5,5a,6,7,8,8a-hexahydro-6,6,7,8,8-pentamethyl-4H-indeno[5,4-D]isoxazole

5,5a,6,7,8,8a-hexahydro-6,6,7,8,8-pentamethyl-4H-indeno[5,4-D]isoxazole is an organic compound classified within the isoxazole chemical family. It presents as a complex bicyclic structure with multiple methyl substitutions, imparting unique characteristics to the molecule. Sensory evaluation describes its odor as woody with earthy and green nuances, accompanied by patchouli-like, cashmeran, and subtle aldehydic moss and amber notes, which contribute to a distinctive aromatic profile. This compound is indexed in chemical databases under controlled vocabularies such as PubChem, facilitating structural and property reference. Industrially, it is synthesized for research purposes rather than commercial fragrance or flavor production due to its specialized profile and application limitations.

This compound does not naturally occur in biological systems, and it is primarily of interest for informational and research applications. It is not intended or approved for use in fragrances or flavorings. Regulatory bodies track its safety data to inform usage restrictions. Standards including those from the REACH (EU) framework govern substances with limited or no direct consumer applications, emphasizing precautionary data collection. Its physicochemical profile enables exploration in chemical research contexts rather than commercial product formulation or biological incorporation.

The compound exhibits properties influenced by its saturated bicyclic isoxazole core and pentamethyl substitution pattern, affecting molecular stability, hydrophobicity, and vapor pressure. These features contribute to its woody and earthy organoleptic character, pertinent when considering formulation environments. Its volatility is moderate, aligning with its odor detection threshold and sensory impact. The molecular structure promotes chemical robustness under standard ambient conditions, with no significant hazard classifications reported according to OSHA HCS (US) guidelines. These properties restrict its practical applications predominantly to analytical and informational usage rather than consumer-oriented formulations.

None found

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
information only not used for fragrances or flavors
Recommendation for 5,5a,6,7,8,8a-hexahydro-6,6,7,8,8-pentamethyl-4H-indeno[5,4-D]isoxazole usage levels up to:
	not for fragrance use.
Recommendation for 5,5a,6,7,8,8a-hexahydro-6,6,7,8,8-pentamethyl-4H-indeno[5,4-D]isoxazole flavor usage levels up to:
	not for flavor use.

Safety references

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