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2'-hydroxyacetophenone

Chemical Structure

General Material Information

Preferred name 2'-hydroxyacetophenone
Trivial Name 2′-Hydroxyacetophenone
Short Description o-acetylphenol
Formula C8 H8 O2
CAS Number 118-93-4
FEMA Number 3548
Flavis Number 7.124
ECHA Number 204-288-0
FDA UNII 3E533Z76W0
Nikkaji Number J5.308B
Beilstein Number 0386123
MDL MFCD00002219
COE Number 11784
Bio Activity Summary External link
NMR Predictor External link
JECFA Food Flavoring 727 2'-hydroxyacetophenone
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 118-93-4 ; 2-HYDROXYACETOPHENONE
Synonyms
  • 2-acetophenol
  • acetophenone, 2'-hydroxy-
  • 2-acetyl phenol
  • ortho- acetyl phenol
  • 1-acetyl-2-hydroxybenzene
  • 2-acetylphenol
  • o- acetylphenol
  • ethanone, 1-(2-hydroxyphenyl)-
  • o- hydroxy acetophenone
  • 2-hydroxyacetophenone
  • o- hydroxyacetophenone
  • ortho- hydroxyacetophenone
  • 2-hydroxyphenyl methyl ketone
  • ortho- hydroxyphenyl methyl ketone
  • 1-(2-hydroxyphenyl) ethanone
  • 1-(2-hydroxyphenyl)ethan-1-one
  • 1-(2-hydroxyphenyl)ethanone
  • 2-hydroxyphenylmethyl ketone
  • o- hydroxyphenylmethyl ketone
  • methyl 2-hydroxyphenyl ketone
  • 1-(2-hydroxyphenyl)ethanone
  • Acetophenone, 2′-hydroxy-
  • Acetophenone, o-hydroxy-
  • o-Hydroxyacetophenone
  • 2′-Hydroxyacetophenone
  • o-Acetylphenol
  • 2-Acetylphenol
  • o-Hydroxyphenyl methyl ketone
  • 2-Hydroxyphenyl methyl ketone
  • 2-Hydroxyacetophenone
  • 2-Hydroxyphenylethanone
  • NSC 16933
  • NSC 44452
  • NSC 83568
  • NSC 9263
  • o-Hydroxyhypnone
  • 1-(6-Hydroxyphenyl)ethanone
  • 1-(2-Hydroxyphenyl)ethan-1-one
  • 1-Acetyl-2-hydroxybenzene

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

1-(2-hydroxyphenyl)ethanone
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:118-93-4
Pubchem (cid):8375
Pubchem (sid):134974041
Pherobase:View
Publications by US Patents
3,946,080 - Flavouring and perfuming ingredients
3,952,024 - Furfurylthioacetone
Publications by PubMed
Differentiation of Manuka Honey from Kanuka Honey and from Jelly Bush Honey using HS-SPME-GC/MS and UHPLC-PDA-MS/MS.
Crystallization and preliminary X-ray diffraction analysis of (R)-carbonyl reductase from Candida parapsilosis.
Particle size and shape modification of hydroxyapatite nanostructures synthesized via a complexing agent-assisted route.
Bis(4-hydroxy-2H-chromen-2-one): synthesis and effects on leukemic cell lines proliferation and NF-κB regulation.
New ruthenium(II) carbonyl complexes bearing disulfide Schiff base ligands and their applications as catalyst for some organic transformations.
Combined experimental and theoretical studies on the X-ray crystal structure, FT-IR, 1H NMR, 13C NMR, UV-Vis spectra, NLO behavior and antimicrobial activity of 2-hydroxyacetophenone benzoylhydrazone.
Synthesis of isoflavones by room-temperature nickel-catalyzed cross-couplings of 3-iodo(bromo)chromones with arylzincs.
2,2,6,6-Tetramethylpiperidine-catalyzed, ortho-selective chlorination of phenols by sulfuryl chloride.
Photochromic cycle of 2'-hydroxyacetophenone azine studied by absorption and emission spectroscopy in different solvents.
The role of a Schiff base scaffold, N-(2-hydroxy acetophenone) glycinate-in overcoming multidrug resistance in cancer.
Preparation of crystal-like periodic mesoporous phenylene-silica derivatized with ferrocene and its use as a catalyst for the oxidation of styrene.
Synthesis, docking study and relaxant effect of 2-alkyl and 2-naphthylchromones on rat aorta and guinea-pig trachea through phosphodiesterase inhibition.
Optimized expression of (S)-carbonyl reductase in Pichia pastoris for efficient production of (S)-1-phenyl-1, 2-ethanediol.
Acaricidal potentials of active properties isolated from Cynanchum paniculatum and acaricidal changes by introducing functional radicals.
New nickel(II) and copper(II) complexes with unsymmetrical Schiff bases derived from (1R,2R)(-)cyclohexanediamine and the application of Cu(II) complexes for hybrid thin layers deposition.
Synthesis, spectral and antimicrobial activity of Zn(II) complexes with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole and benzaldehyde/2-hydroxyacetophenone/indoline-2,3-dione.
1, 5-Bis (2-hydroxyacetophenone)thiocarbohydrazone: a novel colorimetric and fluorescent dual-mode chemosensor for the recognition of fluoride.
Flame atomic absorption spectrometric (FAAS) determination of copper, iron and zinc in food samples after solid-phase extraction on Schiff base-modified duolite XAD 761.
Efficient one-step production of (S)-1-phenyl-1,2-ethanediol from (R)-enantiomer plus NAD(+)-NADPH in-situ regeneration using engineered Escherichia coli.
A simple route to synthesize mesoporous ZSM-5 templated by ammonium-modified chitosan.
Palladium-catalyzed carbonylation reaction of aryl bromides with 2-hydroxyacetophenones to form flavones.
Co(II), Cd(II), Hg(II) and U(VI)O₂ complexes of o-hydroxyacetophenone[N-(3-hydroxy-2-naphthoyl)] hydrazone: physicochemical study, thermal studies and antimicrobial activity.
Accessibility and selective stabilization of the principal spin states of iron by pyridyl versus phenolic ketimines: modulation of the 6A1 ↔ 2T2 ground-state transformation of the [FeN4O2]+ chromophore.
Isolation and identification of the metabolites of paeonol in human urine.
Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H(2)dampt).
Organocatalytic Dakin oxidation by nucleophilic flavin catalysts.
Template synthesis, spectroscopic characterization and preliminary insulin-mimetic activity of oxovanadium(IV) complexes with N₂O₂ diazadioxa macrocycles.
Molecular and catalytic properties of 2,4'-dihydroxyacetophenone dioxygenase from Burkholderia sp. AZ11.
The molecular interaction of a copper chelate with human P-glycoprotein.
Synthesis of the first heterometalic star-shaped oxido-bridged MnCu3 complex and its conversion into trinuclear species modulated by pseudohalides (N3(-), NCS- and NCO-): structural analyses and magnetic properties.
Synthesis, spectral characterization and biological activity of zinc(II) complexes with 3-substituted phenyl-4-amino-5-hydrazino-1, 2, 4-triazole Schiff bases.
Synthesis, characterization and biological activities of Cu(II), Co(II), Mn(II), Fe(II), and UO2(VI) complexes with a new Schiff Base hydrazone: O-hydroxyacetophenone-7-chloro-4-quinoline hydrazone.
[Expression and subcellular localization of (R)- and (S)-specific carbonyl reductases from Candida parapsilosis in Saccharomyces cerevisia].
[Broader substrate specifity of Candida parapsilosis SCR II for catalyzing acetophenone derivatives by site-directed mutagenesis].
Weak interactions modulating the dimensionality in supramolecular architectures in three new nickel(II)-hydrazone complexes, magnetostructural correlation, and catalytic potential for epoxidation of alkenes under phase transfer conditions.
Bivalent transition metal complexes of o-hydroxyacetophenone [N-(3-hydroxy-2-naphthoyl)] hydrazone: spectroscopic, antibacterial, antifungal activity and thermogravimetric studies.
An in vitro and in vivo study of a novel zinc complex, zinc N-(2-hydroxyacetophenone)glycinate to overcome multidrug resistance in cancer.
Novel anti-Prelog stereospecific carbonyl reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones.
Exploration on asymmetric synthesis of flavanone catalyzed by (S)-pyrrolidinyl tetrazole.
Redox active copper chelate overcomes multidrug resistance in T-lymphoblastic leukemia cell by triggering apoptosis.
Synthesis and biological evaluation of 4-styrylcoumarin derivatives as inhibitors of TNF-α and IL-6 with anti-tubercular activity.
Isolation of four new CoII/CoIII and NiII complexes with a pentadentate Schiff base ligand: syntheses, structural descriptions and magnetic studies.
Pharmacological activity of novel 2-hydroxyacetophenone isatin derivatives on cardiac and vascular smooth muscles in rats.
Dithiocarbazate complexes with the [M(PPh3)]2+ (M = Pd or Pt) moiety: synthesis, characterization and anti-Trypanosoma cruzi activity.
Carbonyl reductase SCRII from Candida parapsilosis catalyzes anti-Prelog reaction to (S)-1-phenyl-1,2-ethanediol with absolute stereochemical selectivity.
A unique example of structural and magnetic diversity in four interconvertible copper(II)-azide complexes with the same schiff base ligand: a monomer, a dimer, a chain, and a layer.
HPLC method for simultaneous determination of impurities and degradation products in zonisamide.
Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs.
Complexes of 2-hydroxyacetophenone semicarbazones: A novel series of superoxide dismutase mimetics.
[Improved expression and catalytic efficiency of (R)-carbonyl reductase in Escherichia coli by secondary structure optimization of mRNA translation initiation region].
[Gene cloning and expression of a novel (S)-specific carbonyl reductase].
Silica gel-catalyzed one-pot syntheses in water and fluorescence properties studies of 5-amino-2-aryl-3H-chromeno[4,3,2-de][1,6]naphthyridine-4-carbonitriles and 5-amino-2-aryl-3H-quinolino[4,3,2-de][1,6]naphthyridine-4-carbonitriles.
A preconcentration procedure for copper, nickel and chromium ions in some food and environmental samples on modified Diaion SP-850.
Na(I)/Cu(I-II) heterometallic cages interconnected by unusual linear 2-coordinate OCN-Cu(I)-NCO links: synthesis, structural, magnetostructural correlation and computational studies.
Detection and characterization of a glutathione conjugate of a novel copper complex.
Antibacterial compounds from the root of the indigenous Australian medicinal plant Carissa lanceolata R.Br.
Cloud point extraction and flame atomic absorption spectrometry determination of trace amounts of copper(II) ions in water samples.
Design of conformationally constrained azole antifungals: efficient synthesis and antifungal activity of trans-3-imidazolylflavanones.
[Co-expression of formate dehydrogenase from Candida boidinii and (R)-specific carbonyl reductase from Candida parapsilosis CCTCC M203011 in Escherichia coli].
Improved production of (R)-1-phenyl-1,2-ethanediol by a codon-optimized R-specific carbonyl reductase from Candida parapsilosis in Escherichia coli.
Ser67Asp and His68Asp substitutions in candida parapsilosis carbonyl reductase alter the coenzyme specificity and enantioselectivity of ketone reduction.
Flame atomic absorption spectrometric determination of zinc, nickel, iron and lead in different matrixes after solid phase extraction on sodium dodecyl sulfate (SDS)-coated alumina as their bis (2-hydroxyacetophenone)-1, 3-propanediimine chelates.
Sodium dodecyl sulfate coated poly (vinyl) chloride: an alternative support for solid phase extraction of some transition and heavy metals.
Synthesis and spectral investigations of vanadium(IV/V) complexes derived from an ONS donor thiosemicarbazone ligand.
Energetics of the O-H bond and of intramolecular hydrogen bonding in HOC6H4C(O)Y (Y = H, CH3, CH2CH=CH2, C[triple bond]CH, CH2F, NH2, NHCH3, NO2, OH, OCH3, OCN, CN, F, Cl, SH, and SCH3) compounds.
Synthesis of two new linear trinuclear Cu(II) complexes: mechanism of magnetic coupling through hybrid B3LYP functional and CShM studies.
Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity.
Polymetallic clusters of iron(III) with derivatised salicylaldoximes.
Synthesis, spectral and antimicrobial studies of bis(cyclopentadienyl)titanium(IV) derivatives with Schiff bases derived from 2-amino-5-phenyl-1,3,4-thiadiazole.
Design and synthesis of propeller-shaped dispiroisoxazolinopiperidinochromanones.
On the inoperativeness of the ESIPT process in the emission of 1-hydroxy-2-acetonaphthone: a reappraisal.
Resonance Raman intensity analysis of the excited-state proton-transfer dynamics of 2-hydroxybenzaldehyde in the charge-transfer/proton-transfer absorption band.
Highly selective and sensitive copper membrane electrode based on a new synthesized Schiff base.
Synthesis and photoluminescence properties of novel europium complexes of 2'-hydroxyacetophenone and 4,6-diacetylresorcinol.
Purification, characterization, gene cloning, and expression of a novel alcohol dehydrogenase with anti-prelog stereospecificity from Candida parapsilosis.
Resonance Raman intensity analysis of the excited state proton transfer dynamics of 2-nitrophenol in the charge-transfer band absorption.
A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo.
2-Hydroxyacetophenone 4-phenylthiosemicarbazone.
Bis(2-hydroxyacetophenone)ethylenediimine as a neutral carrier in a coated-wire membrane electrode for lead(II).
Reaction coordinate analysis for beta-diketone cleavage by the non-heme Fe2+-dependent dioxygenase Dke1.
Dinuclear triple helicates with diazine ligands: X-ray structural, electrochemical, and magnetic studies.
Preparation of ordered large pore SBA-15 silica functionalized with aminopropyl groups through one-pot synthesis.
Novel salicylaldehyde-based mineral-supported expeditious synthesis of benzoxazin-2-ones.
Design and synthesis of two pyrazole libraries based on o-hydroxyacetophenones.
Estimations of excited state dipole moments of conformers in some o-substituted acetophenones by solvato-chromic shifts.
Using model complexes to augment and advance metalloproteinase inhibitor design.
Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.
Unexpected migration and oxidative cyclization of substituted 2-acetophenone triflates under basic conditions: synthetic and mechanistic insights.
Construction of Escherichia coli strains for conversion of nitroacetophenones to ortho-aminophenols.
Unprecedented chemical transformation of semicarbazones mediated by Wilkinson's catalyst.
6-(2-Hydroxybenzoyl)-5-(pyrrol-2-yl)-3H-pyrrolizine.
Spectral studies and structure of a 2-hydroxyacetophenone 3-hexamethyleneiminyl thiosemicarbazonate(-2) copper(II) complex containing 1,10-phenanthroline.
Recent progress in asymmetric two-center catalysis.
Efficient liquid-phase synthesis of 2'-hydroxychalcones.
Effects of 4,4-dimethyl-5,8-dihydroxynaphtalene-1-one and 4,4-dimethyl-5,8-dihydroxytetralone derivatives on tumor cell respiration.
A comparative photomechanistic study (spin trapping, EPR spectroscopy, transient kinetics, photoproducts) of nucleoside oxidation (dG and 8-oxodG) by triplet-excited acetophenones and by the radicals generated from alpha-oxy-substituted derivatives through Norrish-type I cleavage.
19F NMR study on the biological Baeyer-Villiger oxidation of acetophenones.
Multifunctional asymmetric catalysis.
19F NMR study on the biological Baeyer-Villiger oxidation of acetophenones.
Pyriform cortex beta-waves: odor-specific sensitization following repeated olfactory stimulation.
Bis(4,7-dimethyl-1,10-phenanthroline) sulfatooxovanadium(IV) as a novel apoptosis-inducing anticancer agent.
Spermicidal activity of oxovanadium(IV) complexes of 1, 10-phenanthroline, 2,2'-bipyridyl, 5'-bromo-2'-hydroxyacetophenone and derivatives in humans.
Enzymatic resolution of 1-phenyl-1,2-ethanediol by enantioselective oxidation: overcoming product inhibition by continuous extraction.
Toluene and ethylbenzene oxidation by purified naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816-4.
Synthetic and structure/activity studies on acid-substituted 2-arylphenols: discovery of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- hydroxyphenoxy]-propoxy]phenoxy]benzoic acid, a high-affinity leukotriene B4 receptor antagonist.
Spectral Studies and Bactericidal, Fungicidal, Insecticidal and Parasitological Activities of Organotin(IV) Complexes of Thio Schiff Bases Having no Donor Atoms.
Synthesis and pharmacological evaluation of some potential beta-adrenolytics derivated from o-hydroxyacetophenone.
Further isolation of glycosides from Cynanchum hancockianum.
Synthesis and evaluation of technetium-99m monocationic mixed ligand complexes of phenyl substituted/condensed tetradentate Schiff's bases and trimethylphosphine.
Metabolism of Dibenzofuran by Pseudomonas sp. Strain HH69 and the Mixed Culture HH27.
3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists.
Initial reactions of xanthone biodegradation by an Arthrobacter sp.
2-Hydroxyacetophenone: principal root volatile of the East African medicinal plant, Carissa edulis.
Derivatization of carboxylic acids by reaction with 4'-bromophenacyl trifluoromethanesulfonate prior to determination by high-performance liquid chromatography.
Extraction and spectrophotometric determination of nickel with 2-hydroxyacetophenone oxime and simultaneous determination of copper and nickel.
Inhibitors of hepatic mixed function oxidase. 3. Inhibition of hepatic microsomal aniline hydroxylase and aminopyrine demethylase by 2,6- and 2,4-dihydroxyphenyl alkyl ketones and related compounds.
[Condensation of 2-hydroxyacetophenone derivatives to Mannich bases with 4-chromanones].
[Some esters of 2-hydroxyacetophenone with vascular effects and anti-permeability effects].

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB32568
FooDB:FDB010500
Export Tariff Code:2914.50.3000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 136.15016174316
Specific gravity @ 20 °C
Pounds per Gallon 9.439 to 9.464
Refractive Index 1.557 to 1.561 @ 20 °C
Melting Point 4 to 6°C @ 760 mm Hg
Vapor Pressure 0.086 mmHg @ 25 °C
Vapor Density 4.7
Flash Point TCC Value 106.11 °C TCC
logP (o/w) 1.92
Solubility
alcohol Yes
water, 7571 mg/L @ 25 °C (est) Yes
water No

Organoleptic Properties

Odor Type: Phenolic
phenolic, sweet, hawthorn, tobacco, honey, herbal, sharp, almond bitter almond, cherry, tropical, melon
Odor strength medium , recommend smelling in a 10.00 % solution or less
Substantivity 360 hour(s) at 100.00 %
Luebke, William tgsc, (1987) At 10.00 % in dipropylene glycol. phenolic sweet hawthorn tobacco honey herbal
Mosciano, Gerard P&F 23, No. 5, 49, (1998) At 2.00 %. Phenolic, sharp, benzaldehyde, cherry pit, tropical, melon with a tobacco afternote
Flavor Type: Naphthyl
naphthyl, cinnamon, cherry, coumarinic, phenolic, tobacco, honey
Mosciano, Gerard P&F 23, No. 5, 49, (1998) At 5.00 ppm. Naphthyl, cinnamon, cherry pit, coumarin, phenolic, tobacco and honey

Occurrences

Potential Uses

Applications
Odor purposes Almond , Cassia , Cinnamon , Coffee , Hawthorn , Hay new mown hay , Leather , Mimosa , Papaya , Peppermint , Spruce , Tobacco , Woody
Flavoring purposes Tomato , Tropical
Other purposes Snowdrop tree

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 100 mg/kg
National Technical Information Service. Vol. AD277-689

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2'-hydroxyacetophenone usage levels up to:
3.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.12 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.01 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 11
Click here to view publication 11
average usual ppmaverage maximum ppm
baked goods: -0.20000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: -0.10000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: -0.10000
hard candy: --
imitation dairy: --
instant coffee / tea: -0.10000
jams / jellies: --
meat products: -0.10000
milk products: --
nut products: --
other grains: --
poultry: -0.10000
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: -0.10000
snack foods: -0.20000
soft candy: --
soups: -0.10000
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 22 (FGE.22): Ring-substituted phenolic substances from chemical groups 21 and 25 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 58 (FGE.58) Consideration of phenol derivatives evaluated by JECFA (55th meeting) structurally related to ring substituted phenolic substances evaluated by EFSA in FGE.22 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 60 (FGE.60): Consideration of eugenol and related hydroxyallylbenzene derivatives evaluated by JECFA (65th meeting) structurally related to ring- substituted phenolic substances evaluated by EFSA in FGE.22 (2006)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 22, Revision 1 (FGE.22Rev1): Ring-substituted phenolic substances from chemical groups 21 and 25
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):118-93-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8375
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1-(2-hydroxyphenyl)ethanone
Chemidplus:0000118934
RTECS:AM8575000 for cas# 118-93-4