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muscomer

Muscomer is a fragrance compound known for its sweet amber, musk, and sandalwood odor profile used primarily in perfumery applications.
Chemical Structure

General Material Description

Muscomer is a bicyclic dimethanol compound with the molecular formula C12H20O2. Known technically as tricyclodecanedimethanol, it appears as a colorless to pale liquid and emits a complex aroma characterized by sweet amber, musk, and sandalwood notes. This fragrance ingredient is a mixture of isomers often referenced under synonymous names including muscomer 1151P and tricyclo(5.2.1.0'2,7)decane-4,8-dimethanol. Its sensory qualities lend a soft, creamy, and floral reinforcement to blends, making it a valued component in perfumery. The compound's sourcing typically involves synthetic organic chemistry routes, and more information is accessible via chemical databases such as PubChem.

Occurrence, Applicability & Potential Uses

Muscomer does not occur naturally but is synthesized for use primarily as a fragrance agent in perfumery. It is recognized for imparting amber, balsam, moss, musk, oriental, and sandalwood nuances. Within fragrance formulations, it provides exceptional soft and creamy musk impressions reinforced by floral and sandalwood notes, making it useful in complex olfactory compositions. Regulatory guidelines under IFRA (Global) establish usage parameters for muscomer as a perfuming agent, thereby ensuring compliance and safe application in cosmetic products. Its solubility in alcohol facilitates formulation in various fragrance delivery systems.

Physico-Chemical Properties Summary

Muscomer displays a molecular weight of approximately 196.29 g/mol and the chemical formula C12H20O2. It possesses a moderate estimated log P of 1.617, indicating balanced lipophilicity, and shows partial solubility in water with increased solubility in alcohol solvents. The compound has a relatively high boiling point range between 349 and 352°C at atmospheric pressure and a flash point around 230°F (approximately 110°C), suggesting reasonable thermal stability for perfumery use. These physicochemical attributes influence its incorporation into formulas, favoring alcohol-based carriers and ensuring fragrance stability and substantivity during product life.

FAQ

What is muscomer and what are its primary characteristics?
Muscomer is a synthetic fragrance compound known chemically as tricyclodecanedimethanol. It is characterized by a sweet amber scent combined with musk and sandalwood notes, providing a soft and creamy aroma with floral reinforcement. This odor profile makes it a suitable ingredient in perfumery where a complex, warm base note is desired.
How is muscomer used and where is it commonly applied?
Muscomer is employed primarily as a fragrance agent in the cosmetic industry, particularly in perfuming products. It enhances fragrance blends by contributing amber, balsam, moss, musk, oriental, and sandalwood tones. Its compatibility with alcohol solvents allows for versatile formulation in various types of fragrance delivery systems.
What safety and regulatory considerations apply to muscomer?
Under the IFRA (Global) standards, muscomer is regulated for use as a fragrance ingredient to ensure consumer safety. No specific hazard classifications are currently noted under GHS or OSHA regulations. Safety data sheets and fragrance material safety assessments are available to guide responsible use. Muscomer is not recommended for flavor use and manufacturers adhere to IFRA guidelines to maintain concentration limits in products.

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2906.19.5000
ChemSpider:View

General Material Information

Preferred name muscomer
Trivial Name Tricyclodecanedimethanol
Short Description muscomer
Formula C12 H20 O2
CAS Number 26896-48-0
ECHA Number 248-096-5
FDA UNII Search
MDL MFCD00151166
xLogP3-AA 1.50 (est)
NMR Predictor External link
Synonyms
  • 4,8-bis( hydroxymethyl) tricyclo(5.2.1.o/ 2,6)decane (mixture of isomers)
  • muscomer 1151 P (Grau)
  • muscomer 1151P (Grau)
  • muscomer 810P (Grau)
  • muscomer extra 810 P (Grau)
  • muscomer S 900P (Grau)
  • octahydro-4,7-methano-1H-indene-5,-dimethanol
  • octahydro-4,7-methano-1H-indenedimethanol
  • tricyclo(5.2.1.0 '2,7)decane-4,8-dimethanol (mixture of isomers)
  • tricyclo(5.2.1.0'2,7)decane-4,8-dimethanol
  • tricyclo(5.2.1.0'2,7)decane-4,8-dimethanol (mixture of isomers)
  • tricyclodecane dimethanol
  • tricyclodecane dimethanol (mixture of isomers)
  • tricyclodecanedimethanol

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 196.28979492188
Boiling Point 349 to 352°C @ 760 mm Hg
Flash Point TCC Value 110 °C TCC
logP (o/w) 1.617 est
Solubility
alcohol Yes
water, 476.4 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Amber
sweet, amber, musk, floral, sandalwood
Odor strength medium
Substantivity 400 hour(s) at 100.00 %
Luebke, William tgsc, (1987) At 100.00 %. sweet amber musk floral sandalwood
An unusual musk that also has aspects of sandalwood and is therefore helpful where both notes are desired. Exceptionally soft and creamy, with good floral reinforcement. Sweet amber musk floral sandalwood

Potential Uses

Applications
Odor purposes Amber , Balsam , Moss , Musk , Oriental , Sandalwood
Cosmetic purposes Perfuming agents

Safety Information

Safety information

Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for muscomer flavor usage levels up to:
not for flavor use.

Safety references

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):26896-48-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :160138
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
tricyclodecanedimethanol
Chemidplus:0026896480