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liver extract

Liver extract is a meaty-flavored substance obtained from mammalian liver, utilized mainly as a cosmetic ingredient for skin conditioning.

General Material Description

Liver extract is a complex composition derived by extracting components from the liver tissue of mammals. This extract typically presents as a powder or concentrate, characterized by a distinctive meaty flavor note reminiscent of liver. Synonyms include desiccated liver extract, liver concentrate powder, and animal extracts, liver. It is classified under the CAS number 8002-47-9 and can be referenced via chemical databases such as PubChem. The extraction process isolates constituents responsible for the characteristic organoleptic properties. Liver extract is sourced mainly from mammalian livers through dehydration or concentration techniques, retaining biochemical components relevant for use primarily in cosmetic applications. Its natural origin and sensory quality facilitate its role in formulas aimed at skin conditioning.

Occurrence, Applicability & Potential Uses

Liver extract is naturally present in mammalian liver tissue and is obtained through extraction procedures for commercial use. It serves primarily as a cosmetic ingredient, specifically categorized for skin conditioning purposes. Regulatory frameworks such as REACH (EU) include liver extract in their inventories, ensuring compliance for cosmetic application. Usage guidelines indicate exclusion from flavor or fragrance uses. The biological occurrence in mammalian liver relates to various proteins, enzymes, and nutrients contributing to its functional properties. In cosmetic formulations, liver extract can support skin conditioning functions, likely attributed to its biochemical makeup. Its meaty flavor characteristic is not generally exploited in flavoring but denotes its complex chemical profile.

Physico-Chemical Properties Summary

Liver extract encompasses a variable composition typical of biological extracts derived from mammalian liver tissue. It exhibits a characteristic meaty aroma associated with volatile organic compounds present in the liver. The material is generally obtained as a powdered concentrate through dehydration or other extraction methods. Its physico-chemical profile is complex, comprising proteins, peptides, and possibly lipids and micronutrients, which affect solubility and stability within formulations. The absence of classified hazards allows for handling under standard safety precautions. The powder’s organoleptic strength necessitates caution in fragrance or flavor use, where it is typically not recommended. Such properties influence its incorporation in cosmetic products aimed at skin conditioning while maintaining formulation integrity.

FAQ

What is liver extract and what are its main characteristics?
Liver extract is a substance obtained from the liver of mammals through extraction processes, generally resulting in a concentrated powder. It has a distinctive meaty flavor and aroma characteristic of liver tissue. The extract contains various biological molecules, such as proteins and enzymes, that originate naturally from the liver. It is primarily used in cosmetic applications, especially as a skin conditioning agent. Synonyms include desiccated liver extract and liver concentrate powder, with chemical registries listing it under CAS number 8002-47-9.
How and where is liver extract typically used, and how is it sourced?
Liver extract is sourced from mammalian livers by processes that concentrate or dry the tissue extracts to retain specific biochemical components. It is mainly utilized in cosmetics for skin conditioning effects, where its biological composition can support skin health. Regulatory standards like REACH (EU) govern its usage to ensure safety and compliance. The extract is not recommended for use in fragrance or flavor applications due to its strong meaty aroma, which may be undesirable in such products. Its natural origin relates it to biological and nutritional components of animal liver.
What regulations and safety information apply to liver extract in commercial use?
Liver extract is listed under REACH (EU) with the CAS number 8002-47-9 and included in regulatory inventories such as ECHA’s database. Classified hazard evaluations, including those aligned with OSHA regulations, indicate no identified hazards or required precautionary statements. Usage guidelines specify liver extract for cosmetic skin conditioning and recommend against its use in fragrance or flavor applications. Toxicity data remain undetermined for oral, dermal, and inhalation routes, supporting cautious handling but no specific hazard classifications. Safety references from multiple sources provide additional data for regulatory compliance and risk assessment.

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Other Information

Wikipedia:View

General Material Information

Preferred name liver extract
Trivial Name Liver extract
Short Description extract obtained from mammalian liver
CAS Number 8002-47-9
Deleted CAS Number 94349-93-6
ECHA Number 232-309-3
FDA UNII Search
Synonyms
  • desiccated liver extract
  • extract obtained from mammalian liver
  • liver concentrate powder
  • Liver extracts
  • Liver, exts.
  • Extracts, liver
  • Atox
  • Antisympathin
  • Liver, ext. residue
  • Animal extracts, liver
  • Exts., liver
  • Liver, extracts

Suppliers

BOC Sciences

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Flavor Type: Meaty
liver, meaty
General comment Liver

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic ingredient for skin conditioning
Recommendation for liver extract usage levels up to:
not for fragrance use.
Recommendation for liver extract flavor usage levels up to:
not for flavor use.

Safety references

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8002-47-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
Chemidplus:0008002479