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crocus sativus stigma tincture

General Material Information

Preferred name crocus sativus stigma tincture
Trivial Name Saffron, ext.
Short Description saffron stigma tincture
CAS Number 84604-17-1
ECHA Number 283-295-0
FDA UNII Search
Synonyms
  • saffron stigma tincture
  • Saffron, ext.

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Literature & References

crocus sativus l. stigma tincture
Pubchem (sid):135316899
Publications by PubMed
Effects of Saffron (Crocus sativus L.) Stigma Extract and its Active Constituent Crocin on Neuropathic Pain Responses in a Rat Model of Chronic Constriction Injury.
A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression.
Intron retention and rhythmic diel pattern regulation of carotenoid cleavage dioxygenase 2 during crocetin biosynthesis in saffron.
Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia.
Dietary saffron reduced the blood pressure and prevented remodeling of the aorta in L-NAME-induced hypertensive rats.
De novo transcriptome assembly and comprehensive expression profiling in Crocus sativus to gain insights into apocarotenoid biosynthesis.
Potential Ergogenic Effects of Saffron.
Crocin inhibits cell proliferation and enhances cisplatin and pemetrexed chemosensitivity in lung cancer cells.
Safranal as a safe compound to mice immune system.
Safety evaluation of saffron stigma (Crocus sativus L.) aqueous extract and crocin in patients with schizophrenia.
Smooth muscle relaxant activity of Crocus sativus (saffron) and its constituents: possible mechanisms.
Comprehensive transcriptome analysis of Crocus sativus for discovery and expression of genes involved in apocarotenoid biosynthesis.
Saffron: a natural product with potential pharmaceutical applications.
Comparative expression analysis of senescence gene CsNAP and B-class floral development gene CsAP3 during different stages of flower development in Saffron (Crocus sativus L.).
Crocin protects PC12 cells against MPP(+)-induced injury through inhibition of mitochondrial dysfunction and ER stress.
Energy analyses and greenhouse gas emissions assessment for saffron production cycle.
Identification of safranal as the main allelochemical from saffron (Crocus sativus).
Evaluation of antioxidant activities of bioactive compounds and various extracts obtained from saffron (Crocus sativus L.): a review.
The Effect of Crocus sativus L. and Its Constituents on Memory: Basic Studies and Clinical Applications.
Identification, cloning and characterization of an ultrapetala transcription factor CsULT1 from Crocus: a novel regulator of apocarotenoid biosynthesis.
Attenuation of oxidative stress, inflammation and apoptosis by ethanolic and aqueous extracts of Crocus sativus L. stigma after chronic constriction injury of rats.
Attenuation of oxidative stress, inflammation and apoptosis by ethanolic and aqueous extracts of Crocus sativus L. stigma after chronic constriction injury of rats.
New target carotenoids for CCD4 enzymes are revealed with the characterization of a novel stress-induced carotenoid cleavage dioxygenase gene from Crocus sativus.
Comparing the efficacy and safety of Crocus sativus L. with memantine in patients with moderate to severe Alzheimer's disease: a double-blind randomized clinical trial.
Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis.
Proposed cytotoxic mechanisms of the saffron carotenoids crocin and crocetin on cancer cell lines.
Study on diuretic activity of saffron (stigma of Crocus sativus L.) Aqueous extract in rat.
The Effect of Chronic Administration of Saffron (Crocus sativus) Stigma Aqueous Extract on Systolic Blood Pressure in Rats.
Crocus sativus L. (saffron) stigma aqueous extract induces apoptosis in alveolar human lung cancer cells through caspase-dependent pathways activation.
Bioactivity assessment and toxicity of crocin: a comprehensive review.
Relative expression of CsZCD gene and apocarotenoid biosynthesis during stigma development in Crocus sativus L.
Crocins with high levels of sugar conjugation contribute to the yellow colours of early-spring flowering crocus tepals.
Crocus sativus stigma extract and its major constituent crocin possess significant antiproliferative properties against human prostate cancer.
Protective effect of crocin against cerebral ischemia in a dose-dependent manner in a rat model of ischemic stroke.
Increasing the applications of Crocus sativus flowers as natural antioxidants.
A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and antioxidant status.
Effect of aqueous extract of Crocus sativus L. (saffron) stigma against subacute effect of diazinon on specific biomarkers in rats.
Characterization of a glucosyltransferase enzyme involved in the formation of kaempferol and quercetin sophorosides in Crocus sativus.
Quantification of main bioactive metabolites from saffron (Crocus sativus) stigmas by a micellar electrokinetic chromatographic (MEKC) method.
Identification and possible role of a MYB transcription factor from saffron (Crocus sativus).
Developmental and stress regulation of gene expression for a 9-cis-epoxycarotenoid dioxygenase, CstNCED, isolated from Crocus sativus stigmas.
Chemical constituents and bioactivities of the liposoluble fraction from different medicinal parts of Crocus sativus.
In vitro development of microcorms and stigma like structures in saffron (Crocus sativus L.).
Crocetin from the tubular calyx of Nyctanthes arbor-tristis.
Evaluation of Crocus sativus L. stigma phenolic and flavonoid compounds and its antioxidant activity.
Comparative analysis of pistil transcriptomes reveals conserved and novel genes expressed in dry, wet, and semidry stigmas.
Crocus sativus L.: A comprehensive review.
Satiereal, a Crocus sativus L extract, reduces snacking and increases satiety in a randomized placebo-controlled study of mildly overweight, healthy women.
Crocins transport in Crocus sativus: the long road from a senescent stigma to a newborn corm.
Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats.
Effect of Crocus sativus L. (saffron) stigma and its constituents, crocin and safranal, on morphine withdrawal syndrome in mice.
Antidepressant properties of bioactive fractions from the extract of Crocus sativus L.
Cloning and characterization of a glucosyltransferase from Crocus sativus stigmas involved in flavonoid glucosylation.
Metabolite and target transcript analyses during Crocus sativus stigma development.
Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice.
Protective effect of Crocus sativus stigma extract and crocin (trans-crocin 4) on methyl methanesulfonate-induced DNA damage in mice organs.
Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers.
Bacillus subtilis FZB24 affects flower quantity and quality of saffron (Crocus sativus).
Cytosolic and plastoglobule-targeted carotenoid dioxygenases from Crocus sativus are both involved in beta-ionone release.
Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial.
Specific IgG antibodies (total and subclasses) against Saffron pollen: a study of their correlation with specific IgE and immediate skin reactions.
The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats.
An EST database from saffron stigmas.
Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial.
Inhibitory activity on amyloid-beta aggregation and antioxidant properties of Crocus sativus stigmas extract and its crocin constituents.
Effect of Saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats.
Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs.
Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice.
Implications of carotenoid biosynthetic genes in apocarotenoid formation during the stigma development of Crocus sativus and its closer relatives.
Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial.
Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas.
[Physiological and ecological effects of potassium on expansion of crocus corm].
[Induction of petal-like structures from petals of Crocus sativus L. and the differentiation of style-stigma-like structures in vitro].
Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice.
Authentic identification of stigma Croci (stigma of Crocus sativus) from its adulterants by molecular genetic analysis.
Formation of Stigma-Like Structures and Pigment in Cultured Tissues of Crocus sativus.

Other Information

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PhysChem Properties

Material listed in food chemical codex No

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for crocus sativus stigma tincture flavor usage levels up to:
not for flavor use.

Safety references

ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
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EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
crocus sativus l. stigma tincture
Chemidplus:0084604171