Preferred name | 4-vinyl phenol |
Trivial Name | 4-Vinylphenol |
Short Description | p-vinylphenol |
Formula | C8 H8 O |
CAS Number | 2628-17-3 |
FEMA Number | 3739 |
Flavis Number | 4.057 |
ECHA Number | 220-103-6 |
FDA UNII | OA7V1SM8YL |
Nikkaji Number | J38.247G |
Beilstein Number | 0506844 |
MDL | MFCD00017593 |
COE Number | 11257 |
NMR Predictor | External link |
JECFA Food Flavoring | 711 p-vinylphenol |
FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
FDA Mainterm | 2628-17-3 ; P-VINYLPHENOL |
Synonyms |
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Google Books | Start search |
Google Patents | Start search |
Perfumer & Flavorists | Start search |
EU Patents | Start search |
PubMeb | Start search |
NCBI | Start search |
4-ethenylphenol | |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 2628-17-3 |
Pubchem (cid): | 62453 |
Pubchem (sid): | 135019290 |
Flavornet: | 2628-17-3 |
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
FDA Substances Added to Food (formerly EAFUS): | View |
CHEBI: | View |
CHEMBL: | View |
KEGG (GenomeNet): | C05627 |
HMDB (The Human Metabolome Database): | HMDB04072 |
FooDB: | FDB010540 |
YMDB (Yeast Metabolome Database): | YMDB01627 |
Export Tariff Code: | 2909.50.0090 |
Typical G.C. | |
VCF-Online: | VCF Volatile Compounds in Food |
ChemSpider: | View |
Wikipedia: | View |
Material listed in food chemical codex | No |
Molecular weight | 120.15096282959 |
Specific gravity | @ 25 °C |
Pounds per Gallon | |
Melting Point | 59 to 68°C @ 760 mm Hg |
Boiling Point | 163 to 168°C @ 0.5 mm Hg |
Vapor Pressure | 0.168 mmHg @ 25 °C |
Flash Point TCC Value | 60 °C TCC |
logP (o/w) | 2.615 est |
Solubility | |
alcohol | Yes |
water | Yes |
water, 3302 mg/L @ 25 °C (est) | Yes |
Odor Type: Phenolic | |
chemical, phenolic, medicinal, sweet, musty, meaty | |
General comment | At 0.01 % in propylene glycol. chemical phenolic medicinal sweet |
Mosciano, Gerard P&F 15, No. 1, 19, (1990) | Chemical, phenolic, medicinal with sweet musty and meaty nuances |
Flavor Type: Phenolic | |
phenolic, medicinal, spicy | |
Mosciano, Gerard P&F 15, No. 1, 19, (1990) | At 60.00 ppm. Phenolic, medicinal, spicy |
Used in chewing gum at 10ppm, bakery and meat products at 5ppm, desserts and confectionery at 2-3ppm, and alcoholic beverages at 0.5%. | Sweet vanilla |
(data available) |
Applications | |
Odor purposes | Fruit |
Flavoring purposes | Bakery , Beverage , Coffee , Grain , Meat , Seafood , Tea , Vegetable , Wine |
Other purposes | Chewing gum , Confection |
Cosmetic purposes | Perfuming agents |
Preferred SDS: View | |
European information : | |
Most important hazard(s): | |
Xn - Harmful. | |
R 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R 34 - Causes burns. R 42/43 - May cause sensitization by inhalation and skin contact. S 02 - Keep out of the reach of children. S 23 - Do not breath vapour. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. S 53 - Avoid exposure - obtain special instructions before use. | |
Hazards identification | |
Classification of the substance or mixture | |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
None found. | |
GHS Label elements, including precautionary statements | |
Pictogram | |
Hazard statement(s) | |
None found. | |
Precautionary statement(s) | |
None found. | |
Oral/Parenteral Toxicity: | |
gavage-rat LD50 [sex: M,F] > 5000 mg/kg (Piccirillo & Hartman, 1982) | |
Dermal Toxicity: | |
skin-rabbit LDLo 200 mg/kg SKIN AND APPENDAGES (SKIN): CORROSIVE: AFTER TOPICAL EXPOSURE United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1285-0579S | |
Inhalation Toxicity: | |
Not determined |
Category: | |||
flavor and fragrance agents | |||
RIFM Fragrance Material Safety Assessment: Search | |||
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.12 (μg/capita/day) | ||
Maximised Survey-derived Daily Intakes (MSDI-USA): | 6.00 (μg/capita/day) | ||
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
publication number: 13 | |||
Click here to view publication 13 | |||
average usual ppm | average maximum ppm | ||
baked goods: | - | 5.00000 | |
beverages(nonalcoholic): | - | 1.50000 | |
beverages(alcoholic): | - | 0.50000 | |
breakfast cereal: | - | - | |
cheese: | - | - | |
chewing gum: | - | 10.00000 | |
condiments / relishes: | - | - | |
confectionery froastings: | - | 2.00000 | |
egg products: | - | - | |
fats / oils: | - | - | |
fish products: | - | - | |
frozen dairy: | - | 2.50000 | |
fruit ices: | - | - | |
gelatins / puddings: | - | 2.00000 | |
granulated sugar: | - | - | |
gravies: | - | 5.00000 | |
hard candy: | - | 2.00000 | |
imitation dairy: | - | 3.00000 | |
instant coffee / tea: | - | - | |
jams / jellies: | - | - | |
meat products: | - | 5.00000 | |
milk products: | - | - | |
nut products: | - | 2.00000 | |
other grains: | - | - | |
poultry: | - | - | |
processed fruits: | - | - | |
processed vegetables: | - | - | |
reconstituted vegetables: | - | - | |
seasonings / flavors: | - | - | |
snack foods: | - | - | |
soft candy: | - | - | |
soups: | - | - | |
sugar substitutes: | - | - | |
sweet sauces: | - | 2.50000 |
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 22 (FGE.22): Ring-substituted phenolic substances from chemical groups 21 and 25 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
Flavouring Group Evaluation 58 (FGE.58) Consideration of phenol derivatives evaluated by JECFA (55th meeting) structurally related to ring substituted phenolic substances evaluated by EFSA in FGE.22 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 60 (FGE.60): Consideration of eugenol and related hydroxyallylbenzene derivatives evaluated by JECFA (65th meeting) structurally related to ring- substituted phenolic substances evaluated by EFSA in FGE.22 (2006) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 22, Revision 1 (FGE.22Rev1): Ring-substituted phenolic substances from chemical groups 21 and 25 View page or View pdf |
EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA Substance Registry Services (TSCA):2628-17-3 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :62453 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:2 |
4-ethenylphenol |
Chemidplus:0002628173 |
RTECS:SN3800000 for cas# 2628-17-3 |