valeriana officinalis rhizome extract

General Material Information

Preferred name	valeriana officinalis rhizome extract
Trivial Name	Valeriana
Short Description	extract of the rhizomes of the valerian, valeriana officinalis l., valerianaceae
CAS Number	8057-49-6
FEMA Number	3099
ECHA Number	232-501-7
FDA UNII	Search
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	8057-49-6 ; VALERIAN ROOT, EXTRACT (VALERIANA OFFICINALIS L.)
Synonyms	extract of the rhizomes of the valerian, valeriana officinalis l., valerianaceae valerian fluid extract valerian rhizome extract valerian root extract (so called) valerian spray-dried powder extract valeriana officinalis l. rhizome extract Valeriana Valerian Valerian (Valeriana) Valerianae extractum MeSH ID: D014632

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Literature & References

	valeriana officinalis l. rhizome extract
Pubchem (sid):	135331255

Publications by PubMed
Antioxidant effect and study of bioactive components of Valeriana sisymbriifolia and Nardostachys jatamansii in comparison to Valeriana officinalis.
Isolation of 9-hydroxy-10E,12Z-octadecadienoic acid, an inhibitor of fat accumulation from Valeriana fauriei.
Antidepressant effect of Valeriana wallichii patchouli alcohol chemotype in mice: Behavioural and biochemical evidence.
Valeriana jatamansi partially reverses liver cirrhosis and tissue hyperproliferative response in rat.
Chemical analysis and biological activity of the essential oils of two valerianaceous species from China: Nardostachys chinensis and Valeriana officinalis.
Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker.
Terpenoid content of Valeriana wallichii extracts and antidepressant-like response profiles.
Root colonization by symbiotic arbuscular mycorrhizal fungi increases sesquiterpenic acid concentrations in Valeriana officinalis L.
Transport of a GABAA receptor modulator and its derivatives from Valeriana officinalis L. s. l. across an in vitro cell culture model of the blood-brain barrier.
[Studies on chemical constituents of Valeriana officinalis].
[Study on quality specification of Rhizoma et Radix Valeriana Jatamansi].
Effects of aqueous, methanolic and chloroform extracts of rhizome and aerial parts of Valeriana officinalis L. on naloxone-induced jumping in morphine-dependent mice.
Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation.
Polysomnographic evaluation of the hypnotic effect of Valeriana edulis standardized extract in patients suffering from insomnia.

Other Information

FDA Substances Added to Food (formerly EAFUS):	View
FDA Listing of Food Additive Status:	View
MedlinePlusSupp:	View
Wikipedia:	View

Suppliers

Bristol Botanicals	Changsha Organic Herb
Horner International	Xi'an Greena Biotech

PhysChem Properties

Material listed in food chemical codex

Organoleptic Properties

Odor Type: Fruity
valerian root
General comment	At 100.00 %. valerian root
Flavor Type: Fruity
valerian root
General comment	Valerian root

Occurrences

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mammal (species unspecified) LD50 975 mg/kg Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 403, 1988. oral-mammal (species unspecified) LD50 2250 mg/kg Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 19, Pg. 403, 1988. intraperitoneal-mouse LD50 3300 mg/kg KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED Journal of Pharmaceutical Sciences. Vol. 50, Pg. 240, 1961.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
	average usual ppm	average maximum ppm
baked goods:	-	69.00000
beverages(nonalcoholic):	-	25.00000
beverages(alcoholic):	-	-
breakfast cereal:	-	-
cheese:	-	-
chewing gum:	-	-
condiments / relishes:	-	24.00000
confectionery froastings:	-	-
egg products:	-	-
fats / oils:	-	-
fish products:	-	-
frozen dairy:	-	35.00000
fruit ices:	-	35.00000
gelatins / puddings:	-	-
granulated sugar:	-	-
gravies:	-	-
hard candy:	-	65.00000
imitation dairy:	-	-
instant coffee / tea:	-	-
jams / jellies:	-	-
meat products:	-	-
milk products:	-	-
nut products:	-	-
other grains:	-	-
poultry:	-	-
processed fruits:	-	-
processed vegetables:	-	-
reconstituted vegetables:	-	-
seasonings / flavors:	-	-
snack foods:	-	-
soft candy:	-	-
soups:	-	-
sugar substitutes:	-	-
sweet sauces:	-	-

Safety references

ClinicalTrials.gov:search

Daily Med:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

valeriana officinalis l. rhizome extract

Chemidplus:0008057496