2,4-dimethyl cyclohexyl methyl acetate

2,4-dimethyl cyclohexyl methyl acetate is a synthetic aromatic ester characterized by the molecular formula C₁₁H₂₀O₂. Recognized for its floral and woody scent profile with subtle sweet and grapefruit undertones, it exhibits moderate odor strength and a substantivity of approximately four hours at pure concentration. Commonly known under synonyms such as dihydrofloralate (IFF) and cyclohexanemethanol, 2,4-dimethyl-, 1-acetate, this compound is predominantly sourced via chemical synthesis processes tailored for fragrance use. Its presence in perfuming agents is notable due to its versatile odor notes that enhance floral and citrus accords. Reliable chemical and structural information is accessible via databases like PubChem.

While 2,4-dimethyl cyclohexyl methyl acetate does not naturally occur in biological systems, it plays an important role in the fragrance industry as a synthetic aroma compound. Its medium-strength floral and woody odor qualities, complemented by sweet and grapefruit nuances, make it suitable for enhancing fragrances with floral, fruity, herbal, minty, and woody facets. This compound is approved for use as a perfuming agent under the IFRA (Global) standards, which recommend concentration limits up to 20% in fragrance concentrates. It is not intended for flavor applications. Such regulatory frameworks guide its inclusion in consumer and professional fragrance formulations to achieve desired sensory profiles while maintaining compliance.

2,4-dimethyl cyclohexyl methyl acetate displays physical and chemical properties critical to its formulation and application. It has a moderate molecular weight near 184.28 Da and an estimated logP of approximately 3.8, indicating moderate lipophilicity. The compound’s specific gravity ranges from 0.932 to 0.94 at 25°C and exhibits a refractive index between 1.445 and 1.45 at 20°C, relevant for analytical identification. Low vapor pressure around 0.1 mmHg at 25°C underlines its limited volatility, and a flash point near 89°C (192°F) suggests moderate flammability risk. Solubility data reveal good solubility in alcohol, but notably low solubility in water, influencing its behavior in formulations. Stability assessments indicate compatibility with various cosmetic preparation types, including lotions, antiperspirants, shampoos, and detergents, reinforcing its versatility in fragrance use.

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Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2,4-dimethyl cyclohexyl methyl acetate usage levels up to:
	20.0000 % in the fragrance concentrate.
Recommendation for 2,4-dimethyl cyclohexyl methyl acetate flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

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Toxicology Citations:Search

EPA Substance Registry Services (TSCA):67634-22-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :106746

National Institute of Allergy and Infectious Diseases:Data

(2,4-dimethylcyclohexyl)methyl acetate

Chemidplus:0067634224