tetradecanal

General Material Information

Preferred name	tetradecanal
Trivial Name	Tetradecanal
Short Description	myristaldehyde
Formula	C14 H28 O
CAS Number	124-25-4
Deleted CAS Number	511542-15-7
FEMA Number	2763
Flavis Number	5.032
ECHA Number	204-692-7
FDA UNII	44AJ2LT15N
Nikkaji Number	J1.509A
Beilstein Number	1765987
MDL	MFCD00007019
COE Number	118
xLogP3-AA	6.00 (est)
Bio Activity Summary	External link
NMR Predictor	External link
JECFA Food Flavoring	112 myristaldehyde
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	124-25-4 ; MYRISTALDEHYDE
Synonyms	aldehyde C-14 myristic aldehyde C-14, myristic myristaldehyde myristic aldehyde myristyl aldehyde 1-tetradecanal N- tetradecanal tetradecyl aldehyde 1-tetradecyl aldehyde tetradecylaldehyde n-Tetradecyl aldehyde Myristylaldehyde n-Tetradecanal Tetradecanaldehyde 1-Tetradecanal Myristinaldehyde NSC 66435 Aldehyde peche (C14) Peach aldehyde (C14)

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

	tetradecanal
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	124-25-4
Pubchem (cid):	31291
Pubchem (sid):	134975060
Flavornet:	124-25-4
Pherobase:	View

Publications by PubMed
Comparison of the volatile oil composition of three Atalantia species.
Human liver tissue metabolic profiling research on hepatitis B virus-related hepatocellular carcinoma.
Essential oils from the leaves of six medicinal plants of Nigeria.
Semi-selective fatty acyl reductases from four heliothine moths influence the specific pheromone composition.
Composition of the essential oil constituents from leaves and stems of Korean Coriandrum sativum and their immunotoxicity activity on the Aedes aegypti L.
Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions.
Stereoselective synthesis of bioactive natural spiroacetals aculeatins A and B.
Gene cloning and characterization of an aldehyde dehydrogenase from long-chain alkane-degrading Geobacillus thermoleovorans B23.
Stingless bees: chemical differences and potential functions in Nannotrigona testaceicornis and Plebeia droryana males and workers.
Stereoselective synthesis of (2S,3S,4Z)-4-fluoro-1,3-dihydroxy-2-(octadecanoylamino)octadec-4-ene, [(Z)-4-fluoroceramide], and its phase behavior at the air/water interface.
Attraction of female Culex quinquefasciatus Say (Diptera: Culicidae) to odors from chicken feces.
Characterisation of recombinant human fatty aldehyde dehydrogenase: implications for Sjögren-Larsson syndrome.
Inter- and intraspecific variation in defensive compounds produced by five neotropical stink bug species (Hemiptera: Pentatomidae).
Support for (Z)-11-hexadecanal as a pheromone antagonist in Ostrinia nubilalis: flight tunnel and single sensillum studies with a New York population.
Dufour's gland secretion as a repellent used during usurpation by the slave-maker ant Rossomyrmex minuchae.
6-Substituted indanoyl isoleucine conjugate induces tobacco plant responses in secondary metabolites.
First identification of a putative sex pheromone in a praying mantid.
Defensive chemistry of an aposematic bug, Pachycoris stallii Uhler and volatile compounds of its host plant Croton californicus Muell.-Arg.
Semiochemicals from the predatory stink bug Eocanthecona furcellata (Wolff): components of metathoracic gland, dorsal abdominal gland, and sternal gland secretions.
Pheromone components of the wheat stem sawfly: identification, electrophysiology, and field bioassay.
Kinetic analysis of bacterial bioluminescence in water-organic media.
(E4,Z9)-tetradecadienal, a sex pheromone for three North American moth species in the genus Saturnia.
Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase.
Long-chain aldehyde dehydrogenase that participates in n-alkane utilization and wax ester synthesis in Acinetobacter sp. strain M-1.
Interaction of Photobacterium leiognathi and Vibrio fischeri Y1 luciferases with fluorescent (antenna) proteins: bioluminescence effects of the aliphatic additive.
Polyketide origin of pheromones of Carpophilus davidsoni and C. mutilatus (Coleoptera: Nitidulidae).
Comparison of the reactivity of tetradecenoic acids, a triacsin, and unsaturated oximes with four purified Saccharomyces cerevisiae fatty acid activation proteins.
Male-produced aggregation pheromone ofCarpophilus mutilatus (Coleoptera: Nitidulidae).
Fatty acid-enhanced binding of flavin mononucleotide to bacterial luciferase measured by steady-state fluorescence.
Long-chain alcohol and aldehyde dehydrogenase activities in Acinetobacter calcoaceticus strain HO1-N.
Mandibular gland secretions of the male beewolvesPhilanthus crabroniformis, P. barbatus, andP. pulcher (Hymenoptera: Sphecidae).
Characterization of N-myristoyl transferase inhibitors and their effect on HIV release.
Electronic excitation transfer in the complex of lumazine protein with bacterial bioluminescence intermediates.
Bioluminescence decay kinetics in the reaction of bacterial luciferase with different aldehydes.
Effect of release rate and ratio of (Z)-11-hexadecen-1-ol from synthetic pheromone blends on trap capture ofHeliothis subflexa (Lepidoptera: Noctuidae).
Growth and luminescence of the bacterium Xenorhabdus luminescens from a human wound.
Bioluminescence spectral and fluorescence dynamics study of the interaction of lumazine protein with the intermediates of bacterial luciferase bioluminescence.
Dynamic fluorescence study of the interaction of lumazine protein with bacterial luciferases.
Elongation of exogenous fatty acids by the bioluminescent bacterium Vibrio harveyi.
Dynamic fluorescence properties of bacterial luciferase intermediates.
Spruce budworm (Choristoneura fumiferana) pheromone chemistry and behavioral responses to pheromone components and analogs.
Chemical and behavioral analyses of volatile sex pheromone components released by callingHeliothis virescens (F.) females (Lepidoptera: Noctuidae).
Vibrio harveyi aldehyde dehydrogenase. Partial reversal of aldehyde oxidation and its possible role in the reduction of fatty acids for the bioluminescence reaction.
Kinetics of bacterial bioluminescence and the fluorescent transient.
Synthesis and antiallergenic properties of 3-n-pentadecyl- and 3-n-heptadecylcatechol esters.
Fatty acid reductase in bioluminescent bacteria. Resolution from aldehyde reductases and characterization of the aldehyde product.
Trace chemicals: the essence of sexual communication systems in heliothis species.
Evidence for tetradecanal as the natural aldehyde in bacterial bioluminescence.
The aldehyde content of luminous bacteria and of an "aldehydeless" dark mutant.

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
CHEBI:	View
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB34283
FooDB:	FDB012621
Export Tariff Code:	2912.19.5000
Typical G.C.
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Suppliers

Aurochemicals	Beijing Lys Chemicals
BOC Sciences	Endeavour Specialty Chemicals
Global Essence	Kun Shan P&A
Penta International	Phoenix Aromas & Essential Oils
R C Treatt & Co Ltd	Robinson Brothers
Santa Cruz Biotechnology	TCI AMERICA
WholeChem	Beijing Lys Chemicals Co, LTD.
Endeavour Specialty Chemicals Ltd	Global Essence Inc.
Penta International Corporation	Robinson Brothers Limited
R C Treatt and Co Ltd	WholeChem, LLC

PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	212.37635803223
Melting Point	20 to 21°C @ 760 mm Hg
Acid Value	15 max KOH/g
Vapor Pressure	0.006 mmHg @ 25 °C
Flash Point TCC Value	110 °C TCC
logP (o/w)	6.008 est
Solubility
alcohol	Yes
dipropylene glycol	Yes
water, 0.4852 mg/L @ 25 °C (est)	Yes
water	No

Organoleptic Properties

Odor Type: Waxy
fatty, waxy, amber, incense, dry, citrus peel, musk, dairy, creamy, fishy, fruity, pear
Odor strength	medium
Substantivity	400 hour(s) at 100.00 %
Luebke, William tgsc, (1987)	At 100.00 %. fatty waxy amber incense dry citrus peel musk
Mosciano, Gerard P&F 22, No. 3, 47, (1997)	Fatty, waxy, dairy, creamy and fishy with a fruity, pear nuance
Flavor Type: Fatty
fatty, lactonic, coconut, woody, fishy, fruity
Mosciano, Gerard P&F 22, No. 3, 47, (1997)	At 10.00 ppm. Fatty, lactonic, coconut, woody and fishy with a fruity nuance

Occurrences

Potential Uses

Applications	flavor and fragrance agents
Odor purposes	Acacia, Amber, Balsam, Blackberry, Citrus, Coconut, Cucumber, Floral, Ginger, Herbal, Honey, Hop, Incense, Kumquat, Lily of the valley, Moss, Musk, Orris, Peanut, Violet, Woody
Flavoring purposes	Dairy, Fat
Other purposes	Waxy
Cosmetic purposes	Perfuming agents

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 36 - Wear suitable protective clothing.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
1 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 11, Pg. 487, 1973.
Dermal Toxicity:
skin-rabbit LD50 > 10000 mg/kg Food and Cosmetics Toxicology. Vol. 11, Pg. 487, 1973.
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for tetradecanal usage levels up to:
	1.0000 % in the fragrance concentrate.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
		average usual ppm	average maximum ppm
baked goods:		0.08000	24.00000
beverages(nonalcoholic):		-	2.70000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		0.06000	8.00000
fruit ices:		0.06000	8.00000
gelatins / puddings:		-	0.15000
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	1.90000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-