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citrus sinensis peel extract

General Material Information

Preferred name citrus sinensis peel extract
Trivial Name Sweet orange peel oil, valencia
Short Description extract obtained from the fresh epicarps of the sweet orange valencia, citrus sinensis (syn: citrus aurantium dulcis), rutaceae
CAS Number 8008-57-9
FEMA Number 2824
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 977091-82-9 ; ORANGE PEEL, SWEET, EXTRACT (CITRUS SINENSIS (L.) OSBECK)
Synonyms
  • Citrus sinensis peel oil
  • Essential oils, orange
  • Essential oils, orange, sweet
  • extract obtained from the fresh epicarps of the sweet orange valencia, citrus sinensis (syn: citrus aurantium dulcis), rutaceae
  • Fructus citri sinensis essential oil
  • Oil of sweet orange
  • Oils, essential, orange, sweet
  • Oils, orange, sweet
  • Oils, sweet orange peel
  • Orange oil
  • orange oil, extract epicarp, Valencia
  • orange peel extract natural
  • orange peel solid extract
  • orange peel sweet extract
  • Sweet orange oil
  • sweet orange peel extract
  • Sweet orange peel oil

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Literature & References

citrus sinensis peel extract
Canada Domestic Sub. List:8008-57-9
Pubchem (sid):135333547
Publications by PubMed
Biosynthesis of silver and platinum nanoparticles using orange peel extract: characterisation and applications.
Swarm motility of Salmonella enterica serovar Typhimurium is inhibited by compounds from fruit peel extracts.
Orange peel extract, containing high levels of polymethoxyflavonoid, suppressed UVB-induced COX-2 expression and PGE2 production in HaCaT cells through PPAR-γ activation.
Use of orange peel extract for mixotrophic cultivation of Chlorella vulgaris: increased production of biomass and FAMEs.
Amelioration of diabetic nephropathy by orange peel extract in rats.
Effect of different levels of dietary sweet orange (Citrus sinensis) peel extract on humoral immune system responses in broiler chickens.
Oral dose of citrus peel extracts promotes wound repair in diabetic rats.
Citrange fruit extracts alleviate obesity-associated metabolic disorder in high-fat diet-induced obese C57BL/6 mouse.
Citrus peel extract attenuates acute cyanide poisoning-induced seizures and oxidative stress in rats.
Larvicidal, pupicidal, repellent and adulticidal activity of Citrus sinensis orange peel extract against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae).
Increased antioxidant content in juice enriched with dried extract of pomegranate (Punica granatum) peel.
Biosynthesis of silver nanoparticles using citrus sinensis peel extract and its antibacterial activity.
Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines.
Effect of Citrus paradisi extract and juice on arterial pressure both in vitro and in vivo.
Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis.
Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice.
Medicinal values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin, and thyroid hormones.
Antiperoxidative, antithyroidal, antihyperglycemic and cardioprotective role of Citrus sinensis peel extract in male mice.
Apoptosis-inducing activity of hydroxylated polymethoxyflavones and polymethoxyflavones from orange peel in human breast cancer cells.
Chemopreventive effects of orange peel extract (OPE). II: OPE inhibits atypical hyperplastic lesions in rodent mammary gland.
Chemopreventive effects of orange peel extract (OPE). I: OPE inhibits intestinal tumor growth in ApcMin/+ mice.
Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines.
Efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography.
Nobiletin: efficient and large quantity isolation from orange peel extract.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.12.0000
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Odor Type: Citrus
orange
General comment At 100.00 %. orange
Flavor Type: Citrus
orange
General comment Orange

Occurrences

Safety Information

Safety information

Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA fragrance material specification:
d-, l-and dl-Limonene and natural products containing substantial amounts of it, should only be used when the level of peroxides is kept to the lowest practical level, for instance by adding antioxidants at the time of production. Such products should have a peroxide value of less than 20 millimoles peroxides per liter, determined according to the FMA method, which can be downloaded from the IFRA website (see Analytical Methods).
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
citral Max. Found: 0.1 % and Reason: Sensitization
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: 320.00000330.00000
beverages(nonalcoholic): -99.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -170.00000
fruit ices: -170.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 320.00000330.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8008-57-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
citrus sinensis peel extract
Chemidplus:0008008579
EPA/NOAA CAMEO:hazardous materials