punica granatum extract

General Material Information

Preferred name	punica granatum extract
Trivial Name	Pomegranate extract
Short Description	extract of the pomegranate, punica granatum l., punicaceae
CAS Number	84961-57-9
ECHA Number	284-646-0
FDA UNII	Search
Synonyms	adandrine extract of the pomegranate, punica granatum l., punicaceae phytovital pomegranate extrapone pomegranate fruitapone pomegranate pomegranate extract pomegranate extract (B)-BG30 pomegranate extract (ellagic 40%) pomegranate extract (water soluble) pomegranate extract ellagic acid pomegranate P.E. punica florida extract punica grandiflora extract punica nana extract punica spinosa extract punica granatum l. extract Pomegranate, ext. Punica granatum ext.

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Literature & References

	punica granatum l. extract
Pubchem (sid):	135300670

Publications by PubMed
Preparation and characterization of standardized pomegranate extract-phospholipid complex as an effective drug delivery tool.
Punica granatum and its therapeutic implications on breast carcinogenesis: A review.
Identification of longevity, fertility and growth-promoting properties of pomegranate in Caenorhabditis elegans.
Antinociceptive and anti-inflammatory activities of a pomegranate (Punica granatum L.) extract rich in ellagitannins.
Ethnobotanical survey of medicinally important shrubs and trees of Himalayan region of Azad Jammu and Kashmir, Pakistan.
Evaluation of antidiabetic, hypolipedimic and antioxidant activity of hydroalcoholic extract of leaves and fruit peel of Punica granatum in male Wistar albino rats.
Evaluation of antioxidant and antiradical properties of Pomegranate (Punica granatum L.) seed and defatted seed extracts.
Growth-Inhibitory and Apoptosis-Inducing Effects of Punica granatum L. var. spinosa (Apple Punice) on Fibrosarcoma Cell Lines.
Effects of Flavonoid-rich Plant Extracts on In vitro Ruminal Methanogenesis, Microbial Populations and Fermentation Characteristics.
Antioxidant and anti-inflammatory activities of pomegranate (Punica granatum) on Eimeria papillata-induced infection in mice.
Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects.
Antioxidant and antibacterial activities of extracts from Conyza bonariensis growing in Yemen.
Pomegranate peel and peel extracts: chemistry and food features.
Assessment of polyphenol coated nano zero valent iron for hexavalent chromium removal from contaminated waters.
Anticonvulsant activity of the ethanolic extract of Punica granatum L. seed.
Osteogenic potential of punica granatum through matrix mineralization, cell cycle progression and runx2 gene expression in primary rat osteoblasts.
Evaluation of the antinociceptive effect of the ethanolic extract of Punica granatum.
Mixed pro- and anti-oxidative effects of pomegranate polyphenols in cultured cells.
Protective effect of Punica granatum peel and Vitis vinifera seeds on DEN-induced oxidative stress and hepatocellular damage in rats.
Lipid Lowering Effect of Punica granatum L. Peel in High Lipid Diet Fed Male Rats.
An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial.
Pomegranate extract modulates processing of amyloid-β precursor protein in an aged Alzheimer's disease animal model.
Pomegranate phenolics inhibit formation of advanced glycation endproducts by scavenging reactive carbonyl species.
Green synthesis of gold nanoparticles using plant extracts as reducing agents.
Antimicrobial Efficacy of Punica granatum mesocarp, Nelumbo nucifera Leaf, Psidium guajava Leaf and Coffea Canephora Extract on Common Oral Pathogens: An In-vitro Study.
Punica granatum cv. Dente di Cavallo seed ethanolic extract: antioxidant and antiproliferative activities.
Marker based standardization of polyherbal formulation (SJT-DI-02) by high performance thin layer chromatography method.
Amelioration of Diabetes and Painful Diabetic Neuropathy by Punica granatum L. Extract and Its Spray Dried Biopolymeric Dispersions.
Potential anti-inflammatory effects of the hydrophilic fraction of pomegranate (Punica granatum L.) seed oil on breast cancer cell lines.
Small molecule inhibitors of HCV replication from pomegranate.
Triterpenes as uncompetitive inhibitors of α-glucosidase from flowers of Punica granatum L.
Inhibitory effect of a novel combination of Salvia hispanica (chia) seed and Punica granatum (pomegranate) fruit extracts on melanin production.
Preventive Effect of Three Pomegranate (Punica granatum L.) Seeds Fractions on Cerulein-Induced Acute Pancreatitis in Mice.
Potent health effects of pomegranate.
Valorization of pomegranate peel from 12 cultivars: dietary fibre composition, antioxidant capacity and functional properties.
Spectroscopic investigations, antimicrobial, and cytotoxic activity of green synthesized gold nanoparticles.
Administration of a novel plant extract product via drinking water to post-weaning piglets: effects on performance and gut health.
Ethnobotanical and antimicrobial study of some selected medicinal plants used in Khyber Pakhtunkhwa (KPK) as a potential source to cure infectious diseases.
Effect of Punica granatum (pomegranate) juice extract on healthy liver and hepatotoxicity induced by diethylnitrosamine and phenobarbital in male rats.
Attenuating effect of standardized fruit extract of Punica granatum L in rat model of tibial and sural nerve transection induced neuropathic pain.
Effects of rhaponticum carthamoides versus glycyrrhiza glabra and punica granatum extracts on metabolic syndrome signs in rats.
Mucoadhesive polyethylenimine-dextran sulfate nanoparticles containing Punica granatum peel extract as a novel sustained-release antimicrobial.
A preliminary investigation of anticholinesterase activity of some Iranian medicinal plants commonly used in traditional medicine.
Inhibition of melanin content by Punicalagins in the super fruit pomegranate (Punica granatum).
Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin.
Antimicrobial and free radical scavenging activities of five Palestinian medicinal plants.
Wound healing activity of the fruit skin of Punica granatum.
HPLC Evaluation of Phenolic Profile, Nutritive Content, and Antioxidant Capacity of Extracts Obtained from Punica granatum Fruit Peel.
Therapeutic potential of biodegradable microparticles containing Punica granatum L. (pomegranate) in murine model of asthma.
Cytotoxicity of Brazilian plant extracts against oral microorganisms of interest to dentistry.
Protective Effect of Punica granatum L. against Serum/Glucose Deprivation-Induced PC12 Cells Injury.
Antispasmodic Effects of Aqueous and Hydroalcoholic Punica granatum Flower Extracts on the Uterus of Non-pregnant Rats.
The anti-biofilm potential of pomegranate (Punica granatum L.) extract against human bacterial and fungal pathogens.
A Review on Antihyperglycemic and Antihepatoprotective Activity of Eco-Friendly Punica granatum Peel Waste.
Topical anti-inflammatory potential of standardized pomegranate rind extract and ellagic acid in contact dermatitis.
Specific phenolic compounds and sensory properties of a new dealcoholized red wine with pomegranate (Punica granatum L.) extract.
Topical anti-inflammatory and analgesic activities of standardized pomegranate rind extract in comparison with its marker compound ellagic acid in vivo.
Pomegranate and type 2 diabetes.
Anti-coccidial, anthelmintic and antioxidant activities of pomegranate (Punica granatum) peel extract.
The efficacy of Punica granatum extract in the management of recurrent aphthous stomatitis.
Anti-proliferative activity and protection against oxidative DNA damage by punicalagin isolated from pomegranate husk.
Spontaneous ultra fast synthesis of gold nanoparticles using Punica granatum for cancer targeted drug delivery.
Efficacy of Punica granatum L. hydroalcoholic extract on properties of dyed hair exposed to UVA radiation.
Assessment of antioxidant, anti-inflammatory, anti-cholinesterase and cytotoxic activities of pomegranate (Punica granatum) leaves.
Pomegranate (Punica granatum) peel extract provides protection against mercuric chloride-induced oxidative stress in Wistar strain rats.
Studies on the Cytotoxic Activities of Punica granatum L. var. spinosa (Apple Punice) Extract on Prostate Cell Line by Induction of Apoptosis.
Improved glycemic control, pancreas protective and hepatoprotective effect by traditional poly-herbal formulation "Qurs Tabasheer" in streptozotocin induced diabetic rats.
A comparative study on the inhibitory effects of different parts and chemical constituents of pomegranate on α-amylase and α-glucosidase.
Biogenic robust synthesis of silver nanoparticles using Punica granatum peel and its application as a green catalyst for the reduction of an anthropogenic pollutant 4-nitrophenol.
Validated HPLC method for the simultaneous determination of taxol and ellagic acid in a Punica granatum fruit extract containing combination formulation.
Pomegranate (Punica granatum) peel extract efficacy as a dietary antioxidant against azoxymethane-induced colon cancer in rat.
Study of the in vitro antiplasmodial, antileishmanial and antitrypanosomal activities of medicinal plants from Saudi Arabia.
Posterior hyaloid detachment and internal limiting membrane peeling assisted by anthocyanins from acai fruit (Euterpe oleracea) and 10 other natural vital dyes: experimental study in cadaveric eyes.
Pomegranate pericarp extract enhances the antibacterial activity of ciprofloxacin against extended-spectrum β-lactamase (ESBL) and metallo-β-lactamase (MBL) producing Gram-negative bacilli.
In vitro and in vivo evaluation of antioxidant and antigenotoxic potential of Punica granatum leaf extract.
Evaluating the potential role of pomegranate peel in aluminum-induced oxidative stress and histopathological alterations in brain of female rats.
Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation.
Aldose reductase inhibitory activity and antioxidant capacity of pomegranate extracts.
A preliminary investigation of the jack-bean urease inhibition by randomly selected traditionally used herbal medicine.
The Effect of Commiphora molmol (Myrrh) in Treatment of Trichomoniasis vaginalis infection.
Anti-inflammatory effects of pomegranate (Punica granatum L.) husk ellagitannins in Caco-2 cells, an in vitro model of human intestine.
Inhibition of melanin production by a combination of Siberian larch and pomegranate fruit extracts.
Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats.
Seed extract of Punica granatum possesses antioxidant and antiulcer potential.
Partial identification of antifungal compounds from Punica granatum peel extracts.
Antidiabetic and antihyperlipidemic effects of ethanolic extract of leaves of Punica granatum in alloxan-induced non-insulin-dependent diabetes mellitus albino rats.
Ethnobotanical survey and antibacterial activity of plants used in the Altiplane region of Mexico for the treatment of oral cavity infections.
Increased antioxidant content in juice enriched with dried extract of pomegranate (Punica granatum) peel.
Comparative study of the anti-inflammatory and antinociceptive effects of two varieties of Punica granatum.
Anti-urolithiatic effects of Punica granatum in male rats.
Pomegranate fruit extract inhibits UVB-induced inflammation and proliferation by modulating NF-κB and MAPK signaling pathways in mouse skin.
Pharmacological investigations of Punica granatum in glycerol-induced acute renal failure in rats.
Antibacterial and antifungal activities of punica granatum peel extracts against oral pathogens.
Inhibitory effect of pomegranate on intestinal sodium dependent glucose uptake.
The antioxidant potency of Punica granatum L. Fruit peel reduces cell proliferation and induces apoptosis on breast cancer.
Total phenolic distribution of juice, peel, and seed extracts of four pomegranate cultivars.
Comparative Antioxidant Activity and Total Flavonoid Content of Persian Pomegranate (Punica granatum L.) Cultivars.
Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice.
Hydroalcoholic extract based-ointment from Punica granatum L. peels with enhanced in vivo healing potential on dermal wounds.
Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate.
Cardioprotective effect of whole fruit extract of pomegranate on doxorubicin-induced toxicity in rat.
An aqueous pomegranate peel extract inhibits neutrophil myeloperoxidase in vitro and attenuates lung inflammation in mice.
Antimicrobial potential of some plant extracts against Candida species.
Oral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
Antifungal efficacy of Punica granatum, Acacia nilotica, Cuminum cyminum and Foeniculum vulgare on Candida albicans: an in vitro study.
Wound healing activity of Malva sylvestris and Punica granatum in alloxan-induced diabetic rats.
Protective effects of Punica granatum in experimentally-induced gastric ulcers.
Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro.
Broad spectrum antimutagenic activity of antioxidant active fraction of punica granatum L. peel extracts.
In vitro antifungal activity of indirubin isolated from a South Indian ethnomedicinal plant Wrightia tinctoria R. Br.
Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria.
Use of asiatic pennywort Centella asiatica aqueous extract as a bath treatment to control columnaris in Nile tilapia.
Potent antifungal activity of extracts and pure compound isolated from pomegranate peels and synergism with fluconazole against Candida albicans.
Efficacy of Punica granatum extract on in-vitro and in-vivo control of Trichomonas vaginalis.
Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation.
Antibacterial Activity of Medicinal Plants Against Pathogens causing Complicated Urinary Tract Infections.
Effect of traditional Korean medicinal (TKM) triherbal extract on the innate immune system and disease resistance in Paralichthys olivaceus against Uronema marinum.
Cancer chemoprevention by pomegranate: laboratory and clinical evidence.
Antimutagenicity of some flowers grown in Thailand.
Cardioprotective potential of Punica granatum extract in isoproterenol-induced myocardial infarction in Wistar rats.
Effect of pomegranate juice on Angiotensin II-induced hypertension in diabetic Wistar rats.
The effects of pomegranate seed extract and beta-sitosterol on rat uterine contractions.
In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella.
Antimicrobial activity of pomegranate (Punica granatum L.) fruit peels.
Pomegranate (Punica granatum) purified polyphenol extract inhibits influenza virus and has a synergistic effect with oseltamivir.
Antiplasmodial activity of Punica granatum L. fruit rind.
Punica granatum peel extract protects against ionizing radiation-induced enteritis and leukocyte apoptosis in rats.
Effects of pomegranate juice and extract polyphenols on platelet function.
Embryo protective effect of pomegranate (Punica granatum L.) fruit extract in adriamycin-induced oxidative stress.
Exploring the ameliorative potential of Punica granatum in dextran sulfate sodium induced ulcerative colitis in mice.
Pomegranate fruit components modulate human thrombin.
Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin.
International multidimensional authenticity specification (IMAS) algorithm for detection of commercial pomegranate juice adulteration.
Central nervous system activity of acute administration of ethanol extract of Punica granatum L. seeds in mice.
Pomegranate extract mouth rinsing effects on saliva measures relevant to gingivitis risk.
Antimicrobial activities of pomegranate rind extracts: enhancement by addition of metal salts and vitamin C.
Medicinal flowers. XXIII. New taraxastane-type triterpene, punicanolic acid, with tumor necrosis factor-alpha inhibitory activity from the flowers of Punica granatum.
Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes.
Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice.
Protective effects of standardized pomegranate (Punica granatum L.) polyphenolic extract in ultraviolet-irradiated human skin fibroblasts.
Medicinal values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiaca with respect to alterations in tissue lipid peroxidation and serum concentration of glucose, insulin, and thyroid hormones.
Safety assessment of pomegranate fruit extract: acute and subchronic toxicity studies.
Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro.
Antibacterial activity of some medicinal plant extracts.
Protective effects of Punica granatum seeds extract against aging and scopolamine induced cognitive impairments in mice.
Assessment of the genotoxic risk of Punica granatum L. (Punicaceae) whole fruit extracts.
Antibacterial activity directed isolation of compounds from Punica granatum.
Pomegranate peel extract prevents liver fibrosis in biliary-obstructed rats.
Preparative separation of punicalagin from pomegranate husk by high-speed countercurrent chromatography.
Inhibition of UVB-mediated oxidative stress and markers of photoaging in immortalized HaCaT keratinocytes by pomegranate polyphenol extract POMx.
Antibacterial properties of traditionally used Indian medicinal plants.
Cytoprotective effect of preparations from various parts of Punica granatum L. fruits in oxidatively injured mammalian cells in comparison with their antioxidant capacity in cell free systems.
Punica granatum (pomegranate) extract is active against dental plaque.
A new method of standartization of health-promoting pomegranate fruit (Punica granatum) extract.
Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers.
Medicinal plant extracts as anti-Escherichia coli O157:H7 agents and their effects on bacterial cell aggregation.
Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India.
Constituents of the flowers of Punica granatum.
Suppressive effect of Punica granatum on the production of tumor necrosis factor (Tnf) in BV2 microglial cells.
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans.
Antibacterial activities of medicinal plants used for the treatment of diarrhoea in Limpopo Province, South Africa.
Prostate cancer prevention through pomegranate fruit.
Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells.
Punica granatum (pomegranate) flower extract possesses potent antioxidant activity and abrogates Fe-NTA induced hepatotoxicity in mice.
CYP3A4 and CYP2D6 inhibitory activities of Indonesian medicinal plants.
Pomegranate flower extract diminishes cardiac fibrosis in Zucker diabetic fatty rats: modulation of cardiac endothelin-1 and nuclear factor-kappaB pathways.
Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells.
Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer.
Synergic interaction between pomegranate extract and antibiotics against Staphylococcus aureus.
Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro.
Anti-diabetic action of Punica granatum flower extract: activation of PPAR-gamma and identification of an active component.
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice.
Punica granatum flower extract, a potent alpha-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats.
Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids.
Effect of certain bioactive plant extracts on clinical isolates of beta-lactamase producing methicillin resistant Staphylococcus aureus.
Flavonoids from Punica granatum--potential antiperoxidative agents.
Pomegranate extract inhibits Staphylococcus aureus growth and subsequent enterotoxin production.
Possible synergistic prostate cancer suppression by anatomically discrete pomegranate fractions.
Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign.
Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice.
Study on wound healing activity of Punica granatum peel.
Effective medicinal plants against enterohaemorrhagic Escherichia coli O157:H7.
Differentiation-promoting activity of pomegranate (Punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells.
Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry.
Studies on the toxicity of Punica granatum L. (Punicaceae) whole fruit extracts.
Assessment of the effect of Punica granatum (pomegranata) on the bioavailability of the radiopharmaceutical sodium pertechnetate (99mTc) in Wistar rats.
Use of Punica granatum as an antifungal agent against candidosis associated with denture stomatitis.
Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models.
Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer.
Water relationships in Phyllantus orbicularis and Punica granatum antiviral extracts and their influence on stability after freezing and freeze-drying.
Monoacylglycerol from Punica granatum seed oil.
Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin.
Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extracts using in vitro models.
Studies on the hypoglycaemic activity of Punica granatum seed in streptozotocin induced diabetic rats.
Antibacterial activity of Punica granatum.
Molluscicidal activity of Punica granatum bark and Canna indica root.
Effect of Punica granatum Linn. (flowers) on blood glucose level in normal and alloxan-induced diabetic rats.
Studies on antidiarrhoeal activity of Punica granatum seed extract in rats.
Effects of aqueous extracts from Quercus ilex L. root bark, Punica granatum L. fruit peel and Artemisia herba-alba Asso leaves on ethanol-induced gastric damage in rats.
The larvicidal activity of solvent extracts of three medicinal plants against third instar larvae of Chrysomyia albiceps.
Allergy to pomegranate (Punica granatum).
[Growth inhibition of Entamoeba histolytica and E. invadens produced by pomegranate root (Punica granatum L.)].
Anti-implantation activity of some indigenous plants in rats.
[Punica granatum bark extract as a therapeutic agent in tapeworm infection].

Other Information

Export Tariff Code:	1302.19.0000
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PhysChem Properties

Material listed in food chemical codex

Organoleptic Properties

Odor Type: Fruity
pomegranate
General comment	At 100.00 %. pomegranate
Flavor Type: Fruity
pomegranate
General comment	Pomegranate

Occurrences

Potential Uses

Applications	cosmetic flavor and fragrance agents antioxidants
Flavoring purposes	Tonic
Other purposes	Astringents
Cosmetic purposes	Astringents , Fragrance , Tonic

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents, antioxidants
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Safety references

ClinicalTrials.gov:search

AIDS Citations:Search

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EPA ACToR:Toxicology Data

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National Institute of Allergy and Infectious Diseases:Data

punica granatum l. extract

Chemidplus:0084961579