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General Material Information

Preferred name pyrus malus fruit extract
Trivial Name Apple, Malus sylvestris, ext.
Short Description extract of the fruit of the apple, pyrus malus l., rosaceae
CAS Number 85251-63-4
ECHA Number 286-475-7
FDA UNII Search
Synonyms
  • fruitapone apple (Symrise)
  • fruitapone apple B (Symrise)
  • apple brandy pure jungle essence
  • apple extract
  • actiphyte of apple extract
  • apple extract (pyrus malus)
  • golden apple extract 60%
  • apple extract HS 1806 AT (Grau)
  • extrapone apple GW (Symrise)
  • wild apple polyphenols
  • bioprotectyl
  • extract of the fruit of the apple, pyrus malus l., rosaceae
  • pyrus malus l. fruit extract
  • Apple, Malus sylvestris, ext.
  • Malus sylvestris ext.

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Literature & References

pyrus malus l. fruit extract
Pubchem (sid):135316389
Publications by PubMed
Preparation of an agar-silver nanoparticles (A-AgNp) film for increasing the shelf-life of fruits.
Inhibition of the intestinal sodium-coupled glucose transporter 1 (SGLT1) by extracts and polyphenols from apple reduces postprandial blood glucose levels in mice and humans.
Apple polyphenol extracts protect against aspirin-induced gastric mucosal damage in rats.
Chemopreventive activity of apple extract following medium-term oral carcinogenesis assay induced by 4-nitroquinoline-1-oxide.
Identification of epicatechin as one of the key bioactive constituents of polyphenol-enriched extracts that demonstrate an anti-allergic effect in a murine model of food allergy.
Intra-laboratory validation of microplate methods for total phenolic content and antioxidant activity on polyphenolic extracts, and comparison with conventional spectrophotometric methods.
Cytotoxicity and antimicrobial activities of green synthesized silver nanoparticles.
Concentration-dependent inhibition of Escherichia coli O157:H7 and heterocyclic amines in heated ground beef patties by apple and olive extracts, onion powder and clove bud oil.
Bioavailability of epicatechin and effects on nitric oxide metabolites of an apple flavanol-rich extract supplemented beverage compared to a whole apple puree: a randomized, placebo-controlled, crossover trial.
Diagnostic usefulness of component-resolved diagnosis by skin prick tests and specific IgE to single allergen components in children with allergy to fruits and vegetables.
Screening of polyphenolic plant extracts for anti-obesity properties in Wistar rats.
Plant extracts, spices, and essential oils inactivate Escherichia coli O157:H7 and reduce formation of potentially carcinogenic heterocyclic amines in cooked beef patties.
Apple polyphenols extract (APE) improves colon damage in a rat model of colitis.
Antimicrobial activity of apple, hibiscus, olive, and hydrogen peroxide formulations against Salmonella enterica on organic leafy greens.
Apple extract induces increased epithelial resistance and claudin 4 expression in Caco-2 cells.
Changes Caused by Fruit Extracts in the Lipid Phase of Biological and Model Membranes.
Sublingual immunotherapy in peach allergy: monitoring molecular sensitizations and reactivity to apple fruit and Platanus pollen.
Polyphenols and phenolic acids from strawberry and apple decrease glucose uptake and transport by human intestinal Caco-2 cells.
Effect of fresh apple extract on glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells in vitro.
Polyphenol-enriched apple extract attenuates food allergy in mice.
Effects of fruit extracts on the formation of acrylamide in model reactions and fried potato crisps.
Impact of apple polyphenols on GSTT2 gene expression, subsequent protection of DNA and modulation of proliferation using LT97 human colon adenoma cells.
Chemical composition and in vitro anti-inflammatory activity of apple phenolic extracts and of their sub-fractions.
Procyanidin C1 from apple extracts inhibits Fc epsilon RI-mediated mast cell activation.
Profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen.
Effects of water-soluble natural antioxidants on photosensitized oxidation of conjugated linoleic acid in an oil-in-water emulsion system.
Inhibitory effect of fruit extracts on the formation of heterocyclic amines.
Select plant tannins induce IL-2Ralpha up-regulation and augment cell division in gammadelta T cells.
Comparison of the relative recovery of polyphenolics in two fruit extracts from a model of degradation during digestion and metabolism.
Apple polyphenols affect protein kinase C activity and the onset of apoptosis in human colon carcinoma cells.
Two different profiles of peach allergy in the north of Spain.
Anti-cancer properties of phenolics from apple waste on colon carcinogenesis in vitro.
PT with heat-processed apple peel extract to detect LTP hypersensitivity.
Mapping of Malus domestica allergens by 2-D electrophoresis and IgE-reactivity.
Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy.
Effect of apple extracts on NF-kappaB activation in human umbilical vein endothelial cells.
Latex-vegetable syndrome due to custard apple and aubergine: new variations of the hevein symphony.
Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics.
Apples increase nitric oxide production by human saliva at the acidic pH of the stomach: a new biological function for polyphenols with a catechol group?
Flow cytometric analysis of in vitro activated basophils, specific IgE and skin tests in the diagnosis of pollen-associated food allergy.
Novel low-density lipoprotein (LDL) oxidation model: antioxidant capacity for the inhibition of LDL oxidation.
Reducing the 137Cs-load in the organism of "Chernobyl" children with apple-pectin.
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
Diagnostic value of scratch-chamber test, skin prick test, histamine release and specific IgE in birch-allergic patients with oral allergy syndrome to apple.
Detection of specific IgE antibodies in the sera of patients allergic to birch pollen using recombinant allergens Bet v 1, Bet v 2, Bet v 4: evaluation of different IgE reactivity profiles.
Clinical role of a lipid transfer protein that acts as a new apple-specific allergen.
On-line solid-phase extraction of triazine herbicides using a molecularly imprinted polymer for selective sample enrichment.
A new apple extract.
Characterization of apple 18 and 31 kd allergens by microsequencing and evaluation of their content during storage and ripening.
Purification and characterization of the major allergen from apple and its allergenic cross-reactivity with Bet v 1.
Effect of hyposensitization for tree pollinosis on associated apple allergy.
Optimization of apple allergen preparation for in vivo and in vitro diagnostics.
Multiplicity of cross-reactive epitopes on Bet v I as detected with monoclonal antibodies and human IgE.
Differences among sibling speciesRhagoletis mendax andR. pomonella (diptera: ephritidae) in their antennal sensitivity to host fruit compounds.
Common epitopes of birch pollen and apples--studies by western and northern blot.
Analysis by reverse-phase high-pressure liquid chromatography of phenylisothiocyanate-derivatized 1-aminocyclopropane-1-carboxylic acid in apple extracts.
Calmodulin inhibitor in senescing apples and its physiological and pharmacological significance.
Devil apple extract and skin cancer.

Other Information

Export Tariff Code:1302.19.0000
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Odor Type: Green
sweet, apple, green, ripe, juicy, estery, cider
General comment At 100.00 %. sweet apple
Mosciano, Gerard P&F 21, No. 1, 33, (1996) Green, sweet apple, ripe applesauce, juicy and estry with a cider-like nuance
Flavor Type: Fruity
apple, apple skin, cider, brown
General comment Apple apple skin cider brown
Mosciano, Gerard P&F 21, No. 1, 33, (1996) At 10.00 ppm. Apple juice, fresh, cider-like and brown

Occurrences

Potential Uses

Applications
Other purposes Skin conditioning
Cosmetic purposes Skin conditioning

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Safety references

Daily Med:search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
pyrus malus l. fruit extract
Chemidplus:0085251634