We have found 46589 results matching your criteria.
Please wait while we search...

glycyrrhiza glabra root extract

Glycyrrhiza glabra root extract is a licorice-derived ingredient used for flavoring, fragrance, and skin conditioning in cosmetic and food applications.

General Material Description

Glycyrrhiza glabra root extract is a botanical extract obtained from the roots of the licorice plant, Glycyrrhiza glabra L., belonging to the Leguminosae family. Typically appearing as a concentrated natural extract, it exhibits characteristic licorice odor and flavor notes that are sweet and root-like. This material is widely recognized under several synonyms, including licorice root extract and actiphyte of licorice root extract. The extract contains key compounds such as glycyrrhizic acid and is often used in flavoring and cosmetic applications. As a plant-derived substance, detailed information on its structure and properties can be found in public databases like PubChem. The extract is sourced from cultivated licorice roots through solvent extraction methods, ensuring a natural origin for diverse industrial uses.

Occurrence, Applicability & Potential Uses

The extract naturally occurs within the roots of the licorice plant, Glycyrrhiza glabra, a species grown in various regions. Its applications span the cosmetic and flavor industries, where it serves as a flavoring ingredient imparting characteristic sweet licorice notes. In cosmetics, it acts as a skin conditioning agent with emollient, smoothing, and soothing properties, enhancing formulation performance. Flavor and fragrance applications utilize it as a perfuming agent and flavor enhancer. Standards such as FEMA (US) regulate its use in food flavorings, supporting its acceptance and safety. Its multifunctional profile makes it valuable across product categories including baked goods and confectionery, conditioned by established usage limits to maintain safety and consumer acceptability.

Physico-Chemical Properties Summary

Glycyrrhiza glabra root extract exhibits a specific gravity ranging from 0.9913 to 1.0613 measured at 25 °C, indicating a density close to that of water, which facilitates blending in aqueous formulations. Its refractive index lies between 1.34 and 1.39 at 20 °C, reflecting its optical density and purity. The extract requires storage in cool, dry, and light-protected conditions to maintain chemical stability, with a typical shelf-life of at least six months or longer under proper conditions. These properties affect its behavior in product formulations, influencing solubility, dispersion, and sensory characteristics. The extract's physical profile supports its function in emulsions and aqueous systems where appearance and stability are critical.

FAQ

What is glycyrrhiza glabra root extract, and where does it come from?
Glycyrrhiza glabra root extract is derived from the roots of the licorice plant, known scientifically as Glycyrrhiza glabra L., part of the Leguminosae family. It is a natural botanical extract that imparts characteristic sweet licorice-like odor and flavor. It is primarily obtained via solvent extraction of dried licorice roots and is used extensively in flavor, fragrance, and cosmetic applications due to its unique organoleptic properties.
How is glycyrrhiza glabra root extract used and regulated in industries?
The extract is used mainly as a flavoring agent to provide licorice notes in food and beverages, and in cosmetics as a skin conditioning, soothing, and emollient agent. Regulatory bodies including FEMA (US) and IFRA (Global) provide guidelines on its safe levels of use in products. The FEMA Expert Panel classifies it as generally recognized as safe (GRAS) for flavor use, while IFRA standards guide its incorporation in fragrances to ensure consumer safety.
What safety and storage considerations apply to glycyrrhiza glabra root extract?
No significant hazard classifications have been identified under OSHA's Globally Harmonized System criteria. Toxicity studies indicate high oral LD50 values in rodents, suggesting low acute toxicity. The extract should be stored in sealed containers protected from heat, moisture, and light to preserve stability and shelf life, usually at least six months. Safety assessments, including those by RIFM and IFRA, support its use in cosmetics and flavorings following recommended exposure levels.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

Google Scholar Start search
Google Books Start search
Google Patents Start search
Perfumer & Flavorists Start search
EU Patents Start search
PubMeb Start search
NCBI Start search

Literature & References

glycyrrhiza glabra root extract
Pubchem (sid):135314337
Publications by PubMed
Evaluation of sodium benzoate and licorice (Glycyrrhiza glabra) root extract as heat-sensitizing additives against Escherichia coli O157:H7 in mildly heated young coconut liquid endosperm.
Enhancement of Hippocampal CA3 Neuronal Dendritic Arborization by Glycyrrhiza glabra root extract Treatment in Wistar Albino Rats.
Beneficial effect of aqueous root extract of Glycyrrhiza glabra on learning and memory using different behavioral models: An experimental study.
Improving the thrombin inhibitory activity of glycyrrhizin, a triterpenic saponin, through a molecular simplification of the carbohydrate moiety.
Effect of GutGard in the Management of Helicobacter pylori: A Randomized Double Blind Placebo Controlled Study.
Anti-convulsant action and amelioration of oxidative stress by Glycyrrhiza glabra root extract in pentylenetetrazole- induced seizure in albino rats.
Chromolithic method development, validation and system suitability analysis of ultra-sound assisted extraction of glycyrrhizic acid and glycyrrhetinic acid from Glycyrrhiza glabra.
18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice.
Protection of DNA and microsomal membranes in vitro by Glycyrrhiza glabra L. against gamma irradiation.
Immunological studies of Revitonil, a phytopharmaceutical containing Echinacea purpurea and Glycyrrhiza glabra root extract.
Inhibition of human complement by beta-glycyrrhetinic acid.
Transdermal microemulsions of Glycyrrhiza glabra L.: characterization, stability and evaluation of antioxidant potential.
Evaluation of the genotoxic potential of standardized extract of Glycyrrhiza glabra (GutGard™).
Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6.
Memory enhancing activity of Glycyrrhiza glabra in mice.
Screening of traditionally used South African plants for antifungal activity against Candida albicans.
[Differences between the root and rhizome of Ural licorice (Glycyrrhiza uralensis Fisch.) and those of smooth licorice (Glycyrrhiza glabra L.)].

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:1302.12.0000
Wikipedia:View

General Material Information

Preferred name glycyrrhiza glabra root extract
Trivial Name Licorice, Glycyrrhiza glabra, ext.
Short Description extract of the roots of the licorice, glycyrrhiza glabra l., leguminosae
CAS Number 84775-66-6
FEMA Number 2628
ECHA Number 283-895-2
FDA UNII 2788Z9758H
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 68916-91-6 ; LICORICE EXTRACT (GLYCYRRHIZA SPP.)
Synonyms
  • aqua licorice extract P-T
  • extract of the roots of the licorice, glycyrrhiza glabra l., leguminosae
  • glycyrrhiza glabra (mulethi) extract
  • licorice root extract
  • actiphyte of licorice root extract
  • licorice root extract natural
  • licorice root extract, 20% glycyrrhizic acid
  • liquorice kiinote (Omega)
  • liquorice root kiinote organic (Omega)
  • polyol soluble licorice extract HG
  • polyol soluble licorice extract P-T(40)
  • vedaplex 146
  • Licorice, Glycyrrhiza glabra, ext.
  • Glycyrrhiza glabra ext.

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 8.249 to 8.831
Refractive Index 1.34 to 1.39 @ 20 °C
Shelf life 6 months (or longer if stored properly.)
Storage notes Store in cool, dry place in tightly sealed containers, protected from heat and light.

Organoleptic Properties

Odor Type: Licorice
sweet, licorice
General comment At 100.00 %. sweet licorice root
Flavor Type: Licorice
licorice
General comment Licorice

Occurrences

Safety Information

Safety information

Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 14200 mg/kg

intraperitoneal-rat LD50 1420 mg/kg

oral-mouse LD50 > 7500 mg/kg

intraperitoneal-mouse LD50 1500 mg/kg

Dermal Toxicity:
subcutaneous-rat LD50 4200 mg/kg

subcutaneous-mouse LD50 4000 mg/kg

Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -84.00000
beverages(nonalcoholic): -33.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -29000.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -39.00000
fruit ices: -39.00000
gelatins / puddings: -4.00000
granulated sugar: --
gravies: --
hard candy: -130.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
glycyrrhiza glabra root extract
Chemidplus:0084775666