marine nitrile

Marine nitrile, also referred to as cyclomugual nitrile (PFW) or by its systematic name 1,2,3,4,5,6,7,8-octahydro-8,8-dimethyl-2-naphthalenecarbonitrile, is a synthetic organic compound used in fragrance formulations. It presents as a colorless to pale liquid with a molecular formula of C₁₃H₁₉N and a molecular weight of approximately 189.3 g/mol. The compound offers a distinctive olfactory profile described as citrus, marine, and earthy, making it valuable as a perfuming agent. This nitrile derivative features characteristics documented in the PubChem database (CID 166374). Marine nitrile is typically synthesized for industrial use rather than sourced from natural materials, and it is incorporated into fragrances to impart fresh, aquatic, and citrus nuances.

Marine nitrile does not naturally occur in the environment but is manufactured for specific applications in the fragrance industry. Its odor qualities include citrus and marine notes with an earthy undertone, which make it suitable for enhancing leather, powder, spice, tobacco, and woody fragrance compositions. The compound's performance and safety parameters align with regulatory frameworks such as the IFRA Code of Practice (Global), which provides usage level recommendations for fragrance ingredients. Being primarily used as a perfuming agent, marine nitrile's application focuses on imparting complex sensory profiles in perfumes and related scented products.

Marine nitrile exhibits physical and chemical properties that influence its formulation and handling. It is a stable compound with an estimated log P of 3.895, indicating moderate lipophilicity. At atmospheric pressure, its boiling point ranges between 305 and 307°C, suggesting low volatility under ambient conditions. Vapor pressure at 25°C is very low (approximately 0.001 mmHg), which correlates with its low evaporation rate. The flash point is around 93°C (200°F), so precautions should be observed for flammability at elevated temperatures. Solubility data indicates it dissolves in alcohol and very slightly in water (estimated 4.681 mg/L at 25°C). The molecule’s structure presents resilience against alkalis, reflecting chemical stability, which is beneficial for storage and formulation longevity.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2926.90.0000
ChemSpider:	View

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for marine nitrile usage levels up to:
	0.8000 % in the fragrance concentrate.
Recommendation for marine nitrile flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):72928-51-9

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :166374

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

8,8-dimethyl-2,3,4,5,6,7-hexahydro-1H-naphthalene-2-carbonitrile

Chemidplus:0072928519