2-acetyl-3,5(or 6)-dimethyl pyrazine

General Material Information

Preferred name	2-acetyl-3,5(or 6)-dimethyl pyrazine
Trivial Name	1-(3,?-Dimethyl-2-pyrazinyl)ethanone
Short Description	2-acetyl-3,(5 or 6)-dimethylpyrazine
Formula	C8 H10 N2 O
CAS Number	72797-17-2
FEMA Number	3327
ECHA Number	276-848-2
FDA UNII	O16657H2TP
MDL	MFCD00055023
COE Number	11294
xLogP3-AA	0.60 (est)
NMR Predictor	External link
JECFA Food Flavoring	786 2-acetyl-3,(5 or 6)-dimethylpyrazine
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	977043-63-2 ; 2-ACETYL-3, 5(OR 6)-DIMETHYLPYRAZINE, MIXTURE OF ISOMERS
Synonyms	2 acetyl-3, 5 (or 6) dimethylpyrazine 2-acetyl-3, 5 (or 6) dimethylpyrazine 2-acetyl-3,(5 or 6)-dimethylpyrazine 2-acetyl-3,5(6)-dimethyl pyrazine 2-acetyl-3,5(6)-dimethylpyrazine 2-acetyl-3,5(or 6)-dimethylpyrazine 2-acetyl-3,5-dimethyl pyrazine and 2-acetyl-3,6-dimethyl pyrazine mixture 2-acetyl-3,5-dimethylpyrazine and 2-acetyl-3,6-dimethylpyrazine mixture 2-acetyl-3,6-dimethylpyrazine and 2-acetyl-3,5-dimethylpyrazine mixture 1-(3,5(or 6)- dimethyl pyrazinyl) ethan-1-one 1-(3,?- dimethyl pyrazinyl) ethan-1-one 1-(3,5(or 6)- dimethyl pyrazinyl) ethanone 1-(3,5-dimethylpyrazin-1-ium-1-yl)ethanone 1-(3,5(or 6)- dimethylpyrazinyl)ethan-1-one 1-(3,?- dimethylpyrazinyl)ethan-1-one 1-(3,5(or 6)- dimethylpyrazinyl)ethanone ethanone, 1-(3,?-dimethyl-2-pyrazinyl)- ethanone, 1-(3,?-dimethylpyrazinyl)- 1-(3,5-dimethylpyrazin-1-ium-1-yl)ethanone 1-(3,?-Dimethyl-2-pyrazinyl)ethanone

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	HMDB39998
FooDB:	FDB008893
Export Tariff Code:	2933.90
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Ambles Nature et Chimie	BOC Sciences
Diffusions Aromatiques	Indukern F&F
Jiangyin Healthway	Kingchem Laboratories
Parchem	Pearlchem Corporation
R C Treatt & Co Ltd	Synerzine
United International	Indukern, S.A. F&F Ingredients Division
Jiangyin Healthway International Trade Co., Ltd	Synerzine, Inc.
R C Treatt and Co Ltd	Qingdao Free Trade Zone United International Co Ltd

Material listed in food chemical codex	No
Molecular weight	150.18089294434
Specific gravity	@ 25 °C
Pounds per Gallon
Specific gravity	@ 25 °C
Pounds per Gallon	8.903 to 8.945
Vapor Pressure	3 mmHg @ 20 °C
Flash Point TCC Value	90.56 °C TCC
logP (o/w)	1.08
Solubility
alcohol	Yes
water, 1.855e+004 mg/L @ 25 °C (est)	Yes
water	No

Odor Type: Nutty
nutty, hazelnut roasted hazelnut, peanut roasted peanut, popcorn, corn chip, grain toasted grain, nut flesh, peanut butter
Odor strength	high , recommend smelling in a 0.10 % solution or less
Substantivity	21 hour(s) at 100.00 %
Luebke, William tgsc, (2017)	At 0.10 % in dipropylene glycol. nutty roasted hazelnut roasted peanut popcorn corn chip toasted grain nut flesh peanut butter
Flavor Type: Nutty
nutty, hazelnut roasted hazelnut, peanut roasted peanut, grain toasted grain, nut flesh, peanut butter
Luebke, William tgsc, (2017)	Nutty roasted hazelnut roasted peanut popcorn toasted grain nut flesh peanut butter

Applications	flavor and fragrance agents
Odor purposes	Butterscotch, Chocolate, Coffee, Hazelnut, Popcorn, Toffee
Flavoring purposes	Caramel, Nut roasted nut

European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-acetyl-3,5(or 6)-dimethyl pyrazine usage levels up to:
	0.1000 % in the fragrance concentrate.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 6
Click here to view publication 6
		average usual ppm	average maximum ppm
baked goods:		-	5.00000
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	5.00000
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	1.00000
fruit ices:		-	1.00000
gelatins / puddings:		-	1.00000
granulated sugar:		-	-
gravies:		-	5.00000
hard candy:		-	5.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	1.00000
meat products:		-	5.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	5.00000
sugar substitutes:		-	-
sweet sauces:		-	-

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):72797-17-2

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :3085845

National Institute of Allergy and Infectious Diseases:Data

1-(3,5-dimethylpyrazin-1-ium-1-yl)ethanone

Chemidplus:0072797172