cynara scolymus leaf extract

Cynara scolymus leaf extract is a botanical product derived from the leaves of the artichoke plant (Cynara scolymus L., family Compositae). This extract appears as a natural preparation characterized by a green flavor closely associated with the fresh artichoke leaf. The material is known under several synonyms including artichoke leaf extract and biobenefity. It contains bioactive constituents such as cynarin, which contribute to its functional and sensory profile. The extract is sourced from the plant's leaves, typically obtained through solvent extraction methods targeting specific phytochemicals. For detailed chemical information, the PubChem database offers controlled-vocabulary resources under identifier 135312255. Originating from a widely cultivated vegetable, the extract finds utility in various applications owing to its recognizable organoleptic and functional attributes.

Cynara scolymus leaf extract naturally occurs in the leaves of the artichoke plant, which is cultivated extensively for food and botanical use. Its applications include use as a cosmetic agent, primarily for skin conditioning purposes, and as a component in dietary supplements. These supplements often capitalize on the extract's bioactive components linked to traditional uses. Under regulatory frameworks such as REACH (EU), the extract is recognized and registered, ensuring compliance for industrial and consumer use. The extract’s incorporation into cosmetic formulas aims to enhance skin texture and condition, while in dietary supplements it supports nutritional or wellness-related formulations. Its appeal lies in its natural origin and characteristic green flavor that also can influence product sensory profiles.

This leaf extract exhibits physico-chemical properties influenced by its complex mixture of bioactive compounds, including phenolic acids such as cynarin. It presents as a green-flavored botanical extract with solubility characteristics suited to various formulation matrices, including aqueous and semi-aqueous systems. The extract's stability profiles depend on factors such as pH, light exposure, and temperature, which are important considerations during storage and product development. Its organoleptic feature of green artichoke flavor can affect sensory perception when incorporated into cosmetic or dietary products. The molecular complexity of the extract requires careful standardization, commonly achieved by specifying cynarin content (e.g., 5%), thus ensuring consistent quality and functional performance across batches.

	cynara scolymus leaf extract
Pubchem (sid):	135312255

FDA Listing of Food Additive Status:	View
Wikipedia:	View

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 1000 mg/kg Indian Journal of Experimental Biology. Vol. 9, Pg. 91, 1971.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic agents, dietary supplements
Recommendation for cynara scolymus leaf extract usage levels up to:
	not for fragrance use.

Safety references

European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the substantiation of a health claim related to the combination of artichoke leaf dry extract standardised in caffeoylquinic acids, monacolin K in red yeast rice, sugar-cane derived policosanols, OPC from French maritime pine bark, garlic dry extract standardised in allicin, d-a-tocopheryl hydrogen succinate, riboflavin and inositol hexanicotinate in Limicol® and reduction of blood LDL-cholesterol concentrations pursuant to Article 14 of Regulation (EC) No 1924/2006 View page or View pdf

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EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

cynara scolymus leaf extract

Chemidplus:0084012146