We have found
46587
results matching your criteria.
Please wait while we search...
methyl isoeugenol
General Material Information
| Preferred name | methyl isoeugenol |
| Trivial Name | Methylisoeugenol |
| Short Description | 1,2-dimethoxy-4-(prop-1-enyl)benzene |
| Formula | C11 H14 O2 |
| CAS Number | 93-16-3 |
| FEMA Number | 2476 |
| ECHA Number | 202-224-6 |
| FDA UNII | 46RN7Q97DE |
| Beilstein Number | 0880472 |
| MDL | MFCD00009282 |
| COE Number | 186 |
| NMR Predictor | External link |
| JECFA Food Flavoring | 1266 isoeugenyl methyl ether |
| FDA Patent | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm | 93-16-3 ; ISOEUGENYL METHYL ETHER |
| Synonyms |
|
US / EU / FDA / JECFA / FEMA / Scholar / Patents
| Google Scholar | Start search |
| Google Books | Start search |
| Google Patents | Start search |
| Perfumer & Flavorists | Start search |
| EU Patents | Start search |
| PubMeb | Start search |
| NCBI | Start search |
Literature & References
| 1,2-dimethoxy-4-prop-1-enylbenzene | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 93-16-3 |
| Pubchem (cid): | 7128 |
| Pubchem (sid): | 134972689 |
| Pherobase: | View |
Other Information
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| KEGG (GenomeNet): | C10478 |
| HMDB (The Human Metabolome Database): | HMDB41553 |
| FooDB: | FDB021536 |
| Export Tariff Code: | 2909.30.0000 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Suppliers
PhysChem Properties
| Material listed in food chemical codex | Yes |
| Molecular weight | 178.23098754883 |
| Specific gravity | @ 25 °C |
| Pounds per Gallon | 8.712 to 8.779 |
| Specific gravity | @ 20 °C |
| Pounds per Gallon | 8.731 to 8.797 |
| Refractive Index | 1.566 to 1.569 @ 20 °C |
| Melting Point | 16 to 17°C @ 760 mm Hg |
| Boiling Point | 262 to 264°C @ 760 mm Hg |
| Vapor Pressure | 0.011 mmHg @ 25 °C |
| Flash Point TCC Value | 104.44 °C TCC |
| logP (o/w) | 3.049 est |
| Shelf life | 24 months (or longer if stored properly.) |
| Storage notes | Store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Solubility | |
| fixed oils | Yes |
| paraffin oil | Yes |
| water, 169.1 mg/L @ 25 °C (est) | Yes |
| glycerin | No |
| propylene glycol | No |
| Stability | |
| non-discoloring in most media | Unspecified |
Organoleptic Properties
| Odor Type: Spicy | |
| spicy, clove, floral, carnation, woody | |
| Odor strength | medium |
| Substantivity | 240 hour(s) at 100.00 % |
| Luebke, William tgsc, (1988) | At 100.00 %. spicy clove blossom carnation woody |
| Flavor Type: Spicy | |
| spicy, clove, resinous, galanga, smoky, woody, powdery | |
| Luebke, William tgsc, (1988) | Spicy warm clove resinous galanga smoky woody powdery |
| Useful in: brown others, vanilla, savory spices, fruity red, fruity yellow, fruity tropical, sweet others, alcoholics. | Spicy, woody, smoky, tar-like |
| General comment | Spicy, woody, smoky, fatty |
Occurrences
| (data available) |
Potential Uses
| Applications | |
| Odor purposes | Abronia, Amber, Angel essence, Bay rum, Blackberry, Carnation, Cassia, Christmas, Currant, Floral, Gardenia, Honeysuckle, Hyacinth, Leather russian leather, Lilac, Mulberry, Musk, Myrrh, Narcissus, Orange blossom, Orchid, Peony, Poppy, Potpourri, Raspberry, Raspberry black raspberry, Rose, Sandalwood, Spice, Strawberry, Sweet grass, Vanilla, Woody, Ylang ylang |
| Other purposes | Bellodgia, Chanel #5, Fixer, Tide |
| Cosmetic purposes | Perfuming agents |
Safety Information
Safety information
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| None - None found. | |
| S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| Acute toxicity, Oral (Category 4), H302 | |
| GHS Label elements, including precautionary statements | |
| Pictogram |  |
| Signal word | Warning |
| Hazard statement(s) | |
| H302 - Harmful if swallowed | |
| Precautionary statement(s) | |
| P264 - Wash skin thouroughly after handling. P270 - Do not eat, drink or smoke when using this product. P301 + P312 - IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P330 - Rinse mouth. P501 - Dispose of contents/ container to an approved waste disposal plant. | |
| Human Experience: | |
| 8 % solution: no irritation or sensitization. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 2500 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 865, 1975. intravenous-mouse LD50 181 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 199, Pg. 226, 1972. intraperitoneal-mouse LD50 570 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 199, Pg. 226, 1972. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 865, 1975. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in use information
| Category: | |||
| flavor and fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for methyl isoeugenol usage levels up to: | |||
| 8.0000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 109.00 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 129.00 (μg/capita/day) | ||
| Structure Class: | III | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 18.00000 | |
| beverages(nonalcoholic): | - | 4.00000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | 110.00000 | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 7.70000 | |
| fruit ices: | - | 7.70000 | |
| gelatins / puddings: | - | 0.10000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 13.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety references
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Scientific Opinion on Flavouring Group Evaluation 81 (FGE.81): Consideration of hydroxypropenylbenzenes evaluated by JECFA (61st meeting) structurally related to 2-methoxy-4-(prop-1-enyl)phenyl 3-methylbutyrate from chemical group 17 evaluated by EFSA in FGE.30 View page or View pdf |
| Scientific Opinion on the safety and efficacy of aromatic ethers including anisole derivatives (chemical group 26) when used as feed additives for all animal species View page or View pdf |
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):93-16-3 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :7128 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 1,2-dimethoxy-4-prop-1-enylbenzene |
| Chemidplus:0000093163 |
| RTECS:CZ7000000 for cas# 93-16-3 |