Preferred name | benzaldehyde |
Trivial Name | Benzaldehyde |
Short Description | artificial bitter almond oil |
Formula | C7 H6 O |
CAS Number | 100-52-7 |
FEMA Number | 2127 |
Flavis Number | 5.013 |
ECHA Number | 202-860-4 |
FDA UNII | TA269SD04T |
Nikkaji Number | J4.010J |
Beilstein Number | 0471223 |
MDL | MFCD00003299 |
COE Number | 101 |
Bio Activity Summary | External link |
NMR Predictor | External link |
JECFA Food Flavoring | 22 benzaldehyde |
FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
FDA Mainterm | 100-52-7 ; BENZALDEHYDE |
Synonyms |
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Perfumer & Flavorists | Start search |
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NCBI | Start search |
benzaldehyde | |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 100-52-7 |
Pubchem (cid): | 240 |
Pubchem (sid): | 134972707 |
Flavornet: | 100-52-7 |
Pherobase: | View |
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
FDA Substances Added to Food (formerly EAFUS): | View |
FDA Indirect Additives used in Food Contact Substances: | View |
CHEBI: | View |
CHEMBL: | View |
UM BBD: | Search |
KEGG (GenomeNet): | C00261 |
HMDB (The Human Metabolome Database): | HMDB06115 |
FooDB: | FDB014661 |
YMDB (Yeast Metabolome Database): | YMDB01326 |
Export Tariff Code: | 2912.21.0000 |
Typical G.C. | |
VCF-Online: | VCF Volatile Compounds in Food |
ChemSpider: | View |
Wikipedia: | View |
Formulations/Preparations: •benzaldehyde is commercially available in two grades. pure benzaldehyde, which is suitable for most uses, accounts for more than 95% of the amount sold. double-distilled benzaldehyde is used mainly in the pharmaceutical, perfume, and flavor industries . •cmpd benzaldehyde elixir nf. dissolve benzaldehyde (0.5 ml) & vanillin (1 g) in alcohol syrup orange flower water and purified water . •benzaldehyde fcc grade of benzaldehyde free from chlorine. •grades: technical; nf |
Material listed in food chemical codex | Yes |
Molecular weight | 106.1240234375 |
Specific gravity | @ 25 °C |
Pounds per Gallon | 8.662 to 8.704 |
Specific gravity | @ 15 °C |
Pounds per Gallon | 8.747 to 8.797 |
Refractive Index | 1.544 to 1.546 @ 20 °C |
Melting Point | -26 to -25°C @ 760 mm Hg |
Boiling Point | 62 to 63°C @ 10 mm Hg |
Boiling Point | 178 to 179°C @ 760 mm Hg |
Acid Value | 5 max KOH/g |
Vapor Pressure | 1.27 mmHg @ 25 °C |
Vapor Density | 3.7 |
Flash Point TCC Value | 62.78 °C TCC |
logP (o/w) | 1.48 |
Shelf life | 18 months (or longer if stored properly.) |
Storage notes | Store in cool, dry place in tightly sealed containers, protected from heat and light. store under nitrogen. |
Solubility | |
ether | Yes |
ethyl alcohol, 1:1-1::1.5 in 70% alcohol | Yes |
ethyl alcohol, 1:2.5 in 60% alcohol | Yes |
ethyl alcohol, 1:8 in 50% alcohol | Yes |
ethyl alcohol, 5 vol. of 50% alcohol | Yes |
kerosene | Yes |
paraffin oil | Yes |
water, 6570 mg/L @ 25 °C (exp) | Yes |
Stability | |
non-discoloring in most media | Unspecified |
Odor Type: Fruity | |
sharp, sweet, bitter, almond, cherry, fruity, powdery, nutty, cherry maraschino cherry | |
Odor strength | high , recommend smelling in a 10.00 % solution or less |
Substantivity | 4 hour(s) at 100.00 % |
Luebke, William tgsc, (1982) | At 10.00 % in dipropylene glycol. strong sharp sweet bitter almond cherry |
Mosciano, Gerard P&F 19, No. 5, 79, (1994) | Almond, fruity, powdery, nutty and benzaldehyde-like |
Flavor Type: Fruity | |
fruity, cherry, cherry maraschino cherry, oily, nutty, woody, fruit tropical fruit, sweet, almond | |
Luebke, William tgsc, (1982) | Fruity cherry maraschino cherry oily nutty woody tropical fruit |
Mosciano, Gerard P&F 19, No. 5, 79, (1994) | At 50.00 ppm. Sweet, oily, almond, cherry, nutty and woody |
Useful in: brown caramel, brown nuts, brown cocoa, brown coffee, brown others, dairy, fruity red, fruity yellow, fruity tropical, fruity others, sweet others, alcoholics. | Bitter almond-like |
General comment | Almond, sweet and spicy |
(data available) |
Preferred SDS: View | |
European information : | |
Most important hazard(s): | |
Xn - Harmful. | |
R 22 - Harmful if swallowed. S 02 - Keep out of the reach of children. S 24 - Avoid contact with skin. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. | |
Hazards identification | |
Classification of the substance or mixture | |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
Flammable liquids (Category 4), H227 Acute toxicity, Oral (Category 4), H302; Acute toxicity, Inhalation (Category 4), H332 Skin irritation (Category 2), H315 Skin sensitisation (Category 1), H317 Respiratory sensitisation (Category 1), H334 Acute aquatic toxicity (Category 2), H401 | |
GHS Label elements, including precautionary statements | |
Pictogram | ![]() |
Signal word | Warning |
Hazard statement(s) | |
H227 - Combustible liquid H302 + H332 - Harmful if swallowed or if inhaled H315 - Causes skin irritation H317 - May cause an allergic skin reaction H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled H401 - Toxic to aquatic life | |
Precautionary statement(s) | |
P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P272 - Contaminated work clothing should not be allowed out of the workplace. P273 - Avoid release to the environment. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P285 - In case of inadequate ventilation wear respiratory protection. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302 + P352 - IF ON SKIN: wash with plenty of soap and water. P304 + P341 - IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P330 - Rinse mouth. P333 + P313 - IF SKIN irritation or rash occurs: Get medical advice/attention. P342 + P311 - IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. P362 - Take off contaminated clothing and wash before reuse. P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction. P403 + P235 - Store in a well-ventilated place. Keep cool. P501 - Dispose of contents/ container to an approved waste disposal plant. | |
Oral/Parenteral Toxicity: | |
gavage-guinea pig LD50 [sex: M,F] 1000 mg/kg (Jenner et al., 1964) gavage-rat LD50 [sex: M,F] 1300 mg/kg (Jenner et al., 1964) oral-rat LD50 2850 mg/kg (Sporn et al., 1967) gavage-rat LD50 [sex: M,F] 1300 mg/kg (Taylor et al., 1964) oral-guinea pig LD50 1000 mg/kg KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE BEHAVIORAL: TREMOR Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964. oral-mammal (species unspecified) LD50 2020 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974. oral-rat LD50 1300 mg/kg BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964. oral-mouse LD50 28 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 99, 1976. intraperitoneal-mouse LD50 9 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: TREMOR European Journal of Toxicology and Environmental Hygiene. Vol. 9, Pg. 99, 1976. | |
Dermal Toxicity: | |
subcutaneous-rat LD50 5000 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Archives Internationales de Pharmacodynamie et de Therapie. Vol. 27, Pg. 163, 1922. subcutaneous-rabbit LD50 5000 mg/kg Food and Cosmetics Toxicology. Vol. 14, Pg. 693, 1976. | |
Inhalation Toxicity: | |
inhalation-mouse LC > 500 mg/m3 SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(11), Pg. 40, 1974. inhalation-rat LC > 500 mg/m3 LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(11), Pg. 40, 1974. |
Category: | |||
flavor and fragrance agents | |||
RIFM Fragrance Material Safety Assessment: Search | |||
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
IFRA Critical Effect: | |||
Dermal sensitization and systemic toxicity | |||
View the IFRA Standard | |||
View IFRA Standards Library for complete information. | |||
Please review Amendment 49 IFRA documentation for complete information. | |||
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): | |||
Category 1: Products applied to the lips | |||
0.045 % | |||
Category 2: Products applied to the axillae | |||
0.014 % | |||
Category 3: Products applied to the face/body using fingertips | |||
0.27 % | |||
Category 4: Products related to fine fragrance | |||
0.25 % | |||
Category 5: Products applied to the face and body using the hands (palms), primarily leave-on | |||
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on | |||
0.064 % | |||
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on | |||
0.064 % | |||
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on | |||
0.064 % | |||
Category 5D: Baby Creams, baby Oils and baby talc | |||
0.021 % | |||
Category 6: Products with oral and lip exposure | |||
0.15 % | |||
Category 7: Products applied to the hair with some hand contact | |||
Category 7A: Rinse-off products applied to the hair with some hand contact | |||
0.52 % | |||
Category 7B: Leave-on products applied to the hair with some hand contact | |||
0.52 % | |||
Category 8: Products with significant anogenital exposure | |||
0.021 % | |||
Category 9: Products with body and hand exposure, primarily rinse off | |||
0.49 % | |||
Category 10: Household care products with mostly hand contact | |||
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) | |||
0.49 % | |||
Category 10B: Household aerosol/spray products | |||
1.80 % | |||
Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate | |||
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure | |||
0.021 % | |||
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure | |||
0.021 % | |||
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin | |||
No Restriction | |||
Notes: | |||
IFRA FLAVOR REQUIREMENTS: | |||
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. | |||
Maximised Survey-derived Daily Intakes (MSDI-EU): | 7900.00 (μg/capita/day) | ||
Maximised Survey-derived Daily Intakes (MSDI-USA): | 36000.00 (μg/capita/day) | ||
Structure Class: | I | ||
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
publication number: 3 | |||
Click here to view publication 3 | |||
average usual ppm | average maximum ppm | ||
baked goods: | - | 110.00000 | |
beverages(nonalcoholic): | - | 36.00000 | |
beverages(alcoholic): | 50.00000 | 60.00000 | |
breakfast cereal: | - | - | |
cheese: | - | - | |
chewing gum: | - | 840.00000 | |
condiments / relishes: | - | - | |
confectionery froastings: | - | - | |
egg products: | - | - | |
fats / oils: | - | - | |
fish products: | - | - | |
frozen dairy: | - | 42.00000 | |
fruit ices: | - | 42.00000 | |
gelatins / puddings: | - | 160.00000 | |
granulated sugar: | - | - | |
gravies: | - | - | |
hard candy: | - | 120.00000 | |
imitation dairy: | - | - | |
instant coffee / tea: | - | - | |
jams / jellies: | - | - | |
meat products: | - | - | |
milk products: | - | - | |
nut products: | - | - | |
other grains: | - | - | |
poultry: | - | - | |
processed fruits: | - | - | |
processed vegetables: | - | - | |
reconstituted vegetables: | - | - | |
seasonings / flavors: | - | - | |
snack foods: | - | - | |
soft candy: | - | - | |
soups: | - | - | |
sugar substitutes: | - | - | |
sweet sauces: | - | - |
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23 View page or View pdf |
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf |
EPI System: View |
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Daily Med:search |
NIOSH International Chemical Safety Cards:search |
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AIDS Citations:Search |
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EPA Substance Registry Services (TSCA):100-52-7 |
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Laboratory Chemical Safety Summary :240 |
National Institute of Allergy and Infectious Diseases:Data |
WISER:UN 1990 |
WGK Germany:2 |
benzaldehyde |
Chemidplus:0000100527 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:100-52-7 |