation.
Modifications of hydrophobicity, in vitro adherence and cellular aggregation of Streptococcus mutans by Helichrysum italicum extract.
Evaluation of antiherpesvirus-1 and genotoxic activities of Helichrysum italicum extract.
Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside.
Chemical composition, plant genetic differences, and antifungal activity of the essential oil of Helichrysum italicum G. Don ssp. microphyllum (Willd) Nym.
A new dual inhibitor of arachidonate metabolism isolated from Helichrysum italicum.
Helichrysum italicum extract interferes with the production of enterotoxins by Staphylococcus aureus.
Anti-inflammatory and antioxidant properties of Helichrysum italicum.
Antioxidant activity of anti-inflammatory plant extracts.
Genotoxicity and antigenotoxicity of some essential oils evaluated by wing spot test of Drosophila melanogaster.
New acetophenone glucosides isolated from extracts of Helichrysum italicum with antiinflammatory activity.
Effects of Helichrysum italicum extract on growth and enzymatic activity of Staphylococcus aureus.
Phytochemical characterization and radical scavenger activity of flavonoids from Helichrysum italicum G. Don (Compositae).
[Phthalides from Helichrysum italicum].
A new triterpenoid lactone, alpha-amyrin and uvaol from Helichrysum italicum.
[A new natural triterpenic lactone, alpha-amyrin and uvaol from Helichrysum italicum (G. Don)].
[New beta-diketones from Helichrysum italicum G. Don].
[Influence of Petasites officinalis and Helichrysum italicum on hypersecretive states of gastroduodenal ulcer].

Other Information

FDA Substances Added to Food (formerly EAFUS):	View
Export Tariff Code:	1302.19.0000
Wikipedia:	View

Suppliers

Mane	Vege Tech
Vevy Europe

PhysChem Properties

Material listed in food chemical codex

Organoleptic Properties

Odor Type: Caramellic
immortelle
General comment	At 100.00 %. immortelle
Flavor Type: Green
immortelle
General comment	Immortelle

Occurrences

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
	average usual ppm	average maximum ppm
baked goods:	-	15.00000
beverages(nonalcoholic):	-	5.20000
beverages(alcoholic):	-	-
breakfast cereal:	-	-
cheese:	-	-
chewing gum:	-	0.50000
condiments / relishes:	-	-
confectionery froastings:	-	-
egg products:	-	-
fats / oils:	-	-
fish products:	-	-
frozen dairy:	-	16.00000
fruit ices:	-	166.00000
gelatins / puddings:	-	0.01000
granulated sugar:	-	-
gravies:	-	-
hard candy:	-	11.00000
imitation dairy:	-	-
instant coffee / tea:	-	-
jams / jellies:	-	-
meat products:	-	-
milk products:	-	-
nut products:	-	-
other grains:	-	-
poultry:	-	-
processed fruits:	-	-
processed vegetables:	-	-
reconstituted vegetables:	-	-
seasonings / flavors:	-	-
snack foods:	-	-
soft candy:	-	-
soups:	-	-
sugar substitutes:	-	-
sweet sauces:	-	-

Safety references

Daily Med:search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

helichrysum italicum flower extract

Chemidplus:0090045560