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ferula assa-foetida gum

Ferula assa-foetida gum is a natural resin used as a flavoring and perfuming agent with characteristic garlic-like odor and flavor.

General Material Description

Ferula assa-foetida gum, commonly known as asafetida or asafoetida, is a natural resinous exudate obtained from the roots of Ferula species. This substance appears as a gummy or resin-like material with a strong, characteristic odor reminiscent of garlic. Known under various synonyms such as hing, Ferula foetida gum, and resins ferula, it is used primarily for its distinctive sensory profile. The resin's flavor and odor attributes relate to sulfur-containing compounds that produce its characteristic pungency. It is cataloged under PubChem (SID 135309999) and occurs naturally in several Ferula plants. This gum resin is traditionally harvested by cutting the plant roots, allowing the oleo-gum-resin to exude and harden for processing and application in food flavoring and perfumery.

Occurrence, Applicability & Potential Uses

Ferula assa-foetida gum occurs naturally as an oleo-gum-resin from the roots of Ferula species native to Asia and the Middle East. Its distinctive garlic-like aroma and flavor have led to its use as a flavoring agent in culinary practices, particularly for imparting garlic notes without using actual garlic. In addition to food flavoring, it serves as a perfuming agent in fragrances, capitalizing on its strong, sulfurous odor profile. Use levels and safety assessments follow FEMA (US) flavoring substance regulations. These include restrictions on its concentration in specific food products such as condiments and baked goods. Its versatility as a flavor and fragrance component aligns with traditional and modern applications.

Physico-Chemical Properties Summary

Ferula assa-foetida gum is a resinous material that presents as a viscous or semi-solid exudate at ambient temperature. Its physical state depends on processing and storage conditions. The resin contains sulfur-containing compounds responsible for its pungent garlic-like odor and flavor. It is soluble in common solvents used for flavor and fragrance extraction, such as propylene glycol. These properties permit its efficient incorporation in complex formulations. The compound’s volatility and stability influence its use in both aroma and flavor applications, allowing it to impart characteristic sensory notes even at low concentrations. Thermal stability parameters are compatible with typical flavoring usage temperatures.

FAQ

What is ferula assa-foetida gum and how is it characterized?
Ferula assa-foetida gum is a natural oleo-gum-resin derived from the roots of Ferula species. It appears as a resinous, gummy substance with a strong, characteristic odor and flavor similar to garlic. It is known by names such as asafetida, asafoetida, hing, and Devil's Dung. The resin contains sulfurous compounds responsible for its pungent sensory profile and is utilized primarily as a flavoring and fragrance agent.
Where does ferula assa-foetida gum come from and in which applications is it used?
This resin is harvested from the roots of Ferula plants native to regions in Asia and the Middle East. Traditionally obtained by incising the root to collect the exuded gum, it is processed for use as a flavoring agent that imparts garlic-like notes. Its applications extend to perfumery as a perfuming agent. Regulatory standards such as those by FEMA (US) guide its safe use concentration levels in various food and beverage products.
What are the safety and regulatory considerations for using ferula assa-foetida gum?
Ferula assa-foetida gum is considered safe for use as a flavoring and fragrance ingredient when used within prescribed limits. No hazard classifications under OSHA or GHS have been found. FEMA (US) has assessed it as generally recognized as safe (GRAS) for flavor use, with established maximum use levels in food categories like condiments and baked goods. Safety assessments from RIFM support these conclusions, and use follows the IFRA Code of Practice globally. Detailed toxicological data exist in public chemical databases, supporting ongoing evaluation.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

ferula assa-foetida l. gum
Canada Domestic Sub. List:9000-04-8
Pubchem (sid):135309999
Publications by PubMed
Impact of Herbal Medicines like Nigella sativa, Trigonella foenum-graecum, and Ferula asafoetida, on Cytochrome P450 2C11 Gene Expression in Rat Liver.
Antimicrobial activity of selected Iranian medicinal plants against a broad spectrum of pathogenic and drug multiresistant micro-organisms.
The Relaxant Effect of Seed's Essential Oil and Oleo-Gum-Resin of Ferula Assa-Foetida on Isolated Rat's Ileum.
Cytotoxic properties of some medicinal plant extracts from mazandaran, iran.
Oleo gum resin of Ferula assa-foetida L. ameliorates peripheral neuropathy in mice.
Relaxant effects of asafoetida extract and its constituent umbelliprenin on guinea-pig tracheal smooth muscle.
Double edged effect of gum-resin of ferula assa-foetida on lifespan of neurons.
Double edged effect of gum-resin of ferula assa-foetida on lifespan of neurons.
Tertiary combination of freeze-dried urine of Indian breeds of cow with plant products against snail Lymnaea acuminata.
Use of complementary and alternative medicine for children: a parents' perspective.
Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida.
Effects of Cymbopogon citratus and Ferula assa-foetida extracts on glutamate-induced neurotoxicity.
Chemical composition, antioxidant and antimicrobial activities of essential oil obtained from Ferula assa-foetida oleo-gum-resin: effect of collection time.
New claims in folk veterinary medicines from Uttar Pradesh, India.
Ferula asafoetida: Traditional uses and pharmacological activity.
Inhibitory effect of Ferula asafoetida L. (Umbelliferae) on Blastocystis sp. subtype 3 growth in vitro.
Evaluation of the effect of Ferula asafoetida Linn. gum extract on learning and memory in Wistar rats.
Dietary agents in the prevention of alcohol-induced hepatotoxicty: preclinical observations.
Bait formulations of molluscicides and their effects on biochemical changes in the ovotestis of snail Lymnaea acuminata (Mollusca; Gastropoda:Lymnaeidae).
Combination of molluscicides with attractant carbohydrates and amino acids in bait formulation against the snail Lymnaea acuminata.
Biological activity of some plant essential oils against Varroa destructor (Acari: Varroidae), an ectoparasitic mite of Apis mellifera (Hymenoptera: Apidae).
Asimafoetidnol: a new sesquiterpenoid coumarin from the gum resin of Ferula assa-foetida.
Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin)-a review.
Galbanic acid, a cytotoxic sesquiterpene from the gum resin of Ferula asafoetida, blocks protein farnesyltransferase.
Influenza A (H(1)N(1)) Antiviral and Cytotoxic Agents from Ferula assa-foetida.
Kinetics of enzyme inhibition by active molluscicidal agents ferulic acid, umbelliferone, eugenol and limonene in the nervous tissue of snail Lymnaea acuminata.
Development and evaluation of hepatoprotective polyherbal formulation containing some indigenous medicinal plants.
Galbanic acid from Ferula szowitsiana enhanced the antibacterial activity of penicillin G and cephalexin against Staphylococcus aureus.
A new ester isolated from Ferula assa-foetida L.
Molluscicidal activity of Ferula asafoetida, Syzygium aromaticum and Carum carvi and their active components against the snail Lymnaea acuminata.
Larvicidal activity of plant extracts used alone and in combination with known synthetic larvicidal agents against Aedes aegypti.
Antispasmodic and hypotensive effects of Ferula asafoetida gum extract.
Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
Sesquiterpene coumarins from the roots of Ferula assa-foetida.
Reversal of aflatoxin induced liver damage by turmeric and curcumin.

Other Information

FDA Substances Added to Food (formerly EAFUS):View
Export Tariff Code:3301.90.0000
Wikipedia:View

General Material Information

Preferred name ferula assa-foetida gum
Trivial Name Resins, asafetida
Short Description asafetida gum
CAS Number 9000-04-8
FEMA Number 2107
ECHA Number 232-522-1
FDA UNII Search
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 9000-04-8 ; ASAFETIDA, GUM (FERULA ASSAFOETIDA L.)
Synonyms
  • asa foetida
  • asafetida gum
  • asafoetida gum
  • assafetida gum
  • ferula asafoetida gum
  • ferula foetida gum
  • gum asafoetida
  • scorodosma foetidum gum
  • ferula assa-foetida l. gum
  • Resins, asafetida
  • Asafetida
  • Asafoetida
  • Hing
  • Resins, Ferula
  • Asa-foetida resin
  • Asa fetida
  • Chinese Asafoetida
  • Resina Ferulae
  • Asafoetida resin
  • Ferula asafoetida resin
  • Devil's Dung
  • Narthex
  • Resina Ferulaa asafoetidae
  • A wei
  • E wei
  • Awei
  • Ewei

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Odor Type: Garlic
asafetida, garlic
General comment At 0.10 % in propylene glycol. asafetida
Flavor Type: Garlic
asafetida, garlic
General comment Asafetida

Occurrences

Potential Uses

Applications
Flavoring purposes Garlic
Cosmetic purposes Perfuming agents

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -15.00000
beverages(nonalcoholic): -5.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: 3.00000160.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -10.00000
fruit ices: -10.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 15.0000025.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

Daily Med:search
Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):9000-04-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
ferula assa-foetida l. gum
Chemidplus:0009000048