ruta graveolens herb extract

Ruta graveolens herb extract, commonly referred to as rue extract or herb-of-grace extract, is a botanical derivative obtained from the leaves and stems of the ruta graveolens plant. It exhibits a distinctive herbal odor profile, which is characteristically green and aromatic. This extract is widely used in fragrance formulations due to its unique sensory properties, contributing aromatic notes reminiscent of fresh herbs. The compound is recognized under multiple synonyms including ruta hortensis herb extract and ruta graveolens P.E., facilitating cross-referencing in various chemical and botanical databases. Detailed chemical information can be found in the PubChem database. Typically, the extract is sourced from the cultivation of ruta graveolens plants, ensuring consistent quality for industrial and cosmetic applications.

Ruta graveolens herb extract naturally occurs in the plant species Ruta graveolens, commonly called rue, which is native to the Mediterranean region and cultivated worldwide for its aromatic foliage. Its use is primarily in fragrance agents, where it imparts a herbal note to perfumes and scented products. The compound has been evaluated under the International Fragrance Association's Code of Practice (IFRA, Global) due to concerns regarding phototoxicity linked to the presence of bergapten, a photosensitizing constituent. Regulatory guidelines recommend limiting bergapten concentrations to ensure consumer safety in products intended for application on skin exposed to sunlight. Beyond perfumery, the extract is not indicated for flavor use, aligning with current safety recommendations and usage directives.

Ruta graveolens herb extract demonstrates properties that influence its application in fragrance formulations. It presents as a botanical extract with a herbal odor, characteristic of its complex mixture of volatile compounds. The extract’s solubility profile favors integration into oil-based and alcoholic solvent systems, common in perfumery. Its chemical stability is affected by exposure to light and heat, necessitating careful formulation to preserve the intensity of its aromatic notes. Additionally, the presence of phototoxic constituents such as bergapten requires consideration during product development, influencing concentration limits and application conditions. Overall, its physicochemical characteristics dictate both performance and regulatory compliance within fragrance applications.

	ruta graveolens l. herb extract
Pubchem (sid):	135276071

Export Tariff Code:	1302.19.0000
Wikipedia:	View

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Phototoxicity
IFRA fragrance material specification:
	Where the bergapten (5-methoxypsoralen) content of all relevant oils present in a compound has been determined, it is recommended that for applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, the total level of bergapten in the consumer products should not exceed 0.0015% (15 ppm). This is equivalent to 0.0075% (75 ppm) in a fragrance compound used at 20% in the consumer product. Where the level of bergapten has not been determined by appropriate methods, the limits specified in the guidelines on individual oils should apply. In those cases, where such oils are used in combination with other phototoxic ingredients, the additive effect has to be taken into consideration and the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic fragrance ingredients, expressed in % of their recommended maximum level in the consumer product, shall not exceed 100.
Recommendation for ruta graveolens herb extract flavor usage levels up to:
	not for flavor use.

Safety references

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

ruta graveolens l. herb extract

Chemidplus:0084929475