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General Material Information

Trivial Name capsicum oleoresin
Short Description capsicum frutescens oleoresin
CAS Number 8023-77-6
FEMA Number 2234
ECHA Number 288-920-0
FDA UNII UW86K581WY
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 8023-77-6 ; CAPSICUM, OLEORESIN (CAPSICUM SPP.)
Synonyms
  • capsicum decolorized oleoresin
  • capsicum e-z resin flavor natural
  • capsicum frutescens oleoresin
  • capsicum oleoresin 1,000,000 scoville units, natural
  • capsicum oleoresin 2,000,000 scoville units USP, natural
  • capsicum oleoresin 500,000 scoville units, natural
  • cayenne oleoresin
  • clearcap super soluble capsicum
  • oleoresin capsicum
  • oleoresin capsicum 6% HPLC
  • oleoresin capsicum W/S
  • organic capsicum oleoresin
  • Resins, oleo-, capsicum
  • Capsicin
  • Resins, capsicum

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Literature & References

capsicum frutescens oleoresin
Canada Domestic Sub. List:8023-77-6
Pubchem (sid):135334295
Publications by PubMed
Formulation of a functional fat spread stabilised by natural antioxidants and emulsifiers.
Dietary plant extracts modulate gene expression profiles in ileal mucosa of weaned pigs after an Escherichia coli infection.
Dietary essential oils improve the hepatic antioxidative status of broiler chickens.
A mixture of carvacrol, cinnamaldehyde, and capsicum oleoresin improves energy utilization and growth performance of broiler chickens fed maize-based diet.
Immune and production responses of dairy cows to postruminal supplementation with phytonutrients.
Dietary plant extracts improve immune responses and growth efficiency of pigs experimentally infected with porcine reproductive and respiratory syndrome virus.
Dietary plant extracts alleviate diarrhea and alter immune responses of weaned pigs experimentally infected with a pathogenic Escherichia coli.
Dietary supplementation of young broiler chickens with Capsicum and turmeric oleoresins increases resistance to necrotic enteritis.
[On the stability of the irritant dibenz-[b,f]-[1,4]-oxazepine (substance CR)].
Effects of dietary addition of capsicum extract on intake, water consumption, and rumen fermentation of fattening heifers fed a high-concentrate diet.
Anti-inflammatory effects of several plant extracts on porcine alveolar macrophages in vitro.
Changes in carotenoids, ascorbic acids, and quality characteristics by the pickling of paprika (Capsicum annuum l.) cultivated in Korea.
Effects of dietary supplementation with phytonutrients on vaccine-stimulated immunity against infection with Eimeria tenella.
Effects of dietary plant-derived phytonutrients on the genome-wide profiles and coccidiosis resistance in the broiler chickens.
Efficacy of capsicum oleoresin nanocapsules formulation by the modified emulsion-diffusion method.
The effect of vitamin E and plant extract mixture composed of carvacrol, cinnamaldehyde and capsaicin on oxidative stress induced by high PUFA load in young pigs.
Long-chain N-vanillyl-acylamides from Capsicum oleoresin.
High-throughput gene expression analysis of intestinal intraepithelial lymphocytes after oral feeding of carvacrol, cinnamaldehyde, or Capsicum oleoresin.
Dietary protein modifies effect of plant extracts in the intestinal ecosystem of the pig at weaning.
Separation of capsaicin from capsaicinoids by simulated moving bed chromatography.
Use of spray-cooling technology for development of microencapsulated capsicum oleoresin for the growing pig as an alternative to in-feed antibiotics: a study of release using in vitro models.
Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
Effects of butyrate, avilamycin, and a plant extract combination on the intestinal equilibrium of early-weaned pigs.
Effects of spray-dried porcine plasma and plant extracts on intestinal morphology and on leukocyte cell subsets of weaned pigs.
The response of gastrointestinal microbiota to avilamycin, butyrate, and plant extracts in early-weaned pigs.
Influence of diet type on the inclusion of plant origin active substances on morphological and histochemical characteristics of the stomach and jejunum walls in chicken.
Capsicum oleoresin: development of an in-soil repellent for pocket gophers.
Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs.
[Inhibition of oxidation of human blood low density lipoproteins by carotenoids from paprika].
A 13-week subchronic toxicity study of paprika color in F344 rats.
Incorporation of carotenoids from paprika oleoresin into human chylomicrons.
Hypocholesterolaemic effect of the oleoresin of Capsicum annum L. in gerbils (Meriones hurrianae Jerdon).
Supercritical CO(2) and subcritical propane extraction of pungent paprika and quantification of carotenoids, tocopherols, and capsaicinoids.
Paprika (Capsicum annuum) oleoresin extraction with supercritical carbon dioxide.
Capsicum-laden soils decrease contact time by northern pocket gophers.
Unexpected death related to restraint for excited delirium: a retrospective study of deaths in police custody and in the community.
Isocratic non-aqueous reversed-phase high-performance liquid chromatographic separation of capsanthin and capsorubin in red peppers (Capsicum annuum L.), paprika and oleoresin.
Effects of oral chemical irritation on taste.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.90.1000
FDA Listing of Food Additive Status:View
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No
Flash Point TCC Value 93.33 °C TCC
Shelf life 12 months (or longer if stored properly.)
Solubility
vegetable oils Yes
oils Yes
water No

Organoleptic Properties

Odor Type: Spicy
spicy, musty, hay, tobacco, herbal
General comment At 100.00 %. chilis musty hay tobacco herbal

Occurrences

Potential Uses

Applications
Flavoring purposes Tonic
Cosmetic purposes Cleansing agents, Fragrance, Tonic

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 3000 mg/kg
BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toksikologicheskii Vestnik. Vol. (2), Pg. 14, 1995.

intraperitoneal-rat LD50 248 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT
Toksikologicheskii Vestnik. Vol. (2), Pg. 14, 1995.

Dermal Toxicity:
skin-rat LD50 > 2500 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT
Toksikologicheskii Vestnik. Vol. (2), Pg. 14, 1995.

Inhalation Toxicity:
inhalation-rat LC50 > 10000 mg/m3/4H
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toksikologicheskii Vestnik. Vol. (2), Pg. 14, 1995.

Safety in use information

Category:
cosmetic and flavor agents
Recommendation for capsicum oleoresin usage levels up to:
not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3. Update in publication number(s): 25
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: 50.0000085.00000
beverages(nonalcoholic): 920.00000105.00000
beverages(alcoholic): 800.00000900.00000
breakfast cereal: 25.0000050.00000
cheese: --
chewing gum: 450.00000500.00000
condiments / relishes: 250.00000330.00000
confectionery froastings: 20.0000050.00000
egg products: --
fats / oils: 100.00000125.00000
fish products: --
frozen dairy: 25.0000028.00000
fruit ices: --
gelatins / puddings: 18.0000020.00000
granulated sugar: --
gravies: 49.0000050.00000
hard candy: 100.00000150.00000
imitation dairy: 15.0000025.00000
instant coffee / tea: 10.000000.15000
jams / jellies: 15.0000025.00000
meat products: 75.00000145.00000
milk products: 15.0000025.00000
nut products: 50.00000100.00000
other grains: 25.0000040.00000
poultry: --
processed fruits: 15.0000050.00000
processed vegetables: 20.0000025.00000
reconstituted vegetables: --
seasonings / flavors: 100.00000200.00000
snack foods: 50.00000100.00000
soft candy: 100.00000200.00000
soups: 25.0000050.00000
sugar substitutes: --
sweet sauces: 50.0000075.00000

Safety references

European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

ClinicalTrials.gov:search
Daily Med:search
EPA Substance Registry Services (TSCA):8023-77-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
capsicum frutescens oleoresin
Chemidplus:0008023776