We have found 46587 results matching your criteria.
Please wait while we search...
  1. 1.
    General Material Information
  2. 2.
    PhysChem Properties
  3. 3.
    Occurrences
  4. 4.
    Organoleptic Properties
  5. 5.
    Suppliers
  6. 6.
    Potential Uses
  7. 7.
    Regulatory & Documentation
  8. 8.
    Safety Information
  9. 9.
    Other Information
  10. 10.
    Blenders & Components
  11. 11.
    Literature & References

6-amyl-alpha-pyrone

Chemical Structure

General Material Information

Preferred name 6-amyl-alpha-pyrone
Trivial Name 6-Pentyl-2H-pyran-2-one
Short Description 6-pentyl-2-pyrone
Formula C10 H14 O2
CAS Number 27593-23-3
FEMA Number 3696
Flavis Number 10.031
ECHA Number 248-552-3
FDA UNII 8JTW8HL4PJ
Nikkaji Number J47.697H
MDL MFCD00047551
COE Number 10967
xLogP3-AA 3.00 (est)
Bio Activity Summary External link
NMR Predictor External link
JECFA Food Flavoring 245 5-hydroxy-2,4-decadienoic acid delta-lactone
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 27593-23-3 ; 5-HYDROXY-2,4-DECADIENOIC ACID DELTA-LACTONE
Synonyms
  • 6 amyl alpha pyrone
  • 6-amyl-2-pyrone
  • 6-amyl-a-pyrone
  • 5-hydroxy-2,4-decadienoic acid d-lactone
  • 5-hydroxy-2,4-decadienoic acid delta-lactone
  • 6-( pent-1-yl)-2H-pyran-2-one
  • 6-pentyl-2-pyrone
  • 6-pentyl-2H-pyran-2-one
  • 6-N- pentyl-2H-pyran-2-one
  • 6-pentyl-a-pyrone
  • 6-pentyl-alpha-pyrone
  • 6-pentylpyran-2-one
  • 2H- pyran-2-one, 6-pentyl-
  • 6-pentylpyran-2-one
  • 2H-Pyran-2-one, 6-pentyl-
  • 6-Pentyl-2H-pyran-2-one
  • 6-Pentyl-α-pyrone
  • 6-n-Pentyl-α-pyrone
  • 6-Pentyl-2-pyrone
  • 6-(1-Pentyl)-2H-pyran-2-one
  • 6-n-Pentyl-2H-pyran-2-one

US / EU / FDA / JECFA / FEMA / Scholar / Patents

Google Scholar Start search
Google Books Start search
Google Patents Start search
Perfumer & Flavorists Start search
EU Patents Start search
PubMeb Start search
NCBI Start search

Literature & References

6-pentylpyran-2-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:27593-23-3
Pubchem (cid):33960
Pubchem (sid):134997872
Publications by Perfumer & Flavorist
6-Amyl-a-pyrone
Publications by US Patents
3,946,054 - Keto-ester composition

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB31085
FooDB:FDB003090
Export Tariff Code:2932.29.6000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 166.21998596191
Specific gravity @ 20 °C
Pounds per Gallon 8.431 to 8.464
Refractive Index 1.504 to 1.508 @ 20 °C
Boiling Point 285 to 286°C @ 760 mm Hg
Vapor Pressure 0.002 mmHg @ 25 °C
Flash Point TCC Value 110 °C TCC
logP (o/w) 1.808 est
Solubility
alcohol Yes
water, 742.4 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Tonka
tonka, lactonic, coconut, creamy, fatty, waxy, sweet, brown
General comment At 1.00 % in dipropylene glycol. tonka lactonic coconut creamy fatty waxy
Mosciano, Gerard P&F 16, No. 6, 43, (1991) Coconut creamy, sweet, brown with a fatty waxy nuance
Flavor Type: Creamy
sweet, creamy, coconut, mushroom, nutty
Mosciano, Gerard P&F 16, No. 6, 43, (1991) At 30.00 ppm. Sweet creamy, coconut, mushroom and nutty
General comment Sweet creamy coconut mushroom nutty

Occurrences

Potential Uses

Applications
Odor purposes Coconut, Cream, Fruit, Jasmin
Flavoring purposes Cheese blue cheese, Dairy, Milk, Mushroom, Nut, Yogurt
Other purposes Beautiful

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/39 - Wear suitable clothing and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
gavage-rat LD50 [sex: M,F] 5000 mg/kg
(Piccirillo & Hartman, 1980a

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 6-amyl-alpha-pyrone usage levels up to:
3.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 84.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.10 (μg/capita/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 13
Click here to view publication 13
average usual ppmaverage maximum ppm
baked goods: -0.20000
beverages(nonalcoholic): -0.20000
beverages(alcoholic): --
breakfast cereal: --
cheese: -0.20000
chewing gum: -0.50000
condiments / relishes: -0.50000
confectionery froastings: -0.20000
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: -0.05000
granulated sugar: --
gravies: -0.20000
hard candy: -0.20000
imitation dairy: -0.10000
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: -0.20000
seasonings / flavors: --
snack foods: --
soft candy: -0.10000
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 98 (FGE.98): Consideration of three ring-unsaturated delta-lactones
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):27593-23-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :33960
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
6-pentylpyran-2-one
Chemidplus:0027593233