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laevo-cysteine

Chemical Structure

General Material Information

Preferred name laevo-cysteine
Trivial Name L-(+)-Cysteine
Short Description propanoic acid, 2-amino-3-mercapto-, (R)-
Formula C3 H7 N O2 S
CAS Number 52-90-4
Deleted CAS Number 154605-72-8
FEMA Number 3263
Flavis Number 17.033
ECHA Number 200-158-2
FDA UNII K848JZ4886
Nikkaji Number J9.167G
Beilstein Number 1721408
MDL MFCD00064306
COE Number 10464
Bio Activity Summary External link
NMR Predictor External link
JECFA Food Flavoring 1419 L-cysteine
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 52-90-4 ; L-CYSTEINE
Synonyms
  • (+)-2-amino-3-mercaptopropionic acid
  • (2R)-2-amino-3-mercaptopropanoic acid
  • (2R)-2-amino-3-sulfanyl propanoic acid
  • (2R)-2-amino-3-sulfanylpropanoic acid
  • (2R)-2-amino-3-sulfanylpropanoic acid
  • (2R)-2-ammonio-3-mercaptopropanoate
  • (2R)-2-ammonio-3-sulfanylpropanoate
  • (2R)-L-cysteine
  • (R)- cysteine
  • (R)-(+)-cysteine
  • (R)-2-amino-3-mercapto-propanoic acid
  • (R)-2-amino-3-mercapto-propionic acid
  • (R)-2-amino-3-mercaptopropanoic acid
  • (R)-2-amino-3-mercaptopropionic acid
  • 3-mercapto-L-alanine
  • a-amino-b-thiolpropionic acid
  • ajipure cysteine
  • alpha amino-beta-mercaptopropanoic acid
  • amino acid, cysteine
  • b-mercaptoalanine
  • beta-amino-beta-mercaptopropionic acid
  • beta-mercaptoalanine
  • cisteinum
  • hydrogen L-cysteinate
  • L-(+)-cysteine
  • L-2-amino-3-mercaptopropionic acid
  • L-alpha-amino-beta-mercaptopropanoic acid
  • L-alpha-amino-beta-mercaptopropionic acid
  • L-cysteine
  • L-cysteine base
  • L-cysteine free base
  • laevo-alpha-amino-beta-mercaptopropanoic acid
  • laevo-alpha-amino-beta-mercaptopropionic acid
  • laevo-alpha-amino-beta-thiol propionic acid
  • propanoic acid, 2-amino-3-mercapto-, (R)-
  • Leovo-cycteine
  • Cysteine, L-
  • Half-cystine
  • β-Mercaptoalanine
  • Thioserine
  • Cysteine
  • Cystein
  • L-Alanine, 3-mercapto-
  • NSC 8746
  • (R)-Cysteine
  • 2-Amino-3-mercaptopropionic acid
  • L-Cys
  • E 920
  • (R)-2-Amino-3-sulfanylpropanoic acid
  • 2-Amino-3-mercaptopropanoic acid
  • 11: PN: WO2021055880 SEQID: 12 claimed protein
  • 518: PN: WO2022056313 SEQID: 534 claimed protein
  • 1: PN: WO2022258499 SEQID: 1 claimed sequence
  • MeSH ID: D003545

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Literature & References

(2R)-2-amino-3-sulfanylpropanoic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:52-90-4
Pubchem (cid):5862
Pubchem (sid):134970857
Publications by PubMed
Inhibiting the color formation by gradient temperature-elevating Maillard reaction of soybean peptide-xylose system based on interaction of l-cysteine and Amadori compounds.
Changes in flavor precursors, pungency, and sugar content in short-day onion bulbs during 5-month storage at various temperatures or in controlled atmosphere.
Nonvolatile S-alk(en)ylthio-L-cysteine derivatives in fresh onion (Allium cepa L. cultivar).
Identification of candidate amino acids involved in the formation of pink-red pigments in onion (Allium cepa L.) juice and separation by HPLC.
Environmental stress enhances biosynthesis of flavor precursors, S-3-(hexan-1-ol)-glutathione and S-3-(hexan-1-ol)-L-cysteine, in grapevine through glutathione S-transferase activation.
Olfactory perception of 6 amino acids by human subjects.
Aromatic potential of botrytized white wine grapes: identification and quantification of new cysteine-S-conjugate flavor precursors.
Characterization of shortday onion cultivars of 3 pungency levels with flavor precursor, free amino acid, sulfur, and sugar contents.
Discovery and characterization of a novel lachrymatory factor synthase in Petiveria alliacea and its influence on alliinase-mediated formation of biologically active organosulfur compounds.
Heterologous production of methionine-gamma-lyase from Brevibacterium linens in Lactococcus lactis and formation of volatile sulfur compounds.
Silencing onion lachrymatory factor synthase causes a significant change in the sulfur secondary metabolite profile.
Nitrogen catabolite repression modulates the production of aromatic thiols characteristic of Sauvignon Blanc at the level of precursor transport.
Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase.
Modified method for rapid quantitation of S-alk(en)yl-L-cysteine sulfoxide in yellow onions (Allium cepa L.).
Volatile organic sulfur-containing constituents in Poncirus trifoliata (L.) Raf. (Rutaceae).
YtjE from Lactococcus lactis IL1403 Is a C-S lyase with alpha, gamma-elimination activity toward methionine.
Production of volatile organic sulfur compounds (VOSCs) by basidiomycetous yeasts.
Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties.
Cysteine sulfoxides and alliinase activity of some Allium species.
Volatile compounds thermally generated from S-propylcysteine and S-propylcysteine sulfoxide-aroma precursors of Allium vegetables.
Purification and Characterization of Cystathionine (gamma)-Lyase from Lactococcus lactis subsp. cremoris SK11: Possible Role in Flavor Compound Formation during Cheese Maturation.
Interspecific hybrid between Allium cepa and Allium sativum.
Hydrogen sulfide is a novel gasotransmitter with pivotal role in regulating lateral root formation in plants.
ω-Hydroxyundec-9-enoic acid induces apoptosis through ROS-mediated endoplasmic reticulum stress in non-small cell lung cancer cells.
Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway.
Development and Validation of S-Allyl-L-Cysteine in Rat Plasma Using a Mixed-Mode Reversed-Phase and Cation-Exchange LC-ESI-MS/MS Method: Application to Pharmacokinetic Studies.
Homocysteine induces cytotoxicity and proliferation inhibition in neural stem cells via DNA methylation in vitro.
Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis.
Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway.
Alternative Biomarkers of n-Hexane exposure: Characterization of aminoderived pyrroles and thiol-pyrrole conjugates in urine of rats exposed to 2,5-Hexanedione.
CuInS(2) quantum dots/poly((L)-glutamic acid)-drug conjugates for drug delivery and cell imaging.
Graphene quantum dots/L-cysteine coreactant electrochemiluminescence system and its application in sensing lead(II) ions.
Potential therapeutic effects of functionally active compounds isolated from garlic.
The role of oxidative stress in citreoviridin-induced DNA damage in human liver-derived HepG2 cells.
Sulforaphane induces reactive oxygen species-mediated mitotic arrest and subsequent apoptosis in human bladder cancer 5637 cells.
Purification and characterization of peroxidase from avocado (Persea americana Mill, cv. Hass).
Alternative chelating agents: evaluation of the ready biodegradability and complexation properties.
Oxidative stress contributes to gold nanoparticle-induced cytotoxicity in human tumor cells.
Development of a minimal chemically defined medium for Ketogulonicigenium vulgare WSH001 based on its genome-scale metabolic model.
Antioxidant changes during domestic food processing of the white shaft and green leaves of leek (Allium ampeloprasum var. porrum).
Aflatoxin G1-induced oxidative stress causes DNA damage and triggers apoptosis through MAPK signaling pathway in A549 cells.
Preparation of protein-like silver-cysteine hybrid nanowires and application in ultrasensitive immunoassay of cancer biomarker.
A 'conovenomic' analysis of the milked venom from the mollusk-hunting cone snail Conus textile--the pharmacological importance of post-translational modifications.
Dose-dependent folic acid and memantine treatments promote synergistic or additive protection against Aβ(25-35) peptide-induced apoptosis in SH-SY5Y cells mediated by mitochondria stress-associated death signals.
Activation of the epithelial-to-mesenchymal transition factor snail mediates acetaldehyde-induced intestinal epithelial barrier disruption.
Simultaneous quantitation and identification of organic and inorganic selenium in diet supplements by liquid chromatography with tandem mass spectrometry.
Olfactory transduction pathways in the Senegalese sole Solea senegalensis.
Protective effects of 6-hydroxy-1-methylindole-3-acetonitrile on cisplatin-induced oxidative nephrotoxicity via Nrf2 inactivation.
Comparative analysis of ER stress response into HIV protease inhibitors: lopinavir but not darunavir induces potent ER stress response via ROS/JNK pathway.
Structures and antioxidant and intestinal disaccharidase inhibitory activities of A-type proanthocyanidins from peanut skin.
Antiproliferative and apoptotic effects of spanish honeys.
Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food.
Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells.
Reduced scytonemin isolated from Nostoc commune induces autophagic cell death in human T-lymphoid cell line Jurkat cells.
Modulation of antioxidant defense system by the dithiocarbamate fungicides Maneb and Zineb in Chinese hamster V79 cells and the role of N-acetyl-L-cysteine.
Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.).
Mast cell-based electrochemical biosensor for quantification of the major shrimp allergen Pen a 1 (tropomyosin).
Dietary L-cysteine improves the antioxidative potential and lipid metabolism in rats fed a normal diet.
γ-Tocotrienol induced cell cycle arrest and apoptosis via activating the Bax-mediated mitochondrial and AMPK signaling pathways in 3T3-L1 adipocytes.
Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.
Formation of cysteine-S-conjugates in the Maillard reaction of cysteine and xylose.
Intestinal transport of methylmercury and inorganic mercury in various models of Caco-2 and HT29-MTX cells.
Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells.
Characterization of L-cysteine capped CdTe quantum dots and application to test Cu(II) deficiency in biological samples from critically ill patients.
Application' and validation of autochthonous lactic acid bacteria starter cultures for controlled leek fermentations and their influence on the antioxidant properties of leek.
Genotoxicity of 2-bromo-3'-chloropropiophenone.
Structures and reactions of compounds involved in pink discolouration of onion.
Oxidative DNA damage is involved in ochratoxin A-induced G2 arrest through ataxia telangiectasia-mutated (ATM) pathways in human gastric epithelium GES-1 cells in vitro.
Purification and characterisation of two enzymes related to endogenous formaldehyde in Lentinula edodes.
Purification, properties and cDNA cloning of glutamate decarboxylase in germinated faba bean (Vicia faba L.).
Combination effects of dietary soy and methylselenocysteine in a mouse model of prostate cancer.
Glutathione enhances 2-keto-l-gulonic acid production based on Ketogulonicigenium vulgare model iWZ663.
Foodomics platform for the assay of thiols in wines with fluorescence derivatization and ultra performance liquid chromatography mass spectrometry using multivariate statistical analysis.
Effect of polyphenols on oxymyoglobin oxidation: prooxidant activity of polyphenols in vitro and inhibition by amino acids.
Verrucarin A enhances TRAIL-induced apoptosis via NF-κB-mediated Fas overexpression.
Validation and clinical application of an UHPLC method for simultaneous analysis of total homocysteine and cysteine in human plasma.
Antagonistic effect of Pseudomonas graminis CPA-7 against foodborne pathogens in fresh-cut apples under simulated commercial conditions.
Purification and characterization of membrane-bound polyphenoloxidase (mPPO) from Snake fruit [Salacca zalacca (Gaertn.) Voss].
Microbial ecology of sorghum sourdoughs: effect of substrate supply and phenolic compounds on composition of fermentation microbiota.
An iTRAQ-based mitoproteomics approach for profiling the nephrotoxicity mechanisms of ochratoxin A in HEK 293 cells.
Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathway.
Speciation of inorganic- and methyl-mercury in biological matrixes by electrochemical vapor generation from an L-cysteine modified graphite electrode with atomic fluorescence spectrometry detection.
Influence of cultivar and harvest time on the amounts of isoalliin and methiin in leek (Allium ampeloprasum var. porrum).
Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1.
Selenium and zinc internalized by Lactobacillus buchneri Lb26 (DSM 16341) and Bifidobacterium lactis Bb1 (DSM 17850): improved bioavailability using a new biological approach.
The chinese herbal decoction danggui buxue tang inhibits angiogenesis in a rat model of liver fibrosis.
Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line.
A novel and highly sensitive acetyl-cholinesterase biosensor modified with hollow gold nanospheres.
Platycodin D induces reactive oxygen species-mediated apoptosis signal-regulating kinase 1 activation and endoplasmic reticulum stress response in human breast cancer cells.
A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis.
Reconstruction and analysis of a genome-scale metabolic model of the vitamin C producing industrial strain Ketogulonicigenium vulgare WSH-001.
Crosstalk between endoplasmic reticulum stress and oxidative stress in apoptosis induced by α-tocopheryl succinate in human gastric carcinoma cells.
Effect of chromium dinicocysteinate supplementation on circulating levels of insulin, TNF-α, oxidative stress, and insulin resistance in type 2 diabetic subjects: randomized, double-blind, placebo-controlled study.
Beta-eleostearic acid induce apoptosis in T24 human bladder cancer cells through reactive oxygen species (ROS)-mediated pathway.
Enzymatic synthesis oF L-tryptophan from D,L-2-amino-delta2-thiazoline-4-carboxylic acid and indole by Pseudomonas sp. TS1138 L-2-amino-delta2-thiazoline-4-carboxylic acid hydrolase, S-carbamyl-L-cysteine amidohydrolase, and Escherichia coli L-tryptophanase.
Diallyl trisulfide induces apoptosis of human basal cell carcinoma cells via endoplasmic reticulum stress and the mitochondrial pathway.
Ochratoxin A induces oxidative DNA damage and G1 phase arrest in human peripheral blood mononuclear cells in vitro.
Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells.
Inhibiting the color formation by gradient temperature-elevating Maillard reaction of soybean peptide-xylose system based on interaction of l-cysteine and Amadori compounds.
Cytotoxicity of peptide-coated silver nanoparticles on the human intestinal cell line Caco-2.
Effect of processing and storage time on the contents of organosulfur compounds in pickled blanched garlic.
Using antibrowning agents to enhance quality and safety of fresh-cut avocado treated with intense light pulses.
Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5.
Production of a conjugated fatty acid by Bifidobacterium breve LMC520 from α-linolenic acid: conjugated linolenic acid (CLnA).
Effects of thymol on B16-F10 melanoma cells.
Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides.
Oxidative stress impairs HIF1α activation: a novel mechanism for increased vulnerability of steatotic hepatocytes to hypoxic stress.
Purification and characterization of a hexanol-degrading enzyme extracted from apple.
Molecular mechanisms of apoptosis induction by 2-dodecylcyclobutanone, a radiolytic product of palmitic acid, in human lymphoma U937 cells.
Ascorbate prevents placental oxidative stress and enhances birth weight in hypoxic pregnancy in rats.
Changes in flavor precursors, pungency, and sugar content in short-day onion bulbs during 5-month storage at various temperatures or in controlled atmosphere.
Purification of diamine oxidase and its properties in germinated fava bean (Vicia faba L.).
Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
[Improvement of the method for methylmercury determination in aquatic products using liquid chromatography online coupled with atomic fluorescence spectrometry].
New insights into the metabolism of organomercury compounds: mercury-containing cysteine S-conjugates are substrates of human glutamine transaminase K and potent inactivators of cystathionine γ-lyase.
Optimized method for determining free L-cysteine in rat plasma by high-performance liquid chromatography with the 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole conversion reagent.
Clinical and nutritional benefits of cysteine-enriched protein supplements.
Echinacea alkamides prevent lipopolysaccharide/D-galactosamine-induced acute hepatic injury through JNK pathway-mediated HO-1 expression.
Role of precursors on greening in crushed garlic (Allium sativum) bulbs, and its control with freeze-dried onion powder.
Structure and bioactivity of thiosulfinates resulting from suppression of lachrymatory factor synthase in onion.
Nonvolatile S-alk(en)ylthio-L-cysteine derivatives in fresh onion (Allium cepa L. cultivar).
Exopolysaccharide of Laetiporus sulphureus var. miniatus downregulates LPS-induced production of NO, PGE₂, and TNF-α in BV2 microglia cells via suppression of the NF-κB pathway.
Allium species from Central and Southwest Asia are rich sources of marasmin.
Oral activity of FMRFamide-related peptides on the pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) and degradation by enzymes from the aphid gut.
Partial purification and characterisation of cysteine protease in wheat germ.
Identification of candidate amino acids involved in the formation of pink-red pigments in onion (Allium cepa L.) juice and separation by HPLC.
Spore germination of the psychrotolerant, red meat spoiler, Clostridium frigidicarnis.
Anticancer activity of S-allylmercapto-L-cysteine on implanted tumor of human gastric cancer cell.
Nutritional and medicinal aspects of D-amino acids.
Inhibitory effects of enterococci on the production of hydrogen sulfide by hydrogen sulfide-producing bacteria in raw meat.
Acetaldehyde and gastric cancer.
New cysteine-S-conjugate precursors of volatile sulfur compounds in bell peppers (Capsicum annuum L. cultivar).
Short-term exposure to nickel alters the adult rat brain antioxidant status and the activities of crucial membrane-bound enzymes: neuroprotection by L-cysteine.
The antioxidant activity of vitamin C, DPPD and L-cysteine against Cisplatin-induced testicular oxidative damage in rats.
Contribution of sulfur-containing compounds to the colour-inhibiting effect and improved antioxidant activity of Maillard reaction products of soybean protein hydrolysates.
Protective effect of N-acetyl-L-cysteine against maneb induced oxidative and apoptotic injury in Chinese hamster V79 cells.
Effect of genetic characteristics and environmental factors on organosulfur compounds in garlic ( Allium sativum L.) grown in Andalusia, Spain.
3-Sulfanylhexanol precursor biogenesis in grapevine cells: the stimulating effect of Botrytis cinerea.
l-Cysteine, N-Acetyl-l-cysteine, and Glutathione Protect Xenopus laevis Embryos against Acrylamide-Induced Malformations and Mortality in the Frog Embryo Teratogenesis Assay.
Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase.
Quercetin Prevents Unloading-Derived Disused Muscle Atrophy by Attenuating the Induction of Ubiquitin Ligases in Tail-Suspension Mice.
3-(allyltrisulfanyl)-2-aminopropanoic acid, a novel nonvolatile water-soluble antimicrobial sulfur compound in heated garlic.
Secreted fungal sulfhydryl oxidases: sequence analysis and characterisation of a representative flavin-dependent enzyme from Aspergillus oryzae.
Comparison on characterization of longan (Dimocarpus longan Lour.) polyphenoloxidase using endogenous and exogenous substrates.
Surface treatments and coatings to maintain fresh-cut mango quality in storage.
Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite.
The effect of the combination of reducing and oxidising agents on the viscoelastic properties of dough and sensory characteristics of buns.
Hepatoprotective effects of apple polyphenols on CCl4-induced acute liver damage in mice.
6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5.
Olfactory perception of 6 amino acids by human subjects.
Cysteine sulfoxides and volatile sulfur compounds from Allium tripedale.
Cloud point extraction combined with electrothermal atomic absorption spectrometry for the speciation of antimony(III) and antimony(V) in food packaging materials.
Characterization of shortday onion cultivars of 3 pungency levels with flavor precursor, free amino acid, sulfur, and sugar contents.
Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics.
Determination of arsenic in foods by flow injection on-line sorption pre-concentration with hydride generation atomic fluorescence spectrometry.
(-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species.
Effects of Manduca sexta allatostatin and an analog on the pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) and degradation by enzymes from the aphid gut.
L-cysteine supplementation attenuates local inflammation and restores gut homeostasis in a porcine model of colitis.
Exercise-induced elevation in plasma oxidative generating capability augments the temporal inflammatory response stimulated by lipopolysaccharide.
Synthesis and characterization of mercapturic acid (N-acetyl-L-cysteine)-aflatoxin B1 adduct and its quantitation in rat urine by an enzyme immunoassay.
[Resistance of Lactobacillus casei subsp. casei SY13 and Lactobacillus delbrueckii subsp. bulgaricus LJJ to reactive oxygen species].
Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells.
Heterologous production of methionine-gamma-lyase from Brevibacterium linens in Lactococcus lactis and formation of volatile sulfur compounds.
Optimization of a reconstituted skim milk based medium for enhanced CLA production by bifidobacteria.
The effects of green tea (-)-epigallocatechin-3-gallate on reactive oxygen species in 3T3-L1 preadipocytes and adipocytes depend on the glutathione and 67 kDa laminin receptor pathways.
Advances in protein-amino acid nutrition of poultry.
Olfactory perception of cysteine-S-conjugates from fruits and vegetables.
Biochemical and spectroscopic characterization of morning glory peroxidase from an invasive and hallucinogenic plant weed Ipomoea carnea.
Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study population.
Comparative study on essential oils incorporated into an alginate-based edible coating to assure the safety and quality of fresh-cut Fuji apples.
Induction of apoptosis by S-allylmercapto-L-cysteine, a biotransformed garlic derivative, on a human gastric cancer cell line.
Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols.
Carbon-centered radicals in isolated soy proteins.
l-Cysteine and glutathione restore the modulation of rat frontal cortex Na+, K+ -ATPase activity induced by aspartame metabolites.
Comparison of methods with respect to efficiencies, recoveries, and quantitation of mercury species interconversions in food demonstrated using tuna fish.
Impact of different green manures on the content of S-alk(en)yl-L-cysteine sulfoxides and L-ascorbic acid in leek (Allium porrum).
Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase.
Characterization of covalent addition products of chlorogenic acid quinone with amino acid derivatives in model systems and apple juice by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Identification of Genes Responding to Low-Dose Arsenite Using HiCEP.
Shelf-life of minimally processed lettuce and cabbage treated with gaseous chlorine dioxide and cysteine.
Apple peel as a contributor to whole fruit quantity of potentially healthful bioactive compounds. Cultivar and year implication.
Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice.
Anti-amyloidogenic activity of S-allyl-L-cysteine and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro.
Potential role of cysteine and methionine in the protection against hormonal imbalance and mutagenicity induced by furazolidone in female rats.
Preparation and application of L-cysteine-modified CdSe/CdS core/shell nanocrystals as a novel fluorescence probe for detection of nucleic acid.
Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
S-alk(en)yl-L-cysteine sulfoxides and relative pungency measurements of photosynthetic and nonphotosynthetic tissues of Allium porrum.
Volatile organic sulfur-containing constituents in Poncirus trifoliata (L.) Raf. (Rutaceae).
Expression of the mucus adhesion genes Mub and MapA, adhesion-like factor EF-Tu and bacteriocin gene plaA of Lactobacillus plantarum 423, monitored with real-time PCR.
Cytoprotective effects of selenium on cadmium-induced LLC-PK1 cells apoptosis by activating JNK pathway.
Areca nut extract suppresses T-cell activation and interferon-gamma production via the induction of oxidative stress.
Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms.
Improved synthesis methods of standards used for quantitative determination of total isothiocyanates from broccoli in human urine.
Nitrogen-fixing and cellulose-producing Gluconacetobacter kombuchae sp. nov., isolated from Kombucha tea.
Preparation, characterization, and antioxidative effects of oligomeric proanthocyanidin-L-cysteine complexes.
Oxidative DNA damage induced by Ochratoxin A in the HK-2 human kidney cell line: evidence of the relationship with cytotoxicity.
Increase in the permeability of tonoplast of garlic (Allium sativum) by monocarboxylic acids.
S-Allyl-L-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase.
Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds.
Dietary S-allyl-L-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in stroke-prone spontaneously hypertensive rats.
Changes in organosulfur compounds in garlic cloves during storage.
N-acetylcysteine is a highly available precursor for cysteine in the neonatal piglet receiving parenteral nutrition.
Determination of seven organosulfur compounds in garlic by high-performance liquid chromatography.
Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor.
Model studies on precursor system generating blue pigment in onion and garlic.
Cystathionine gamma-lyase contributes to selenomethionine detoxification and cytosolic glutathione peroxidase biosynthesis in mouse liver.
Characterization of germination receptors of Bacillus cereus ATCC 14579.
Reactive oxygen species mediate shear stress-induced fluid-phase endocytosis in vascular endothelial cells.
Involvement of reactive oxygen species in the immunosuppressive effect of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), a food-born carcinogenic heterocyclic amine.
Adsorption of pesticides from water by functionalized organobentonites.
Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes.
Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells.
Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.
Production of beta-galactosidase by Bifidobacteria as influenced by various culture conditions.
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
A gamma-glutamyl peptide isolated from onion (Allium cepa L.) by bioassay-guided fractionation inhibits resorption activity of osteoclasts.
Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells.
Characterization and purification of polyphenol oxidase from artichoke (Cynara scolymus L.).
Acrylonitrile-induced toxicity and oxidative stress in isolated rat colonocytes.
Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population.
Methylmercury levels in predatory fish species marketed in Canada.
Effect of simultaneous administration of vitamin C, L-cysteine and vitamin E on the melanogenesis.
Hot-water extracts from adzuki beans (Vigna angularis) suppress not only the proliferation of KATO III cells in culture but also benzo(a)pyrene-induced tumorigenesis in mouse forestomatch.
Alternative anaerobic enrichments to the bacteriological analytical manual culture method for isolation of Shigella sonnei from selected types of fresh produce.
Glutathione: a review on biotechnological production.
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC).
Renal response to lithogenic and anti-lithogenic supplement challenges in a stone-free population group.
Conjugated linoleic acid--mediated apoptosis in Jurkat T cells involves the production of reactive oxygen species.
Stereochemical course of the generation of 3-mercaptohexanal and 3-mercaptohexanol by beta-lyase-catalyzed cleavage of cysteine conjugates.
Oxidative DNA damage and glioma cell death induced by tetrahydropapaveroline.
Synthesis of isothiocyanate-derived mercapturic acids.
Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry.
Purification and characterization of polyphenol oxidase from garland chrysanthemum (Chrysanthemum coronarium L.).
Four-week intravenous repeated dose toxicity study of L-cysteine in male rats.
Growth and germination of proteolytic Clostridium botulinum in vegetable-based media.
Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis. The role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis.
Dynamic viscoelastic and tensile properties of gluten and glutenin gels of common wheats of different strength.
The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells.
Naphthalene toxicity and antioxidant nutrients.
Lactobacillus reuteri DSM 20016: purification and characterization of a cystathionine gamma-lyase and use as adjunct starter in cheesemaking.
Biosynthesis of iron-sulphur clusters is a complex and highly conserved process.
Determination of S-methyl-, S-propyl-, and S-propenyl-L-cysteine sulfoxides by gas chromatography-mass spectrometry after tert-butyldimethylsilylation.
Sulfur aroma precursor present in S-glutathione conjugate form: identification of S-3-(hexan-1-ol)-glutathione in must from Vitis vinifera L. cv. Sauvignon blanc.
Characterization of some Allium hybrids by aroma precursors, aroma profiles, and alliinase activity.
Use of a novel method to characterize the response of spores of non-proteolytic Clostridium botulinum types B, E and F to a wide range of germinants and conditions.
Fate and kinetic modeling of reactivity of alkanesulfenic acids and thiosulfinates in model systems and onion homogenates.
In vitro stability and chemical reactivity of thiosulfinates.
Antioxidant functions of selected allium thiosulfinates and S-alk(en)yl-L-cysteine sulfoxides.
In vitro effect of bioactive compounds on influenza virus specific B- and T-cell responses.
Free radical scavenging and antioxidative activity of caffeic acid amide and ester analogues: structure-activity relationship.
Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).
Application of the S-pyridylethylation reaction to the elucidation of the structures and functions of proteins.
Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress.
Assessing the aromatic potential of Cabernet Sauvignon and Merlot musts used to produce rose wine by assaying the cysteinylated precursor of 3-mercaptohexan-1-ol.
Approaches to soil remediation by complexometric extraction of metal contaminants with regeneration of reagents.
Partial purification of polyphenol oxidase from Chinese cabbage Brassica rapa L.
[Degradation of thiometon in ethyl acetate].
Changes in nitrogen compounds in must and wine during fermentation and biological aging by flor yeasts.
Optimum production, stability, partial purification and inhibitory spectrum of antimicrobial compounds produced by Pediococcus pentosaceus DI.
In vitro biogeneration of pure thiosulfinates and propanethial-S-oxide.
Covalent glutathione conjugation to cyanobacterial hepatotoxin microcystin LR by F344 rat cytosolic and microsomal glutathione S-transferases.
Aflatoxin B1 degradation by flavobacterium aurantiacum in the presence of reducing conditions and seryl and sulfhydryl group inhibitors.
Evaluation of lysine and methionine production in some Lactobacilli and yeasts from ogi.
Cysteine sulfoxides and alliinase activity of some Allium species.
Polyamines and thiols in the cytoprotective effect of L-cysteine and L-methionine on carbon tetrachloride-induced hepatotoxicity.
Comparison of different reducing agents for enhanced detection of heat-injured Listeria monocytogenes.
Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c.
Effect of amino acids on the composition and properties of extruded mixtures of wheat flour and glucose.
Picomolar quantitation of free sulfite in foods by means of [57Co]hydroxocobalamin and radiometric chromatography of [57Co]sulfitocobalamin. Method, applications and significance of coexisting sulfides.
Identification of cysteinylated aroma precursors of certain volatile thiols in passion fruit juice.
Electrophilic properties of patulin. N-acetylcysteine and glutathione adducts.
Biochemical characterization of cystine lyase from broccoli (Brassica oleracea var. italica).
Development of a simple recovery-enrichment system for enhanced detection of heat-injured Listeria monocytogenes in pasteurized milk.
A novel alliinase from onion roots. Biochemical characterization and cDNA cloning.
Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes.
Volatile compounds thermally generated from S-propylcysteine and S-propylcysteine sulfoxide-aroma precursors of Allium vegetables.
Characterization of sinapyl derivatives in pineapple (Ananas comosus [L.] Merill) juice.
Some sulfur-containing metabolites of tri-n-butyltin chloride in male rats.
Influence of L-cysteine on the formation of bitter-tasting aminohexose reductones from glucose and L-proline: identification of a novel furo[2,3-b]thiazine.
Effects of L-cysteine and N-acetyl-L-cysteine on 4-hydroxy-2, 5-dimethyl-3(2H)-furanone (furaneol), 5-(hydroxymethyl)furfural, and 5-methylfurfural formation and browning in buffer solutions containing either rhamnose or glucose and arginine.
Arecoline cytotoxicity on human oral mucosal fibroblasts related to cellular thiol and esterase activities.
Involvement of hydrogen peroxide and hydroxyl radical in chemically induced apoptosis of HL-60 cells.
Purification and characterization of cystathionine gamma-lyase from Lactobacillus fermentum DT41.
Chromium and zinc contamination of parenteral nutrient solution components commonly used in infants and children.
Lysine-overproducing mutants of Saccharomyces cerevisiae baker's yeast isolated in continuous culture.
Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.
Modification of methane emission in sheep by cysteine and a microbial preparation.
Highly ordered molten globule-like state of ovalbumin at acidic pH: native-like fragmentation by protease and selective modification of Cys367 with dithiodipyridine.
Inhibitory effect of sulfur-containing amino acids on burnt off-flavours in canned liver sausages.
Acid-induced gastric damage in rats is aggravated by starvation and prevented by several nutrients.
Dietary sulphur amino acid adequacy influences glutathione synthesis and glutathione-dependent enzymes during the inflammatory response to endotoxin and tumour necrosis factor-alpha in rats.
Antimicrobial activity of sulfur compounds derived from cabbage.
Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells.
Phenotypic variation in xenobiotic metabolism and adverse environmental response: focus on sulfur-dependent detoxification pathways.
Effects of dietary protein content, addition of nonessential amino acids and dietary methionine to cysteine balance on responses to dietary sulphur-containing amino acids in broilers.
Generalization among related complex odorant mixtures and their components: analysis of olfactory perception in the spiny lobster.
Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate.
Enhanced anticancer effect of vincristine with methionine infusion after methionine-depleting total parenteral nutrition in tumor-bearing rats.
Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver.
Association between 8-hydroxy-2'-deoxyguanosine formation and DNA strand breaks mediated by copper and iron.
Role of glutathione redox cycle in TNF-alpha-mediated endothelial cell dysfunction.
Liquid chromatographic determination of D- and L-amino acids by derivatization with o-phthaldialdehyde and N-isobutyryl-L-cysteine. Applications with reference to the analysis of peptidic antibiotics, toxins, drugs and pharmaceutically used amino acids.
Discriminative stimulus effects of excitatory amino acid agonists in rats.
Identification and quantification of the N-acetylcysteine conjugate of allyl isothiocyanate in human urine after ingestion of mustard.
Effect of selected dietary antioxidants on fatty liver-haemorrhagic syndrome in laying hens.
Tryptophanase from Escherichia coli: catalytic and spectral properties in water-organic solvents.
Quantification of D-amino acids in human urine using GC-MS and HPLC.
Separation of enantiomers of N-acetylcysteine by capillary electrophoresis after derivatization by o-phthaldialdehyde.
Requirement of thiol compounds as reducing agents for IL-2-mediated induction of LAK activity and proliferation of human NK cells.
Induction of oxidative single- and double-strand breaks in DNA by ferric citrate.
Bioavailable level and source of cysteine determine protein quality of a commercial enteral product: adequacy of tryptophan but deficiency of cysteine for rats fed an enteral product prepared fresh or stored beyond shelf life.
High-performance liquid chromatographic resolution of (R, S)-α-alkyl-α-amino acids as diastereomeric derivatives.
Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells.
Cysteine and glycine supplementation modulate the metabolic response to tumor necrosis factor alpha in rats fed a low protein diet.
Browning prevention in fresh and dehydrated potatoes by SH-containing amino acids.
Iron-mediated DNA damage: sensitive detection of DNA strand breakage catalyzed by iron.
Effects of reserpine and L-cysteine and glutathione depletion on 2-bromoethylamine hydrobromide-induced tubular necrosis in Swiss ICR mice.
Effect of selenium compounds and thiols on human mammary tumor cells.
Methylthiazolidine-4-carboxylate for treatment of acute T-2 toxin exposure.
Formation, nutritional value, and safety of D-amino acids.
Overproduction of glutathione and its derivatives by genetically engineered microbial cells.
[Histopathological evaluation of protective effect of L-cysteine in ethanol-induced liver damage in rats].
Is the toxicity of cysteine conjugates formed during mercapturic acid biosynthesis relevant to the toxicity of covalently bound drug residues?
[The subacute toxicity of glucosylthiazolidine-4-carbonic acid in rats].
[Effect of cysteine on protein metabolism in the liver of rats with ethanol-induced liver damage].
Effect of cysteine on the inactivation of cystathionine gamma-lyase by D,L-propargylglycine.
Hepatic glutathione metabolism in mice acutely treated with lead acetate.
Automated enantioseparation of amino acids by derivatization with o-phthaldialdehyde and n-acylated cysteines.
L-leucine and its analogue: specific inhibitors for S-benzyl-L-cysteine-p-nitroanilide-hydrolyzing enzyme in Escherichia coli B.
Chemotactic behavior of Campylobacter jejuni.
The C-S Lyases of Higher Plants : Direct Comparison of the Physical Properties of Homogeneous Alliin Lyase of Garlic (Allium sativum) and Onion (Allium cepa).
Salmonella decontamination of broiler carcasses with lactic acid, L-cysteine, and hydrogen peroxide.
Immunological responsiveness of mouse spleen cells after in vivo or in vitro exposure to 3-acetyldeoxynivalenol.
Improving the in vitro protein digestibility of sorghum with reducing agents.
Studies related to the mechanism of 3-BHA-induced neoplasia of the rat forestomach.
The C-S Lyases of Higher Plants : Isolation and Properties of Homogeneous Cystine Lyase from Broccoli (Brassica oleracea var botrytis) Buds.
Behavioral study of chemoreception in the sea star Marthasterias glacialis: structure-activity relationships of lactic acid, amino acids, and acetylcholine.
The utilization and safety of isomeric sulfur-containing amino acids in mice.
Primary mutagenicity screening of food additives currently used in Japan.
Captopril: pharmacology, metabolism and disposition.
The nutritional role of S-Methyl-L-cysteine.
Liver glutathione as a reservoir of L-cysteine.
Inactivation of aflatoxin B1 mutagenicity by thiols.
Inhibition of nitrosation of amines by thiols, alcohols and carbohydrates.
The oxidation of L- and D-cysteine to inorganic sulfate and taurine in the rat.
Effects of adding potassium iodate to milk before UHT treatment. I. Reduction in the amount of deposit on the heated surfaces.
A study of the rates of the competitive nitrosations of pyrrolidine, p-cresol and L-cysteine hydrochloride.
Reactivity of glycerol in intermediate moisture meats.
[Experimental evaluation of therapeutic-prophylactic nutrition in exposure to acrylonitrile].
The effect of oral doses of a polythiol resin on the excretion of methylmercury in mice treated with cysteine, D-penicillamine or phenobarbitone.
Use of L-cysteine in bread baking--results of a multi-generation feeding experiment with breeding rats.
Conditions Affecting Germination of Clostridium botulinum 62A Spores in a Chemically Defined Medium.
Biochemical studies of toxic agents. The metabolic formation of 1- and 2-menaphthylmercapturic acid.
BIOCHEMICAL STUDY OF THE TOXICITY OF S-DICHLOROVINYL-L-CYSTEINE.

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00097
HMDB (The Human Metabolome Database):HMDB00574
FooDB:FDB012678
YMDB (Yeast Metabolome Database):YMDB00046
Export Tariff Code:2930.90.5050
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
...occurs naturally in the l(+) form. available commercially as l(+)-cysteine hydrochloride.

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 121.15918731689
Melting Point 238 to 240°C @ 760 mm Hg
Vapor Pressure 2.0E-6 mmHg @ 25 °C
Flash Point TCC Value 131.5 °C TCC
logP (o/w) -2.49
Solubility
alcohol Yes
water, 1.132e+005 mg/L @ 25 °C (est) Yes
water, 2.77E+05 mg/L @ 25 °C (exp) Yes
acetone No

Occurrences

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 22 - Harmful if swallowed.
S 02 - Keep out of the reach of children.
S 20/21 - When using do not eat, drink or smoke.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1890 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Agents and Actions, A Swiss Journal of Pharmacology. Vol. 4, Pg. 125, 1974.

intravenous-rat LD50 1140 mg/kg
Journal of the American College of Toxicology. Vol. 12, Pg. 113, 1993.

intraperitoneal-rat LD50 1620 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 1251, 1973.

oral-mouse LD50 660 mg/kg
Archives of Toxicology. Vol. 41, Pg. 79, 1978.

intravenous-mouse LD50 1250 mg/kg
Yakugaku Zasshi. Journal of Pharmacy. Vol. 89, Pg. 1138, 1969.

intraperitoneal-mouse LD50 1400 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 1251, 1973.

Dermal Toxicity:
subcutaneous-rat LD50 1550 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 1251, 1973.

subcutaneous-mouse LD50 1360 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 1251, 1973.

Inhalation Toxicity:
Not determined

Safety in use information

Category:
special dietary and nutritional additives
Recommendation for laevo-cysteine usage levels up to:
not for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU): 547.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5
Click here to view publication 5
average usual ppmaverage maximum ppm
baked goods: -100.00000
beverages(nonalcoholic): -100.00000
beverages(alcoholic): --
breakfast cereal: -100.00000
cheese: --
chewing gum: --
condiments / relishes: -100.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: -100.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -100.00000
milk products: -100.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -100.00000
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008)
View page or View pdf

Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to the use of L-cysteine in foods intended for infants and young children
View page or View pdf

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

Scientific Opinion on the safety and efficacy of the use of amino acids (chemical group 34) when used as flavourings for all animal species
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list
View page or View pdf

Outcome of the consultation with Member States and EFSA on the basic substance application for L-cysteine for use in plant protection as insecticide
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):52-90-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5862
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
(2R)-2-amino-3-sulfanylpropanoic acid
Chemidplus:0000052904
RTECS:HA1600000 for cas# 52-90-4