acetal 318

Acetal 318, chemically named 3-(1-ethoxyethoxy)-3,7-dimethyl-1-octene, is a synthetic fragrance compound featuring the molecular formula C₁₄H₂₈O₂. It presents as a medium-strength floral odor with nuances described as sweet cardamom, fruity, and tropical. This compound is recognized under several synonyms including acetaldehyde ethyl 6-dihydrolinalyl acetal. It is associated with the PubChem database entry 163400, providing authoritative chemical and safety information. Typically sourced via chemical synthesis, Acetal 318 is widely employed in fragrance formulations to impart complex floral and aldehydic notes.

While Acetal 318 does not occur naturally, its synthetic production enables its use as a fragrance agent in perfumery and related applications. This compound contributes aldehydic, floral, and tropical fruit character to scent blends. Its odor profile supports uses mimicking various natural aromas such as apple, blackberry, jasmine, and tropical fruits, enhancing a broad range of fragrance concepts including chypre, oriental, and bouquet themes. According to the IFRA (Global) Code of Practice, its use in fragrance concentrates is recommended up to 2.0% concentration. Despite its numerous odor facets, Acetal 318 is not designated for flavoring purposes.

Acetal 318 exhibits a molecular weight of approximately 228.38 g/mol and a molecular formula of C₁₄H₂₈O₂. It has a boiling point range near 260 to 262°C at standard atmospheric pressure. Its vapor pressure at 25°C is low, measured at about 0.075 mmHg, indicating low volatility under ambient conditions. The compound is soluble in alcohol and shows limited water solubility, with an estimated value around 2.41 mg/L at 25°C. With a logP value near 4.65, Acetal 318 is moderately lipophilic, favoring partitioning into organic phases typical of fragrance formulations. The flash point is about 52.8°C (127°F), denoting its flammable nature, requiring attention during handling and formulation. Stability assessments suggest moderate resilience but recommend caution against alkaline conditions that could affect acetal stability.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View

Safety information

European information :
Most important hazard(s):
Xi - Irritant
R 10 - Flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for acetal 318 usage levels up to:
	2.0000 % in the fragrance concentrate.
Recommendation for acetal 318 flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):84029-93-6

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :163400

National Institute of Allergy and Infectious Diseases:Data

3-(1-ethoxyethoxy)-3,7-dimethyloct-1-ene

Chemidplus:0084029936